Current advances in the fabrication of microneedles for transdermal delivery

The transdermal route is an excellent site for drug delivery due to the avoidance of gastric degradation and hepatic metabolism, in addition to easy accessibility. Although offering numerous attractive advantages, many available transdermal systems are not able to deliver drugs and other compounds a...

Full description

Saved in:

Bibliographic Details
Published in:	Journal of controlled release Vol. 185; pp. 130 - 138
Main Authors:	Indermun, Sunaina, Luttge, Regina, Choonara, Yahya E., Kumar, Pradeep, du Toit, Lisa C., Modi, Girish, Pillay, Viness
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 10-07-2014
Subjects:	Administration, Cutaneous Animals Drug Delivery Systems - instrumentation Equipment Design Humans Hypodermic Microinjections - instrumentation Microneedle Microscale fabrication techniques Needles Pharmaceutical Preparations - administration & dosage Hypodermic Microneedle Microscale fabrication techniques
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Abstract	The transdermal route is an excellent site for drug delivery due to the avoidance of gastric degradation and hepatic metabolism, in addition to easy accessibility. Although offering numerous attractive advantages, many available transdermal systems are not able to deliver drugs and other compounds as desired. The use of hypodermic needles, associated with phobia, pain and accidental needle-sticks has been used to overcome the delivery limitation of macromolecular compounds. The means to overcome the disadvantages of hypodermic needles has led to the development of microneedles for transdermal delivery. However, since the initial stages of microneedle fabrication, recent research has been conducted integrating various fabrication techniques for generating sophisticated microneedle devices for transdermal delivery including progress on their commercialization. A concerted effort has been made within this review to highlight the current advances of microneedles, and to provide an update of pharmaceutical research in the field of microneedle-assisted transdermal drug delivery systems. [Display omitted]
AbstractList	The transdermal route is an excellent site for drug delivery due to the avoidance of gastric degradation and hepatic metabolism, in addition to easy accessibility. Although offering numerous attractive advantages, many available transdermal systems are not able to deliver drugs and other compounds as desired. The use of hypodermic needles, associated with phobia, pain and accidental needle-sticks has been used to overcome the delivery limitation of macromolecular compounds. The means to overcome the disadvantages of hypodermic needles has led to the development of microneedles for transdermal delivery. However, since the initial stages of microneedle fabrication, recent research has been conducted integrating various fabrication techniques for generating sophisticated microneedle devices for transdermal delivery including progress on their commercialization. A concerted effort has been made within this review to highlight the current advances of microneedles, and to provide an update of pharmaceutical research in the field of microneedle-assisted transdermal drug delivery systems. The transdermal route is an excellent site for drug