The relationship between clinical phenotype and kallikrein-kinin bioregulation in different forms of arthritis

Patients with rheumatoid arthritis (RA) have shown increased levels of neutrophils generating kallikrein-kinin peptides in blood which are potent mediators of inflammation. This study investigated the association between the bioregulation of kinin-mediated inflammation with the clinical, quality of...

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Bibliographic Details
Published in:	BMC musculoskeletal disorders Vol. 24; no. 1; p. 396
Main Authors:	Tan, Dino B A, Tedja, Chantalia, Kuster, Lukas, Raymond, Warren D, Harsanyi, Andreea, Chowalloor, Priya V, Misso, Neil L, Argawal, Shashi, Bhoola, Kanti D, Keen, Helen I
Format:	Journal Article
Language:	English
Published:	England BioMed Central Ltd 18-05-2023 BioMed Central BMC
Subjects:	Analysis Arthritis Arthritis, Rheumatoid - diagnosis Biomarkers Biomarkers - metabolism Blood Bradykinin Bradykinin receptors Development and progression Enzyme-linked immunosorbent assay Gout Gout - diagnostic imaging Health aspects Humans Hypertrophy Immunocytochemistry Inflammation Interleukin 12 Interleukin 6 Interleukin 8 Interleukin-6 - metabolism Kallikrein Kallikrein-kinin Kallikreins Kallikreins - analysis Kallikreins - metabolism Kininogens Kinins Kinins - analysis Kinins - metabolism Knee Laboratories Leukocytes Leukocytes (neutrophilic) Molecular weight Neutrophil Neutrophils Osteoarthritis Osteoarthritis - metabolism Pain Pain - metabolism Patient assessment Patients Phenotype Phenotypes Plasma Plasma levels Proteins Quality of Life Questionnaires Rheumatism Rheumatoid arthritis Rheumatology Synovial Fluid - metabolism Therapeutic targets Ultrasonic imaging Australia United States > US Biomarkers Arthritis Inflammation Neutrophil Bradykinin Kallikrein-kinin
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