Photodamage in deep tissue two-photon optical biopsy of human skin

Photodamage, induced by femtosecond laser radiation, was studied in thick samples of human skin tissue (healthy skin and neoplastic lesions). Photobleaching, photoionization, and thermomechanical damage effects were characterized comparatively. The laser power dependence of the damage rates allowed...

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Bibliographic Details
Published in:	Journal of biophotonics Vol. 8; no. 10; pp. 816 - 825
Main Authors:	Dalbosco, Luca, Zanini, Giulia, D'Amato, Elvira, Tessarolo, Francesco, Boi, Sebastiana, Bauer, Paolo, Haase, Albrecht, Antolini, Renzo
Format:	Journal Article
Language:	English
Published:	Weinheim WILEY-VCH Verlag 01-10-2015 WILEY‐VCH Verlag Wiley Subscription Services, Inc
Subjects:	Alterations Biomechanical Phenomena - radiation effects biomedical imaging Biopsy Biopsy - adverse effects Cavitation Damage Human Humans Lasers Lesions Molecular Imaging multiphoton processes nonlinear microscopy Optical Phenomena Photobleaching photodamage Photoionization Photons - adverse effects Skin - metabolism Skin - pathology Skin - radiation effects skin imaging Temperature Thresholds biomedical imaging skin imaging photodamage multiphoton processes nonlinear microscopy
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