delivery due to the avoidance of gastric degradation and hepatic metabolism, in addition to easy accessibility. Although offering numerous attractive advantages, many available transdermal systems are not able to deliver drugs and other compounds as desired. The use of hypodermic needles, associated with phobia, pain and accidental needle-sticks has been used to overcome the delivery limitation of macromolecular compounds. The means to overcome the disadvantages of hypodermic needles has led to the development of microneedles for transdermal delivery. However, since the initial stages of microneedle fabrication, recent research has been conducted integrating various fabrication techniques for generating sophisticated microneedle devices for transdermal delivery including progress on their commercialization. A concerted effort has been made within this review to highlight the current advances of microneedles, and to provide an update of pharmaceutical research in the field of microneedle-assisted transdermal drug delivery systems. [Display omitted]
Author	du Toit, Lisa C. Pillay, Viness Modi, Girish Choonara, Yahya E. Kumar, Pradeep Indermun, Sunaina Luttge, Regina
Author_xml	– sequence: 1 givenname: Sunaina surname: Indermun fullname: Indermun, Sunaina organization: Wits Advanced Drug Delivery Platform Research Unit, Department of Pharmacy and Pharmacology, School of Therapeutic Sciences, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, 7 York Road, Parktown, 2193, South Africa – sequence: 2 givenname: Regina surname: Luttge fullname: Luttge, Regina organization: MESA+Institute for Nanotechnology, University of Twente, Enschede 7500AE, The Netherlands – sequence: 3 givenname: Yahya E. surname: Choonara fullname: Choonara, Yahya E. organization: Wits Advanced Drug Delivery Platform Research Unit, Department of Pharmacy and Pharmacology, School of Therapeutic Sciences, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, 7 York Road, Parktown, 2193, South Africa – sequence: 4 givenname: Pradeep orcidid: 0000-0002-8640-4350 surname: Kumar fullname: Kumar, Pradeep organization: Wits Advanced Drug Delivery Platform Research Unit, Department of Pharmacy and Pharmacology, School of Therapeutic Sciences, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, 7 York Road, Parktown, 2193, South Africa – sequence: 5 givenname: Lisa C. surname: du Toit fullname: du Toit, Lisa C. organization: Wits Advanced Drug Delivery Platform Research Unit, Department of Pharmacy and Pharmacology, School of Therapeutic Sciences, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, 7 York Road, Parktown, 2193, South Africa – sequence: 6 givenname: Girish surname: Modi fullname: Modi, Girish organization: Wits Advanced Drug Delivery Platform Research Unit, Department of Pharmacy and Pharmacology, School of Therapeutic Sciences, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, 7 York Road, Parktown, 2193, South Africa – sequence: 7 givenname: Viness surname: Pillay fullname: Pillay, Viness email: viness.pillay@wits.ac.za organization: Wits Advanced Drug Delivery Platform Research Unit, Department of Pharmacy and Pharmacology, School of Therapeutic Sciences, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, 7 York Road, Parktown, 2193, South Africa
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/24806483$$D View this record in MEDLINE/PubMed
