Sleep and diurnal rest-activity rhythm disturbances in a mouse model of Alzheimer’s disease

Abstract Study Objectives Accumulating evidence suggests a strong association between sleep, amyloid-beta (Aβ) deposition, and Alzheimer’s disease (AD). We sought to determine if (1) deficits in rest-activity rhythms and sleep are significant phenotypes in J20 AD mice, (2) metabotropic glutamate rec...

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Bibliographic Details
Published in:	Sleep (New York, N.Y.) Vol. 43; no. 11; p. 1
Main Authors:	Filon, Mikolaj J, Wallace, Eli, Wright, Samantha, Douglas, Dylan J, Steinberg, Lauren I, Verkuilen, Carissa L, Westmark, Pamela R, Maganti, Rama K, Westmark, Cara J
Format:	Journal Article
Language:	English
Published:	US Oxford University Press 01-11-2020
Subjects:	Advertising executives Alzheimer Disease - drug therapy Alzheimer's disease Animal behavior Animals Basic Science of Sleep and Circadian Rhythms Circadian Rhythm Electroencephalography Eye movements Glutamate Mice Sleep Sleep deprivation Sleep, REM Target marketing sleep CTEP Alzheimer’s disease EEG fenobam actigraphy J20 mice mGluR5
Online Access:	Get full text
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