Efficacy of cascade plasmapheresis in comparison with conventional therapeutic plasma exchange for relapsed atypical hemolytic uremic syndrome: A case report

Atypical hemolytic uremic syndrome (aHUS) is a rare and life-threatening disease that is associated with high mortality and morbidity. The incidence of aHUS is about 1 or 2 cases per 1,000,000 per year. Etiology can be either familial or sporadic. The pathogenesis of aHUS involves dysregulation of t...

Full description

Saved in:

Bibliographic Details
Published in:	Asian journal of transfusion science Vol. 16; no. 2; pp. 283 - 286
Main Authors:	Vaidya, Ashwinkumar, Polavarapu, Isha, Prabhu, Ravindra, Mohan, Ganesh, Shastry, Shamee, Prethika, P
Format:	Journal Article
Language:	English
Published:	India Wolters Kluwer India Pvt. Ltd 01-07-2022 Medknow Publications and Media Pvt. Ltd Medknow Publications & Media Pvt. Ltd Wolters Kluwer - Medknow Wolters Kluwer Medknow Publications
Subjects:	Analysis atypical hemolytic uremic syndrome Blood clots Blood transfusions Brief Communication cascade plasmapheresis Case reports Evidence-based medicine Health aspects Kidneys Pathogenesis Plasma Plasma exchange (Therapeutics) thrombotic microangiopathy Vein & artery diseases Atypical hemolytic uremic syndrome cascade plasmapheresis thrombotic microangiopathy
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Abstract	Atypical hemolytic uremic syndrome (aHUS) is a rare and life-threatening disease that is associated with high mortality and morbidity. The incidence of aHUS is about 1 or 2 cases per 1,000,000 per year. Etiology can be either familial or sporadic. The pathogenesis of aHUS involves dysregulation of the alternative complement pathway, with predisposing mutations in complement genes. aHUS has a poor prognosis and a gradual or a relapsing (30%-86%) clinical course. The disease may present at any age but is mostly seen in children and young adults. Therapeutic plasma exchange (TPE) is one of the primary modalities of treatment in aHUS. This report presents the utilization of cascade plasmapheresis and its advantages over TPE in a patient with relapsed aHUS. There was a 73% decrement in antifactor H antibody levels following cascade plasmapheresis.
AbstractList	Atypical hemolytic uremic syndrome (aHUS) is a rare and life-threatening disease that is associated with high mortality and morbidity. The incidence of aHUS is about 1 or 2 cases per 1,000,000 per year. Etiology can be either familial or sporadic. The pathogenesis of aHUS involves dysregulation of the alternative complement pathway, with predisposing mutations in complement genes. aHUS has a poor prognosis and a gradual or a relapsing (30%–86%) clinical course. The disease may present at any age but is mostly seen in children and young adults. Therapeutic plasma exchange (TPE) is one of the primary modalities of treatment in aHUS. This report presents the utilization of cascade plasmapheresis and its advantages over TPE in a patient with relapsed aHUS. There was a 73% decrement in antifactor H antibody levels following cascade plasmapheresis.