BookMark	eNqNkMtKAzEUhoNU7EUfQZmlm6m5zmUlUrxBwY2uQyY5wZSZTE1mCn17U1rdKhw4m-8_l2-OJr73gNA1wUuCSXG3WW507wO0S4oJX-JUgp6hGalKlvO6FhM0S1yVs0LUUzSPcYMxFoyXF2hKeYULXrEZWq_GEMAPmTI75TXEzPls-ITMqiY4rQbX-6y3Wed0SAeAaRNi-5ANQfloIHSqzQy0bgdhf4nOrWojXJ36An08Pb6vXvL12_Pr6mGda0HIkGtlSqtUiZVIFxqmKMUloUWpRa0pg5LWpmaigabiVivLaKWJLZpGFBXDArMFuj3O3Yb-a4Q4yM5FDW2rPPRjlETwquCYCPIflCcvtGYJFUc0fRpjACu3wXUq7CXB8uBcbuTJuTw4lziVoCl3c1oxNh2Y39SP5ATcHwFITnYOgozaQZJtXAA9SNO7P1Z8A7soltw
CitedBy_id	crossref_primary_10_1002_adtp_201900141 crossref_primary_10_1016_j_addr_2021_04_002 crossref_primary_10_1111_jocd_12426 crossref_primary_10_1039_C8TB02928H crossref_primary_10_1016_j_cej_2021_130561 crossref_primary_10_1007_s11831_023_10020_3 crossref_primary_10_3109_10717544_2014_986309 crossref_primary_10_1186_s13104_024_06740_9 crossref_primary_10_3390_pharmaceutics15010169 crossref_primary_10_3390_mi12040435 crossref_primary_10_1007_s13346_024_01547_4 crossref_primary_10_1016_j_mser_2016_03_001 crossref_primary_10_2174_1570159X20666221012142247 crossref_primary_10_1007_s11095_019_2748_7 crossref_primary_10_1016_j_ejps_2018_06_014 crossref_primary_10_3390_mi9010040 crossref_primary_10_3390_pharmaceutics15112635 crossref_primary_10_1002_adtp_202200156 crossref_primary_10_1016_j_addma_2022_102953 crossref_primary_10_1016_j_addr_2021_01_022 crossref_primary_10_1021_acsami_9b02578 crossref_primary_10_3390_pharmaceutics14122689 crossref_primary_10_1016_j_jconrel_2022_04_043 crossref_primary_10_3390_pharmaceutics15010277 crossref_primary_10_1007_s13346_023_01510_9 crossref_primary_10_1002_adhm_202303921 crossref_primary_10_3390_mi9020085 crossref_primary_10_1002_adhm_201600750 crossref_primary_10_1007_s40005_021_00512_4 crossref_primary_10_1007_s40684_021_00383_y crossref_primary_10_1016_j_biomaterials_2020_120410 crossref_primary_10_1016_j_msec_2019_05_002 crossref_primary_10_1007_s11095_020_02844_6 crossref_primary_10_1002_adhm_201700326 crossref_primary_10_3390_su15108146 crossref_primary_10_1021_acssensors_4c00612 crossref_primary_10_3390_pharmaceutics12080693 crossref_primary_10_3390_pharmaceutics7040438 crossref_primary_10_1016_j_jddst_2023_104493 crossref_primary_10_1111_jdv_14722 crossref_primary_10_1016_j_nantod_2019_100828 crossref_primary_10_1080_17425247_2024_2351928 crossref_primary_10_1016_j_actbio_2023_02_001 crossref_primary_10_1016_j_jconrel_2016_09_002 crossref_primary_10_1016_j_jddst_2024_105627 crossref_primary_10_1002_jbm_b_35054 crossref_primary_10_1016_j_ejpb_2019_01_005 crossref_primary_10_1002_wnan_1690 crossref_primary_10_1007_s13534_024_00368_1 crossref_primary_10_3390_pharmaceutics14051066 crossref_primary_10_1002_advs_202203274 crossref_primary_10_1051_e3sconf_202450902002 crossref_primary_10_1016_j_jtice_2015_01_003 crossref_primary_10_1038_s41378_021_00298_3 crossref_primary_10_1016_j_isci_2020_102012 crossref_primary_10_1016_j_ejpb_2016_03_026 crossref_primary_10_1002_adhm_202302375 crossref_primary_10_1002_smtd_202301455 crossref_primary_10_1016_j_ebiom_2020_102743 crossref_primary_10_1016_j_biomaterials_2017_08_038 crossref_primary_10_1016_j_jddst_2023_104922 crossref_primary_10_2174_1567201816666190201143457 crossref_primary_10_1039_C8BM01219A crossref_primary_10_1021_acsomega_8b03164 crossref_primary_10_3390_jfb13020081 crossref_primary_10_3390_pharmaceutics13081132 