Transcription-replication encounters, consequences and genomic instability

To ensure replication success, DNA polymerases must negotiate encounters with actively transcribing RNA polymerases that share the genome. This Review highlights the strategies used by prokaryotic and eukaryotic cells to minimize the consequences of collisions between replication forks and transcrip...

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Bibliographic Details
Published in:	Nature structural & molecular biology Vol. 20; no. 4; pp. 412 - 418
Main Authors:	Helmrich, Anne, Ballarino, Monica, Nudler, Evgeny, Tora, Laszlo
Format:	Journal Article
Language:	English
Published:	New York Nature Publishing Group US 01-04-2013 Nature Publishing Group
Subjects:	631/80/86 Biochemistry Biological Microscopy Chromatin Deoxyribonucleic acid DNA DNA polymerase DNA Replication Genetic transcription Genomic Instability Genomics Life Sciences Membrane Biology Molecular biology Physiological aspects Protein Structure review-article RNA polymerase RNA polymerases Structure Transcription, Genetic United States
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