Audience	Academic
Author	Polavarapu, Isha Shastry, Shamee Vaidya, Ashwinkumar Mohan, Ganesh Prabhu, Ravindra Prethika, P
AuthorAffiliation	1 Department of Nephrology, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India Department of Immunohematology and Blood Transfusion, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India
AuthorAffiliation_xml	– name: 1 Department of Nephrology, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India – name: Department of Immunohematology and Blood Transfusion, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India
Author_xml	– sequence: 1 givenname: Ashwinkumar surname: Vaidya fullname: Vaidya, Ashwinkumar organization: Department of Immunohematology and Blood Transfusion, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal, Karnataka – sequence: 2 givenname: Isha surname: Polavarapu fullname: Polavarapu, Isha organization: Department of Immunohematology and Blood Transfusion, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal, Karnataka – sequence: 3 givenname: Ravindra surname: Prabhu fullname: Prabhu, Ravindra organization: Department of Nephrology, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal, Karnataka – sequence: 4 givenname: Ganesh surname: Mohan fullname: Mohan, Ganesh organization: Department of Immunohematology and Blood Transfusion, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal, Karnataka – sequence: 5 givenname: Shamee surname: Shastry fullname: Shastry, Shamee organization: Department of Immunohematology and Blood Transfusion, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal, Karnataka – sequence: 6 givenname: P surname: Prethika fullname: Prethika, P organization: Department of Immunohematology and Blood Transfusion, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal, Karnataka
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/36687548$$D View this record in MEDLINE/PubMed
BookMark	eNp1kl9v0zAUxSM0xLrBO0_IEs8t_hvbPCBt04BJk3iBZ8t1rlt3SRzsdKUfhu-Ku3ZjlcAPsXxzzi831-esOuljD1X1luAZJ5h9sKsxz3YPQygxlLyoJkRrNWWiFifVBGvJpjXl8rQ6y3mFsZC1Eq-qU1bXSgquJtXva--Ds26LokfOZmcbQENrc2eHJSTIIaPQIxe7waaQY482YVyWc38P_Rhib1s0FqEdYD0Gd7Ai-OWWtl8A8jGhBK0dMjTIjtuhfKxFS-hiu93p1wm6suVt36TYwUd0sesCimeIaXxdvfS2zfDmsJ9XPz5ff7_6Or399uXm6uJ26gRh26l2WttaAhXcAZ_XSjMuqLaekLqRjCvS4FoD9g1xBIRknjLezIFLxyjnmp1XN3tuE-3KDCl0Nm1NtME8FGJaGJtKuy0YIohTUpXFa46VtqqgQHtGVYPBi8L6tGcN63kHjStjSrY9gh6_6cPSLOK90UoISnkBvD8AUvy5hjyaVVynMuhsqGQKK1xj-Ve1sKWr0PtYYK4L2ZkLSSXVkhJVVLN_qOzulsvYS5h8KPUjA94bXIo5J_BPjRNsdpkzD3F7lrlieff8h58MjyErgsu9YBPbEVK-a9cbSKZo7_q4-S_YUMXMYzzZH9RZ8Fs
CitedBy_id	crossref_primary_10_5937_sanamed0_48219 crossref_primary_10_1002_jca_22070
Cites_doi	10.5582/irdr.2014.01001 10.1111/trf.13427 10.1097/00002480-200007000-00003 10.2215/CJN.02210310 10.1182/hem.V13.6.6798 10.1016/j.semarthrit.2013.11.004 10.1016/j.transproceed.2018.02.012 10.1007/s00467-016-3369-6 10.1681/ASN.2006091069 10.1002/jca.21705 10.1038/ki.2013.373
