Association of LIPC and advanced age-related macular degeneration

Purpose To determine whether there is an association between hepatic lipase ( LIPC ) and age-related macular degeneration (AMD) in two independent Caucasian cohorts. Methods A discovery cohort of 1626 patients with advanced AMD and 859 normal controls and a replication cohort of 2159 cases and 1150...

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Bibliographic Details
Published in:	Eye (London) Vol. 27; no. 2; pp. 265 - 271
Main Authors:	Lee, J, Zeng, J, Hughes, G, Chen, Y, Grob, S, Zhao, L, Lee, C, Krupa, M, Quach, J, Luo, J, Wei, X, Zhang, X, Zhu, J, Duan, Y, Ferreyra, H, Goldbaum, M, Haw, W, Shaw, P X, Tang, L, Zhang, K
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 01-02-2013 Nature Publishing Group
Subjects:	631/208/205 631/208/726/649 631/378/1689/1626 692/499 Aged Aged, 80 and over Alleles Cohort Studies Female Gene Frequency Genetic Predisposition to Disease Humans Laboratory Medicine Laboratory Study Lipase - genetics Macular Degeneration - genetics Male Medicine Medicine & Public Health Middle Aged Ophthalmology Pharmaceutical Sciences/Technology Polymorphism, Single Nucleotide Promoter Regions, Genetic - genetics Surgery Surgical Oncology advanced age-related macular degeneration genetics hepatic lipase
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