crossref_primary_10_3762_bjnano_13_98 crossref_primary_10_1177_25151355211039073 crossref_primary_10_1007_s13346_020_00746_z crossref_primary_10_1016_j_ajps_2022_02_005 crossref_primary_10_1007_s00170_016_9698_6 crossref_primary_10_4274_imj_galenos_2022_83707 crossref_primary_10_1016_j_nantod_2022_101749 crossref_primary_10_1016_j_ijpharm_2020_120106 crossref_primary_10_3390_mi6101437 crossref_primary_10_1016_j_ijpharm_2015_06_025 crossref_primary_10_1109_JSEN_2019_2944847 crossref_primary_10_1016_j_carbpol_2016_09_080 crossref_primary_10_1146_annurev_chembioeng_060816_101514 crossref_primary_10_3390_pharmaceutics13070924 crossref_primary_10_1016_j_ejps_2016_01_007 crossref_primary_10_1021_acsbiomaterials_6b00414 crossref_primary_10_3390_pharmaceutics12060581 crossref_primary_10_1016_j_xphs_2019_07_020 crossref_primary_10_3390_ph15020190 crossref_primary_10_22159_ijap_2023v15i2_47076 crossref_primary_10_1016_j_ijbiomac_2023_126333 crossref_primary_10_1016_j_jconrel_2017_05_029 crossref_primary_10_1080_17425247_2023_2201494 crossref_primary_10_1364_BOE_7_001865 crossref_primary_10_1016_j_matlet_2019_02_014 crossref_primary_10_3390_pharmaceutics11070346 crossref_primary_10_1016_j_ijbiomac_2021_06_059 crossref_primary_10_1016_j_mtbio_2021_100193 crossref_primary_10_1021_acsami_9b09697 crossref_primary_10_1007_s13346_015_0238_y crossref_primary_10_1208_s12249_019_1560_3 crossref_primary_10_3390_ijms222312754 crossref_primary_10_1016_j_ijbiomac_2023_125374 crossref_primary_10_1016_j_jconrel_2019_05_038 crossref_primary_10_1016_j_jconrel_2022_05_054 crossref_primary_10_1007_s11095_016_1885_5 crossref_primary_10_1007_s10544_016_0086_7 crossref_primary_10_1517_14712598_2015_996544 crossref_primary_10_1007_s11095_017_2223_2 crossref_primary_10_3390_pharmaceutics12060569 crossref_primary_10_3390_polym13162815 crossref_primary_10_1016_j_fmre_2023_05_009 crossref_primary_10_1208_s12249_017_0730_4 crossref_primary_10_1088_1361_6439_ab222b crossref_primary_10_3390_pharmaceutics15092308 crossref_primary_10_3390_ph17020242 crossref_primary_10_1021_acsnano_2c08098 crossref_primary_10_3389_fbioe_2018_00054 crossref_primary_10_3390_pharmaceutics13020209 crossref_primary_10_1007_s12247_021_09586_x crossref_primary_10_1021_acsbiomaterials_8b00889 crossref_primary_10_1021_acsabm_8b00102 crossref_primary_10_1021_acs_molpharmaceut_2c00936 crossref_primary_10_1002_smll_202100692 crossref_primary_10_1088_1361_6439_ac6b7d crossref_primary_10_4236_aces_2019_92016 crossref_primary_10_1007_s13346_024_01656_0 crossref_primary_10_1002_adhm_202001922 crossref_primary_10_1007_s13346_015_0237_z crossref_primary_10_1016_j_bios_2024_116066 crossref_primary_10_1080_17425247_2020_1819787 crossref_primary_10_1080_10837450_2016_1189937 crossref_primary_10_4155_tde_2018_0054 crossref_primary_10_1002_smtd_201700277 crossref_primary_10_1016_j_sna_2015_05_020 crossref_primary_10_1021_acs_jcim_1c00444 crossref_primary_10_1208_s12249_018_1004_5 crossref_primary_10_1007_s13346_018_0544_2 crossref_primary_10_1021_acs_biomac_1c01213 crossref_primary_10_1016_j_jconrel_2017_11_048 crossref_primary_10_1016_j_vaccine_2022_07_018 crossref_primary_10_1021_acsami_7b00481 crossref_primary_10_1016_j_colsurfb_2014_10_009 crossref_primary_10_1016_j_jconrel_2019_10_004 crossref_primary_10_1080_21645515_2020_1767997 crossref_primary_10_1002_smll_201503093 