ContentType	Journal Article
Copyright	Copyright: © 2022 Asian Journal of Transfusion Science. COPYRIGHT 2022 Medknow Publications and Media Pvt. Ltd. 2022. This article is published under (http://creativecommons.org/licenses/by-nc-sa/3.0/) (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. Copyright: © 2022 Asian Journal of Transfusion Science 2022
Copyright_xml	– notice: Copyright: © 2022 Asian Journal of Transfusion Science. – notice: COPYRIGHT 2022 Medknow Publications and Media Pvt. Ltd. – notice: 2022. This article is published under (http://creativecommons.org/licenses/by-nc-sa/3.0/) (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. – notice: Copyright: © 2022 Asian Journal of Transfusion Science 2022
DBID	NPM AAYXX CITATION 3V. 7X7 7XB 8FI 8FJ 8FK 8G5 ABUWG AFKRA AZQEC BENPR CCPQU DWQXO FYUFA GHDGH GNUQQ GUQSH K9. M0S M2O MBDVC PIMPY PQEST PQQKQ PQUKI PRINS Q9U 5PM DOA
DOI	10.4103/ajts.ajts_121_21
DatabaseName	PubMed CrossRef ProQuest Central (Corporate) ProQuest Health & Medical Collection ProQuest Central (purchase pre-March 2016) Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) Research Library (Alumni Edition) ProQuest Central (Alumni) ProQuest Central ProQuest Central Essentials ProQuest Central ProQuest One Community College ProQuest Central Korea Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student Research Library Prep ProQuest Health & Medical Complete (Alumni) Health & Medical Collection (Alumni Edition) ProQuest Research Library Research Library (Corporate) Publicly Available Content (ProQuest) ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China ProQuest Central Basic PubMed Central (Full Participant titles) DOAJ Directory of Open Access Journals
DatabaseTitle	PubMed CrossRef Publicly Available Content Database Research Library Prep ProQuest Central Student ProQuest Central Basic ProQuest Central Essentials ProQuest One Academic Eastern Edition ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest Hospital Collection Research Library (Alumni Edition) Health Research Premium Collection (Alumni) ProQuest Central China ProQuest Hospital Collection (Alumni) ProQuest Central ProQuest Health & Medical Complete Health Research Premium Collection ProQuest One Academic UKI Edition Health and Medicine Complete (Alumni Edition) ProQuest Central Korea ProQuest Research Library ProQuest One Academic ProQuest Central (Alumni)
DatabaseTitleList	Publicly Available Content Database PubMed
Database_xml	– sequence: 1 dbid: DOA name: Directory of Open Access Journals url: http://www.doaj.org/ sourceTypes: Open Website
DeliveryMethod	fulltext_linktorsrc
Discipline	Medicine
EISSN	1998-3565
EndPage	286
ExternalDocumentID	oai_doaj_org_article_151c878888464089a834de9f328d0ef5 A727297218 10_4103_ajts_ajts_121_21 36687548 10.4103/ajts.ajts_121_21_283_Efficacy
Genre	Case Reports
