Inhibition of breast cancer xenografts in a mouse model and the induction of apoptosis in multiple breast cancer cell lines by lactoferricin B peptide

Breast cancer has a diverse aetiology characterized by the heterogeneous expression of hormone receptors and signalling molecules, resulting in varied sensitivity to chemotherapy. The adverse side effects of chemotherapy coupled with the development of drug resistance have prompted the exploration o...

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Bibliographic Details
Published in:	Journal of cellular and molecular medicine Vol. 25; no. 15; pp. 7181 - 7189
Main Authors:	Rahman, Rizdwan, Fonseka, Alyssa Danielle, Sua, Shiang‐Chia, Ahmad, Munirah, Rajendran, Ramkumar, Ambu, Stephen, Davamani, Fabian, Khoo, Alan Soo‐Beng, Chitra, Ebenezer
Format:	Journal Article
Language:	English
Published:	England John Wiley & Sons, Inc 01-08-2021 John Wiley and Sons Inc
Subjects:	Animals anticancer peptide Antineoplastic Agents - pharmacology Antineoplastic Agents - therapeutic use Apoptosis Apoptosis - drug effects Breast cancer Cancer therapies Cell cycle Cell Line Chemotherapy Committees Drug dosages Drug resistance Epidermal growth factor Epithelial cells Female Growth rate Humans Kinases lactoferricin B Lactoferrin Lactoferrin - pharmacology Lactoferrin - therapeutic use Lymphoma Mammary Neoplasms, Experimental - drug therapy MCF-7 Cells Medical prognosis Medical research Mice Mice, Inbred NOD Mice, SCID milk peptide natural peptide Natural products Original Penicillin Peptides Tumor cell lines Tumors Variance analysis Xenografts breast cancer anticancer peptide milk peptide natural peptide lactoferricin B
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