crossref_primary_10_1016_j_ijpharm_2021_120301 crossref_primary_10_1038_srep38755 crossref_primary_10_1108_SR_09_2014_697 crossref_primary_10_1021_acsabm_0c00228 crossref_primary_10_1016_j_apsb_2019_03_007 crossref_primary_10_1002_adfm_201705952 crossref_primary_10_1007_s10544_020_00518_z crossref_primary_10_1016_j_jconrel_2017_02_011 crossref_primary_10_1159_000514321 crossref_primary_10_1016_j_jddst_2015_05_001 crossref_primary_10_1002_admi_202101856 crossref_primary_10_1098_rsos_171609 crossref_primary_10_1016_j_it_2017_10_002 crossref_primary_10_1111_exd_12723 crossref_primary_10_1016_j_jddst_2022_103518 crossref_primary_10_1007_s13346_020_00819_z crossref_primary_10_3724_zdxbyxb_2022_0428 crossref_primary_10_1016_j_bioadv_2022_212767 crossref_primary_10_1016_j_ijbiomac_2018_05_097 crossref_primary_10_1002_admi_202201115 crossref_primary_10_1002_adfm_202314022 crossref_primary_10_1016_j_colsurfb_2022_112818 crossref_primary_10_3390_polym14194027 crossref_primary_10_1016_j_jiec_2020_01_009 crossref_primary_10_2493_jjspe_82_1014 crossref_primary_10_1002_adhm_201900898 crossref_primary_10_3390_jcm10020181 crossref_primary_10_1016_j_jconrel_2019_11_023 crossref_primary_10_1080_10717544_2018_1507060 crossref_primary_10_1016_j_ijbiomac_2024_131650 crossref_primary_10_1007_s13346_017_0466_4 crossref_primary_10_1039_D2BM01275H crossref_primary_10_1007_s00216_016_9961_6 crossref_primary_10_1080_14737167_2018_1485100 crossref_primary_10_1016_j_jid_2021_07_177 crossref_primary_10_1016_j_ijpharm_2015_03_046 crossref_primary_10_3389_fchem_2023_1128255 crossref_primary_10_1007_s12540_022_01345_y crossref_primary_10_1016_j_trac_2020_116148 crossref_primary_10_1016_j_jddst_2022_104058 crossref_primary_10_1038_s41587_023_01774_z crossref_primary_10_1002_mabi_202300014 crossref_primary_10_1016_j_biopha_2016_08_026 crossref_primary_10_1002_bkcs_12524 crossref_primary_10_1016_j_biopha_2023_115048 crossref_primary_10_1002_btm2_10103 crossref_primary_10_1097_MOT_0000000000000488 crossref_primary_10_1039_C7LC00016B crossref_primary_10_1371_journal_pone_0172043 crossref_primary_10_1016_j_snb_2019_126708 crossref_primary_10_1080_01694243_2015_1101183 crossref_primary_10_1016_j_msec_2016_03_097 crossref_primary_10_1002_adem_201901358 crossref_primary_10_3390_pharmaceutics11050209 crossref_primary_10_2174_1567201820666230508121716 crossref_primary_10_1002_adbi_201700187 crossref_primary_10_1080_13543776_2020_1742324 crossref_primary_10_1016_j_jmapro_2020_12_035 crossref_primary_10_1155_2022_1633183 crossref_primary_10_1016_j_ijpharm_2021_120749 crossref_primary_10_1088_0960_1317_26_6_065013 crossref_primary_10_1016_j_addr_2021_114109 crossref_primary_10_1016_j_snb_2017_10_059 crossref_primary_10_3390_pharmaceutics12111101 crossref_primary_10_1007_s13346_021_01077_3 crossref_primary_10_53879_id_60_08_12392 crossref_primary_10_1016_j_ejpb_2021_01_005 crossref_primary_10_1039_C7TB01546A crossref_primary_10_2174_0929866528666210720142841 crossref_primary_10_1007_s40898_019_0006_8 crossref_primary_10_3390_nano13152225 crossref_primary_10_1051_matecconf_201819201039 crossref_primary_10_1016_j_xphs_2019_11_006 crossref_primary_10_1016_j_phrs_2019_104438 crossref_primary_10_3390_mi11110961 crossref_primary_10_1039_D0TB01822H crossref_primary_10_1016_j_eurpolymj_2024_112952 crossref_primary_10_3389_fbioe_2020_00827 crossref_primary_10_1002_jbm_a_36672 