GroupedDBID	23N 2WC 3V. 53G 5GY 5VS 6PF 7X7 8FI 8FJ 8G5 AAWTL ABDBF ABPTK ABUWG ACDSR ACGFS ADBBV AFKRA AHMBA ALMA_UNASSIGNED_HOLDINGS AOIJS AZQEC BAWUL BBAFP BCNDV BENPR BPHCQ BVXVI DIK DWQXO E3Z EBS EJD EOJEC ESX F5P FYUFA GNUQQ GROUPED_DOAJ GUQSH GX1 H13 HYE IAO IHR ITC KQ8 M2O M48 M~E O-E O5R O5S OBODZ OK1 PADUT PIMPY PQEST PQQKQ PQUKI PRINS PROAC RMW RNS RPM TR2 TUS UKHRP W3E ABJNI ABXLX ADRAZ ALIPV C1A CCPQU HMCUK IL9 IPNFZ NPM OVD PGMZT RIG TEORI ~8M AAYXX CITATION 7XB 8FK K9. MBDVC Q9U 5PM
ID	FETCH-LOGICAL-c513y-9c99a67e254ce4b68934529af116d73481d069e0fd1c1e573f234dbe47c324493
IEDL.DBID	RPM
ISSN	0973-6247
IngestDate	Tue Oct 22 15:13:23 EDT 2024 Tue Sep 17 21:30:33 EDT 2024 Thu Oct 10 21:12:00 EDT 2024 Tue Nov 19 21:01:38 EST 2024 Tue Nov 12 23:10:09 EST 2024 Fri Aug 23 00:48:47 EDT 2024 Sat Sep 28 08:16:20 EDT 2024 Tue Nov 22 03:10:40 EST 2022
IsDoiOpenAccess	true
IsOpenAccess	true
IsPeerReviewed	true
IsScholarly	true
Issue	2
Keywords	Atypical hemolytic uremic syndrome cascade plasmapheresis thrombotic microangiopathy
Language	English
License	http://creativecommons.org/licenses/by-nc-sa/4.0 Copyright: © 2022 Asian Journal of Transfusion Science. This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
LinkModel	DirectLink
MergedId	FETCHMERGED-LOGICAL-c513y-9c99a67e254ce4b68934529af116d73481d069e0fd1c1e573f234dbe47c324493
OpenAccessLink	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855224/
PMID	36687548
PQID	2738080607
PQPubID	226525
PageCount	4
ParticipantIDs	doaj_primary_oai_doaj_org_article_151c878888464089a834de9f328d0ef5 pubmedcentral_primary_oai_pubmedcentral_nih_gov_9855224 proquest_journals_2738080607 gale_infotracmisc_A727297218 gale_infotracacademiconefile_A727297218 crossref_primary_10_4103_ajts_ajts_121_21 pubmed_primary_36687548 wolterskluwer_medknow_10_4103_ajts_ajts_121_21_283_Efficacy
PublicationCentury	2000
PublicationDate	20220701
PublicationDateYYYYMMDD	2022-07-01
PublicationDate_xml	– month: 7 year: 2022 text: 20220701 day: 01
PublicationDecade	2020
PublicationPlace	India
PublicationPlace_xml	– name: India – name: Ahmedabad
PublicationTitle	Asian journal of transfusion science
PublicationTitleAlternate	Asian J Transfus Sci
PublicationYear	2022
Publisher	Wolters Kluwer India Pvt. Ltd Medknow Publications and Media Pvt. Ltd Medknow Publications & Media Pvt. Ltd Wolters Kluwer - Medknow Wolters Kluwer Medknow Publications
Publisher_xml	– name: Wolters Kluwer India Pvt. Ltd – name: Medknow Publications and Media Pvt. Ltd – name: Medknow Publications & Media Pvt. Ltd – name: Wolters Kluwer - Medknow – name: Wolters Kluwer Medknow Publications
References	Padmanabhan (key-10.4103/0973-6247.356853-7) 2019 Jha (key-10.4103/0973-6247.356853-10) 2016 Heinen (key-10.4103/0973-6247.356853-8) 2007 key-10.4103/0973-6247.356853-2 Sinha (key-10.4103/0973-6247.356853-9) 2014 Vondrák (key-10.4103/0973-6247.356853-5) 2018 Kaplan (key-10.4103/0973-6247.356853-6) 2014 Rosove (key-10.4103/0973-6247.356853-3) 2014 Siami (key-10.4103/0973-6247.356853-11) 2000 Bajracharya (key-10.4103/0973-6247.356853-1) 2016 Noris (key-10.4103/0973-6247.356853-4) 2010
