Diversity of tryptophan halogenases in sponges of the genus Aplysina

ABSTRACT Marine sponges are a prolific source of novel enzymes with promising biotechnological potential. Especially halogenases, which are key enzymes in the biosynthesis of brominated and chlorinated secondary metabolites, possess interesting properties towards the production of pharmaceuticals th...

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Bibliographic Details
Published in:	FEMS microbiology ecology Vol. 95; no. 8; p. 1
Main Authors:	Gutleben, Johanna, Koehorst, Jasper J, McPherson, Kyle, Pomponi, Shirley, Wijffels, René H, Smidt, Hauke, Sipkema, Detmer
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 01-08-2019
Subjects:	Actinobacteria Actinobacteria - enzymology Actinobacteria - isolation & purification Animals Aplysina Bacteria Biosynthesis Biotechnology Bromination Caribbean Region Chemical defense Chloroflexi Chloroflexi - enzymology Chloroflexi - isolation & purification Community composition Composition Cyanobacteria Cyanobacteria - enzymology Cyanobacteria - isolation & purification Ecology Enzymes Hydrolases - chemistry Metabolites Microbial colonies Microbiology Observations Oxidoreductases - chemistry Phylogeny Polymerase chain reaction Porifera - enzymology Porifera - microbiology Proteins Proteobacteria - enzymology Proteobacteria - isolation & purification Secondary metabolites Species Sponges Symbiosis Tryptophan Caribbean Region Netherlands Halogenase bioactive compounds host-associated microbiome phylogenetic diversity marine sponges environmental enzymes
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