Distinct Circuits for Recovery of Eye Dominance and Acuity in Murine Amblyopia

Degrading vision by one eye during a developmental critical period yields enduring deficits in both eye dominance and visual acuity. A predominant model is that “reactivating” ocular dominance (OD) plasticity after the critical period is required to improve acuity in amblyopic adults. However, here...

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Bibliographic Details
Published in:	Current biology Vol. 28; no. 12; pp. 1914 - 1923.e5
Main Authors:	Stephany, Céleste-Élise, Ma, Xiaokuang, Dorton, Hilary M., Wu, Jie, Solomon, Alexander M., Frantz, Michael G., Qiu, Shenfeng, McGee, Aaron W.
Format:	Journal Article
Language:	English
Published:	England Elsevier Inc 18-06-2018
Subjects:	amblyopia Amblyopia - genetics Amblyopia - physiopathology Animals Dominance, Ocular - genetics Dominance, Ocular - physiology eye dominance Female leucine-rich repeat Male Mice Neurons - metabolism Nogo Receptor 1 - genetics Nogo Receptor 1 - metabolism plasticity visual acuity Visual Acuity - genetics Visual Acuity - physiology visual acuity eye dominance plasticity amblyopia leucine-rich repeat
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