Effect of Vitamin D Analogue on Rosuvastatin-Induced Myopathy in Wistar Rats

Objectives. Statin-induced myopathy is one of the major causes of poor adherence and discontinuation of this medication. There are contrary results regarding association of vitamin D insufficiency with statin-induced myopathy. This study was done to determine the effect of the vitamin D3 analogue al...

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Bibliographic Details
Published in:	TheScientificWorld Vol. 2020; no. 2020; pp. 1 - 6
Main Authors:	Kalthur, Sneha G., Thomson, Sereen R., Ommurugan, Balaji, Chogtu, Bharti
Format:	Journal Article
Language:	English
Published:	Cairo, Egypt Hindawi Publishing Corporation 2020 Hindawi John Wiley & Sons, Inc Hindawi Limited
Subjects:	Alfacalcidol Animals Antilipemic agents Biomarkers Biopsy Calcifediol Calciferol Cardiovascular disease Creatine Creatine kinase Creatine Kinase - blood Disease Models, Animal Drug dosages Histology Hydrogenation Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects Kinases Lipids Muscles Muscular Diseases - blood Muscular Diseases - etiology Muscular Diseases - metabolism Muscular Diseases - pathology Musculoskeletal system Myopathy Oral administration Patient compliance Plasma Rats Rats, Wistar Regeneration Rosuvastatin Rosuvastatin Calcium - adverse effects Statins Statistical analysis Variance analysis Vitamin D Vitamin D - analogs & derivatives Vitamin D - metabolism Vitamin D Deficiency - complications Vitamin D3 Vitamin deficiency India
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