References_xml	– start-page: 34 year: 2014 ident: key-10.4103/0973-6247.356853-6 article-title: Current treatment of atypical hemolytic uremic syndrome publication-title: Intractable Rare Dis Res doi: 10.5582/irdr.2014.01001 contributor: fullname: Kaplan – start-page: 956 year: 2016 ident: key-10.4103/0973-6247.356853-10 article-title: Cascade plasmapheresis as preconditioning regimen for ABO-incompatible renal transplantation: A single-center experience publication-title: Transfusion doi: 10.1111/trf.13427 contributor: fullname: Jha – start-page: 383 year: 2000 ident: key-10.4103/0973-6247.356853-11 article-title: Plasmapheresis by using secondary membrane filters: Twelve years of experience publication-title: ASAIO J doi: 10.1097/00002480-200007000-00003 contributor: fullname: Siami – start-page: 1844 year: 2010 ident: key-10.4103/0973-6247.356853-4 article-title: Relative role of genetic complement abnormalities in sporadic and familial aHUS and their impact on clinical phenotype publication-title: Clin J Am Soc Nephrol doi: 10.2215/CJN.02210310 contributor: fullname: Noris – ident: key-10.4103/0973-6247.356853-2 doi: 10.1182/hem.V13.6.6798 – start-page: 797 year: 2014 ident: key-10.4103/0973-6247.356853-3 article-title: Thrombotic microangiopathies publication-title: Semin Arthritis Rheum doi: 10.1016/j.semarthrit.2013.11.004 contributor: fullname: Rosove – start-page: 967 year: 2018 ident: key-10.4103/0973-6247.356853-5 article-title: Successful 7-year eculizumab treatment of plasmapheresis-resistant recurrent atypical hemolytic-uremic syndrome due to complement factor H hybrid gene: A case report publication-title: Transplant Proc doi: 10.1016/j.transproceed.2018.02.012 contributor: fullname: Vondrák – start-page: 1615 year: 2016 ident: key-10.4103/0973-6247.356853-1 article-title: Atypical hemolytic uremic syndrome: A clinical conundrum publication-title: Pediatr Nephrol doi: 10.1007/s00467-016-3369-6 contributor: fullname: Bajracharya – start-page: 506 year: 2007 ident: key-10.4103/0973-6247.356853-8 article-title: Hemolytic uremic syndrome: A factor H mutation (E1172Stop) causes defective complement control at the surface of endothelial cells publication-title: J Am Soc Nephrol doi: 10.1681/ASN.2006091069 contributor: fullname: Heinen – start-page: 171 year: 2019 ident: key-10.4103/0973-6247.356853-7 article-title: Guidelines on the use of therapeutic apheresis in clinical practice – Evidence-based approach from the Writing Committee of the American Society for Apheresis: The eighth special issue publication-title: J Clin Apher doi: 10.1002/jca.21705 contributor: fullname: Padmanabhan – start-page: 1151 year: 2014 ident: key-10.4103/0973-6247.356853-9 article-title: Prompt plasma exchanges and immunosuppressive treatment improves the outcomes of anti-factor H autoantibody-associated hemolytic uremic syndrome in children publication-title: Kidney Int doi: 10.1038/ki.2013.373 contributor: fullname: Sinha
