“Labile” heme critically regulates mitochondrial biogenesis through the transcriptional co-activator Hap4p in Saccharomyces cerevisiae

Heme (iron protoporphyrin IX) is a well-known prosthetic group for enzymes involved in metabolic pathways such as oxygen transport and electron transfer through the mitochondrial respiratory chain. However, heme has also been shown to be an important regulatory molecule (as “labile” heme) for divers...

Full description

Saved in:

Bibliographic Details
Published in:	The Journal of biological chemistry Vol. 295; no. 15; pp. 5095 - 5109
Main Authors:	Bouchez, Cyrielle L., Yoboue, Edgar D., de la Rosa Vargas, Livier E., Salin, Bénédicte, Cuvellier, Sylvain, Rigoulet, Michel, Duvezin-Caubet, Stéphane, Devin, Anne
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 10-04-2020 American Society for Biochemistry and Molecular Biology
Subjects:	Bioenergetics CCAAT-Binding Factor - genetics CCAAT-Binding Factor - metabolism gene regulation HAP complex Hap4p heme Hemin - metabolism labile heme mitochondria Mitochondria - metabolism mitochondrial biogenesis Organelle Biogenesis oxidation-reduction (redox) oxidative phosphorylation (OXPHOS) Oxygen Consumption Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - genetics Saccharomyces cerevisiae Proteins - metabolism Signal Transduction transcription factor yeast HAP complex transcription factor bioenergetics heme gene regulation mitochondria oxidation-reduction (redox) Hap4p labile heme mitochondrial biogenesis yeast oxidative phosphorylation (OXPHOS)
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!