crossref_primary_10_1515_bmt_2019_0019 crossref_primary_10_1007_s13346_023_01475_9 crossref_primary_10_1088_1361_6439_aaa6a8 crossref_primary_10_3390_mi10100705 crossref_primary_10_1016_j_jconrel_2020_08_017 crossref_primary_10_1016_j_ijpharm_2023_123205 crossref_primary_10_1016_j_bioactmat_2023_04_003 crossref_primary_10_1016_j_jconrel_2015_09_017 crossref_primary_10_1016_j_ijpharm_2024_124159 crossref_primary_10_1007_s11051_023_05803_5 crossref_primary_10_1016_j_mfglet_2020_03_009 crossref_primary_10_1016_j_ijbiomac_2023_128482 crossref_primary_10_1016_j_jddst_2018_01_004 crossref_primary_10_1007_s13346_024_01531_y crossref_primary_10_1016_j_ijpharm_2020_119898 crossref_primary_10_1021_acsabm_4c00411 crossref_primary_10_1208_s12249_017_0855_5 crossref_primary_10_3390_pharmaceutics14010005 crossref_primary_10_3390_macromol4020019 crossref_primary_10_1016_j_actbio_2024_01_009 crossref_primary_10_1016_j_addr_2023_114724 crossref_primary_10_4155_tde_14_110 crossref_primary_10_1007_s12034_019_1848_7 crossref_primary_10_1111_jocd_12244 crossref_primary_10_1021_acsami_6b00606 crossref_primary_10_1016_j_ijbiomac_2017_07_178 crossref_primary_10_1016_j_actbio_2017_10_030 crossref_primary_10_1007_s13346_015_0245_z crossref_primary_10_1088_1758_5090_8_1_015006 crossref_primary_10_1002_admi_202200357 crossref_primary_10_1016_j_jconrel_2017_03_397 crossref_primary_10_3897_pharmacia_71_e112503 crossref_primary_10_4155_tde_2016_0015 crossref_primary_10_1007_s10544_018_0262_z crossref_primary_10_1039_C7SM00987A crossref_primary_10_1080_09205063_2022_2157671 crossref_primary_10_3390_scipharm87040027 crossref_primary_10_1016_j_ejpb_2018_11_013 crossref_primary_10_1021_acsabm_0c00570 crossref_primary_10_3390_polym14214475 crossref_primary_10_1016_j_actbio_2019_02_016 crossref_primary_10_1016_j_msec_2018_11_074 crossref_primary_10_1016_j_biopha_2022_113717 crossref_primary_10_1021_acs_molpharmaceut_0c00431 crossref_primary_10_1186_s13020_021_00567_3 crossref_primary_10_1016_j_jddst_2022_103611
Cites_doi	10.1016/j.jconrel.2005.02.002 10.1016/j.ejps.2013.03.019 10.1016/j.jconrel.2006.10.017 10.1016/j.jconrel.2012.12.030 10.1111/j.1749-6632.2009.04083.x 10.1016/j.jconrel.2012.05.030 10.1023/A:1013607400040 10.4103/0974-2077.58529 10.1038/nbt.1504 10.1073/pnas.2331316100 10.1007/s11095-011-0524-4 10.1586/17434440.3.1.1 10.1097/AJP.0b013e31816778f9 10.1109/JMEMS.2007.899339 10.1248/bpb.33.683 10.1007/s11095-010-0174-y 10.1210/jc.2009-0358 10.1016/j.mee.2012.07.022 10.1007/s11095-009-9967-2 10.1016/0095-8522(66)90018-3 10.1007/s10544-006-9024-4 10.1016/j.biomaterials.2007.12.048 10.1038/nmat3550 10.1016/j.jconrel.2004.04.003 10.1016/j.cherd.2008.06.002 10.1007/s00216-007-1692-2 10.1016/j.biomaterials.2011.01.014 10.1038/nrd1304 10.1016/j.jconrel.2010.07.104 10.1016/j.jconrel.2012.12.010 10.1007/s11095-010-0101-2 10.1177/0091270010378859 10.1016/j.jconrel.2009.06.029 10.1128/CVI.00387-06 10.1016/j.ijpharm.2013.04.045 10.1246/cl.130987 10.1007/s10544-008-9208-1 10.1517/17425247.4.1.19 10.1007/s10544-005-6171-y 10.1016/j.biomaterials.2012.06.065 10.2174/187221111795471445 10.1016/j.sna.2006.11.022 10.1016/j.addr.2012.04.005 10.1016/j.addr.2003.10.031 10.1007/s11095-010-0097-7 10.1016/j.jconrel.2011.12.026 10.1016/j.jconrel.2009.01.025 10.1016/j.jconrel.2006.02.017 10.1016/j.jconrel.2012.04.001 10.1016/j.vaccine.2005.09.049 