Antiviral activity of silver nanoparticles against the influenza A virus

• Published in: Journal of Virus Eradication Vol. 9; no. 2; p. 100330
• Main Authors: Naumenko, Krystyna, Zahorodnia, Svitlana, Pop, Calin V., Rizun, Nodari
• Format: Journal Article
• Language: English
• Published: Elsevier 01-06-2023
• Subjects: Antiviral activity; Influenza A virus; Original Research; Silver nanoparticles
• ISSN: 2055-6640; 2055-6659
• DOI: 10.1016/j.jve.2023.100330

Viral infections occupy an essential place in modern medicine, particularly a large group of diseases caused by the influenza viruses. They are rapidly transmitted and mutate quickly, which can lead to significant socio-economic consequences. Silver nanoparticles (AgNPs) are considered to be an effective antimicrobial agent. This study shows that they have strong antiviral properties against the influenza A virus infection. Their absence of cytotoxicity at inhibitory concentrations demonstrates that they could be an effective antiviral agent against this virus. As AgNPs inhibit the influenza A virus replication and spread, they could also be successfully used as a post-infection virostatic agent.