SSID	ssj0057685
Score	2.2757847
Snippet	Atypical hemolytic uremic syndrome (aHUS) is a rare and life-threatening disease that is associated with high mortality and morbidity. The incidence of aHUS is...
SourceID	doaj pubmedcentral proquest gale crossref pubmed wolterskluwer
SourceType	Open Website Open Access Repository Aggregation Database Index Database Publisher
StartPage	283
SubjectTerms	Analysis atypical hemolytic uremic syndrome Blood clots Blood transfusions Brief Communication cascade plasmapheresis Case reports Evidence-based medicine Health aspects Kidneys Pathogenesis Plasma Plasma exchange (Therapeutics) thrombotic microangiopathy Vein & artery diseases
SummonAdditionalLinks	– databaseName: DOAJ Directory of Open Access Journals dbid: DOA link: http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Nj9MwELVgDwgJIb7JsiAfkBCHsHHs2jGcCnS1F7gAEjcra4-1BZpWpKulP4b_ykycVAkIceHSSI0dOZ6x501m5pmxp1ZGLSHGXMsScsS3kFvlVQ5V8LWOgI4QVSOffjDvP1dvF0STsz_qi3LCEj1wmrhjtEi-Ij8NDaUqKltXUgWwUZZVKCAm9tLCDM5U2oMJRHfJi9bIXJfKpAClEoU8rr9s2xf040QpXCkmBqnj7f9zdx6Zp99TJ29crims3X7tstpHtunkFrvZg0o-Ty9zm12B5g679q4Pm99lPxdEFFH7HV9H7uuWcuL5BnHzqiZWAWiXLV823O_PJOT0eZaPM9L5qFCr78rhRyob5gh8ORXFbFoIvN7uNiR5fg6r9bcdtaePkHgZ2BFe8jmNAngKWNxjn04WH9-c5v25DLmfCbnLrbe21gbQt_SgzjRCHgrf1lEIHYgtR4RCWyhiEF7AzMhYoszOQBmP8E1ZeZ8dNOsGHjJeKAMmSOwsJTEj4jOAKAYLCICeZJmx54Nw3CbRbzh0W0iQrpPhSJAZe03S27cj4uzuD1Qn16uT-5c6ZewZyd7R8kYBo2hSlQIOl4iy3JwC18R4VGXsaNISl6Wf3h60x_XbQuuoDgohui5Mxh4kRdoPV2qNvqPCjmaiYpP3md5plucdIbitZgijVcZeTZTRrVJF5V9nzCG2dIMGHv6P6XvErpdUH9LlMx-xg-33C3jMrrbh4km3QH8BLNdCpw priority: 102 providerName: Directory of Open Access Journals
Title	Efficacy of cascade plasmapheresis in comparison with conventional therapeutic plasma exchange for relapsed atypical hemolytic uremic syndrome: A case report
URI	http://www.ajts.org/article.asp?issn=0973-6247;year=2022;volume=16;issue=2;spage=283;epage=286;aulast=Vaidya;type=0 https://www.ncbi.nlm.nih.gov/pubmed/36687548 https://www.proquest.com/docview/2738080607 https://pubmed.ncbi.nlm.nih.gov/PMC9855224 https://doaj.org/article/151c878888464089a834de9f328d0ef5
Volume	16
hasFullText	1
inHoldings	1
isFullTextHit
isPrint
link	http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lj9MwELboHhASQrzJsqx8QEIc0iax48RwKktXe1mEBEjcrNSZsIXNQ5uulv4Y_iszTlIlIC5cWqmxm2lnxv7GM_OFsZdaFEpAUfhKROAjvgVfSyt9SHObqQIwEKJu5LNPyYev6fsV0eTEQy-MK9q36828uizn1ebC1VY2pV0MdWKLj-cnOo0RNsjFjM0QGw4herf8En52dYs6Eb6KZNLlJmUYiEX2fdvO6cWEUWiicLIXOcr-vxfm0c70Z9Xk3ZuaMtrtD1fQPtqWTu-zez2e5MtO7gfsFlQP2e3zPmP-iP1aEUdEZne8LrjNWiqH5w1C5jIjQgFoNy3fVNzuH0fI6WSWj4vR-ahHq5_K4WfXMcwR83Lqh2layHm23TWkdH4BZX25o_F0_ohvAzHCG74kKYB3uYrH7Mvp6vPJmd8_ksG3cSh2vrZaZyoBDCstyLVCtEOZ26wIQ5UTUU6YB0pDUOShDSFORBEJma9BJhaRm9TiCTuo6gqeMR7IBJJc4GQhiBQRvwOIXTCAHDCIjDz2elCOaTrmDYMRCynSOB2OFOmxd6S9_TjizHYf1FffTG85BrGNTSniR8glg1RnKYoGuhBRmgdQxB57Rbo35NmoYFRN16CA4hJHlllSzprIjlKPHU1Gokfa6eXBeky_IrSGWqAQnasg8djTzpD24gqlMGyUODGZmNjk90yvoGs4LvDeFTz2dmKMpuyaKf_5jxmElWawwMP_vu9zdieifhBXv3zEDrZX1_CCzdr8-tidbhw73_wNQ1VDlQ