10.1016/j.msec.2011.06.010 10.1088/0960-1317/16/3/001 10.1016/j.nano.2005.03.001 10.1016/j.drudis.2011.07.004 10.2741/2794 10.1016/j.jconrel.2012.08.015 10.1016/j.jconrel.2012.07.039 10.1016/j.addr.2012.09.035 10.1021/ac60231a004 10.1016/j.addr.2003.10.021 10.1016/j.addr.2005.12.003 10.1016/j.addr.2003.10.025 10.1109/TBME.2005.845240 10.1016/j.ijpharm.2008.08.032 10.1016/j.vaccine.2009.08.108 10.1002/smll.201000326 10.1016/j.ejpb.2013.10.001 10.1016/j.jconrel.2011.10.024 10.1109/JMEMS.2003.820293 10.1007/s11095-006-0028-9 10.1016/j.ijpharm.2010.01.024 10.1016/j.addr.2003.10.023 10.1016/j.mee.2010.12.067 10.1016/j.jconrel.2011.05.004 10.1016/j.jconrel.2010.10.033 10.1016/j.jconrel.2006.11.009 10.1016/j.jconrel.2013.05.026 10.1021/nn302639r 10.1016/j.jconrel.2012.01.042
ContentType	Journal Article
Copyright	2014 Elsevier B.V. Copyright © 2014 Elsevier B.V. All rights reserved.
Copyright_xml	– notice: 2014 Elsevier B.V. – notice: Copyright © 2014 Elsevier B.V. All rights reserved.
DBID	CGR CUY CVF ECM EIF NPM AAYXX CITATION 7QO 8FD FR3 P64 7X8
DOI	10.1016/j.jconrel.2014.04.052
DatabaseName	Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef Biotechnology Research Abstracts Technology Research Database Engineering Research Database Biotechnology and BioEngineering Abstracts MEDLINE - Academic
DatabaseTitle	MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef Engineering Research Database Biotechnology Research Abstracts Technology Research Database Biotechnology and BioEngineering Abstracts MEDLINE - Academic
DatabaseTitleList	MEDLINE - Academic Engineering Research Database MEDLINE
Database_xml	– sequence: 1 dbid: ECM name: MEDLINE url: https://search.ebscohost.com/login.aspx?direct=true&db=cmedm&site=ehost-live sourceTypes: Index Database
DeliveryMethod	fulltext_linktorsrc
Discipline	Pharmacy, Therapeutics, & Pharmacology
EISSN	1873-4995
EndPage	138
ExternalDocumentID	10_1016_j_jconrel_2014_04_052 24806483 S0168365914002855
Genre	Research Support, Non-U.S. Gov't Journal Article Review
GroupedDBID	--- --K --M .~1 0R~ 1B1 1RT 1~. 1~5 4.4 457 4G. 53G 5GY 5VS 7-5 71M 8P~ 9JM AABNK AABXZ AACTN AAEDT AAEDW AAIAV AAIKJ AAKOC AALRI AAOAW AAQFI AATCM AAXUO ABFNM ABFRF ABJNI ABMAC ABOCM ABXDB ABYKQ ABZDS ACDAQ ACGFO ACGFS ACIUM ACRLP ADBBV ADEZE AEBSH AEFWE AEKER AENEX AEZYN AFKWA AFRZQ AFTJW AFXIZ AGHFR AGUBO AGYEJ AIEXJ AIKHN AITUG AJBFU AJOXV ALCLG ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ AXJTR BKOJK BLXMC C45 CS3 DU5 EBS EFJIC EFLBG EJD EO8 EO9 EP2 EP3 F5P FDB FIRID FNPLU FYGXN G-Q GBLVA HMT IHE J1W KOM M34 M41 MO0 N9A O-L O9- OAUVE OGGZJ OVD OZT P-8 P-9 P2P PC. Q38 RIG RNS ROL RPZ SCC SDF SDG SDP SES SPC SPCBC SSM SSP SSZ T5K TEORI ~G- AAHBH AAXKI AKRWK CGR CUY CVF ECM EIF NPM .GJ 29K 3O- AAQXK AAYOK AAYXX ACNNM ADMUD AFJKZ AHHHB ASPBG AVWKF AZFZN CITATION D-I FEDTE FGOYB G-2 HVGLF HZ~ R2- SEW SPT WUQ 7QO 8FD FR3 P64 7X8
ID	FETCH-LOGICAL-c511t-cad7faa70a5016d3a22071267c59c23e729d935beb84fcaf328c1f6bb56830503
ISSN	0168-3659
IngestDate	Fri Oct 25 04:36:10 EDT 2024 Fri Oct 25 00:43:30 EDT 2024 Thu Sep 26 15:43:55 EDT 2024 Sat Sep 28 07:54:59 EDT 2024 Fri Feb 23 02:28:56 EST 2024
IsDoiOpenAccess	false
IsOpenAccess	true
IsPeerReviewed	true
IsScholarly	true
Keywords	Hypodermic Microneedle Microscale fabrication techniques
Language	English
License	Copyright © 2014 Elsevier B.V. All rights reserved.
