Migraine: A Review on Its History, Global Epidemiology, Risk Factors, and Comorbidities

Migraine: A Review on Its History, Global Epidemiology, Risk Factors, and Comorbidities

Migraine affects more than one billion individuals each year across the world, and is one of the most common neurologic disorders, with a high prevalence and morbidity, especially among young adults and females. Migraine is associated with a wide range of comorbidities, which range from stress and s...

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Bibliographic Details
Published in:Frontiers in neurology Vol. 12; p. 800605
Main Authors: Amiri, Parastoo, Kazeminasab, Somayeh, Nejadghaderi, Seyed Aria, Mohammadinasab, Reza, Pourfathi, Hojjat, Araj-Khodaei, Mostafa, Sullman, Mark J M, Kolahi, Ali-Asghar, Safiri, Saeid
Format: Journal Article
Language:English
Published: Switzerland Frontiers Media S.A 23-02-2022
Subjects:
comorbidity
epidemiology
migraine
narrative review
Neurology
risk factors
epidemiology
risk factors
comorbidity
migraine
narrative review
Online Access:Get full text
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Summary:Migraine affects more than one billion individuals each year across the world, and is one of the most common neurologic disorders, with a high prevalence and morbidity, especially among young adults and females. Migraine is associated with a wide range of comorbidities, which range from stress and sleep disturbances to suicide. The complex and largely unclear mechanisms of migraine development have resulted in the proposal of various social and biological risk factors, such as hormonal imbalances, genetic and epigenetic influences, as well as cardiovascular, neurological, and autoimmune diseases. This review presents a comprehensive review of the most up-to-date literature on the epidemiology, and risk factors, as well as highlighting the gaps in our knowledge.
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Edited by: Simona Sacco, University of L'Aquila, Italy
This article was submitted to Headache and Neurogenic Pain, a section of the journal Frontiers in Neurology
Reviewed by: Paolo Martelletti, Sapienza University of Rome, Italy; Gianluca Serafini, Department of Neuroscience, San Martino Hospital (IRCCS), Italy
ISSN:1664-2295
1664-2295
DOI:10.3389/fneur.2021.800605