link.rule.ids	230,315,729,782,786,866,887,2107,27934,27935,53802,53804
linkProvider	National Library of Medicine
linkToHtml	http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1bb9MwFLbYkAAJcb8EBvgBCfGQNokdJ4anMjoVsU5IDIk3K3VOWLfloqUT9MfwXzknl6oB8bKXRqrt1Kk_29_xOecLY6-1yJSALHOVCMBFfguulla6EKc2URmgIUTZyLOv0dH3-OOUZHLCPhemCdq3i-WoOM9HxfKkia2scjvu48TGX-b7Og6RNsjxDruO89ULeiO9XYCJQTeRizoSrgpk1Honpe-JcXK6qkf0YfzAN4E_2I0a0f5_l-atvenvuMnbP0vyaddnTUj71sZ0cPeKj3SP3emYKJ-0xffZNSgesBvzztf-kP2ekrpEYte8zLhNagqk5xWS7TwhKQKolzVfFtxuXmTI6UyXb4ex863srq4ph19trjFHtswpk6aqIeXJal0RXPgJ5OX5murTySVeekmFd3xCvQDeejkesW8H0-P9mdu9zMG1oS_WrrZaJyoCNEgtyIVCnkQ-3yTzfZWSxI6fekqDl6W-9SGMRBYImS5ARhY5n9TiMdstygKeMu7JCKJUYGMhSE4R7wGkS-hBCmh-Bg572w-qqVrNDoO2DgHANGO_BQCHfaBR39Qjte3mi_Lih-kGyCArsjGdFSBZk16skxi7BjoTQZx6kIUOe0OYMbQmIDBwaNrUBuwuqWuZCXm7SSYpdtjeoCbOZTss7lFnurWkNpQ8hbxeeZHDnrQA3HRXKIUGp8SG0QCag-cZliACGxXxDnEOez8AscnbNMz__mMGCanpEfjsyr_7it2cHc8PzeGno8_P2a2AskqaKOg9tru6uIQXbKdOL182M_sPMGNYLQ
linkToPdf	http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1bb9MwFLbYkCYkxP0SGOAHJMRD2iR2nRieytZqCDZNAiTerNQ-ZoU1jZZO0B_Df-WcXKoGxAu8NFJjp0792f6OzzmfGXuuhVcCvA-VSCBEfguhllaGkDmbKw9oCFE28tGH9ORzdjghmZzNUV910L6dzQfF-WJQzM_q2MpyYYddnNjw9PhAZyOkDXJYOj_cYVdxzEayM9SbSZhYdB29qFMRqkSmjYdSxpEY5l9X1YA-TJzEJol7K1It3P_n9Ly1Pv0eO3n9-5L82tW3Oqx9a3Ga3vyP17rFbrSMlI-bIrfZFSjusL3j1ud-l_2ckMpEbtd86bnNKwqo5yWS7kVOkgRQzSs-L7jdHGjIaW-Xb4ez860sr7Yqhx9NzjFH1swpo6aswPF8tS4JNvwMFsvzNZWnHUy8dNIKr_iYWgG88XbcY5-mk48HR2F7qENoR7FYh9pqnasU0DC1IGcK-RL5fnMfx8qR1E7sIqUh8i62MYxS4RMh3QxkapH7SS3us91iWcBDxiOZQuoEVhaCZBXxGUD6hBE4QDM0CdjLrmNN2Wh3GLR5CASm7v8tEATsDfX8phypbtdfLC--mLaTDLIjm9GeAZI2GWU6z7BpoL1IMheBHwXsBeHG0NyA4MCuaVIcsLmksmXG5PUmuaQsYPu9kjimbf92hzzTzimVoSQq5PcqSgP2oAHhprlCKTQ8JVZMe_DsvU__DqKwVhNvURew1z0gm0WTjvnXf8wgMTUdAh_98-8-Y3unh1Pz_u3Ju8fsWkLJJXUw9D7bXV1cwhO2U7nLp_Xg_gW6A1qt
openUrl	ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Efficacy+of+cascade+plasmapheresis+in+comparison+with+conventional+therapeutic+plasma+exchange+for+relapsed+atypical+hemolytic+uremic+syndrome%3A+A+case+report&rft.jtitle=Asian+journal+of+transfusion+science&rft.au=Vaidya%2C+Ashwinkumar&rft.au=Polavarapu%2C+Isha&rft.au=Prabhu%2C+Ravindra&rft.au=Mohan%2C+Ganesh&rft.date=2022-07-01&rft.pub=Medknow+Publications+%26+Media+Pvt.+Ltd&rft.issn=0973-6247&rft.eissn=1998-3565&rft.volume=16&rft.issue=2&rft.spage=283&rft.epage=286&rft_id=info:doi/10.4103%2Fajts.ajts_121_21
thumbnail_l	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0973-6247&client=summon
thumbnail_m	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0973-6247&client=summon
thumbnail_s	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0973-6247&client=summon