A Mitochondria-Targeted Photosensitizer Showing Improved Photodynamic Therapy Effects Under Hypoxia

Organelle‐targeted photosensitizers have been reported to be effective photodynamic therapy (PDT) agents. In this work, we designed and synthesized two iridium(III) complexes that specifically stain the mitochondria and lysosomes of living cells, respectively. Both complexes exhibited long‐lived pho...

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Bibliographic Details

Published in:	Angewandte Chemie International Edition Vol. 55; no. 34; pp. 9947 - 9951
Main Authors:	Lv, Wen, Zhang, Zhang, Zhang, Kenneth Yin, Yang, Huiran, Liu, Shujuan, Xu, Aqiang, Guo, Song, Zhao, Qiang, Huang, Wei
Format:	Journal Article
Language:	English
Published:	Germany Blackwell Publishing Ltd 16-08-2016 Wiley Subscription Services, Inc
Edition:	International ed. in English
Subjects:	cell death Hypoxia iridium Mitochondria Photodynamic therapy singlet oxygen iridium hypoxia cell death singlet oxygen photodynamic therapy
Online Access:	Get full text
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