LinkModel	OpenURL
MergedId	FETCHMERGED-LOGICAL-c511t-cad7faa70a5016d3a22071267c59c23e729d935beb84fcaf328c1f6bb56830503
Notes	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Feature-3 ObjectType-Review-1
ORCID	0000-0002-8640-4350
OpenAccessLink	https://ris.utwente.nl/ws/files/7001220/1-s2.0-S0168365914002855-main.pdf
PMID	24806483
PQID	1544000293
PQPubID	23462
PageCount	9
ParticipantIDs	proquest_miscellaneous_1548640151 proquest_miscellaneous_1544000293 crossref_primary_10_1016_j_jconrel_2014_04_052 pubmed_primary_24806483 elsevier_sciencedirect_doi_10_1016_j_jconrel_2014_04_052
PublicationCentury	2000
PublicationDate	2014-07-10
PublicationDateYYYYMMDD	2014-07-10
PublicationDate_xml	– month: 07 year: 2014 text: 2014-07-10 day: 10
PublicationDecade	2010
PublicationPlace	Netherlands
PublicationPlace_xml	– name: Netherlands
PublicationTitle	Journal of controlled release
PublicationTitleAlternate	J Control Release
PublicationYear	2014
Publisher	Elsevier B.V
Publisher_xml	– name: Elsevier B.V
References	Henry, McAllister, Allen, Prausnitz (bb0255) 1998 Smart, Subramanian (bb0260) 2008 Alarcon, Hartley, Harvey, Mikszta (bb0430) 2007; 14 Gardeniers, Luttge, Berenschot, de Boer, Yeshurun, Hefetz, van't Oever, van den Berg (bb0265) 2003; 12 Vrdoljak, McGrath, Carey, Draper, Hill, O'Mahony, Crean, Moore (bb0145) 2012; 159 Bystrova, Luttge (bb0305) 2011; 88 Hedge, Kaveri, Bayry (bb0065) 2011; 16 van der Maaden, Jiskoot, Bouwstra (bb0200) 2012; 161 Raphael, Prow, Crichton, Chen, Fernando, Kendall (bb0360) 2010; 6 Baek, Han, Min, Prausnitz, Park, Park (bb0175) 2011; 154 Lee, Park, Prausnitz (bb0385) 2008; 29 Prausnitz (bb0085) 2004; 56 Donnelly, Singh, Tunney, Morrow, McCarron, O'Mahony, Woolfson (bb0170) 2009; 26 Kim, Kim, Yang, Lee, Jung (bb0390) 2013; 170 Perennes, Marmiroli, Matteucci, Tormen, Vaccari, DiFabrizio (bb0330) 2006; 16 Lee, Lee, Jung (bb0350) 2011; 32 Ding, Verbaan, Bivas-Benita, Bungener, Huckriede, van den Berg, Kersten, Bouwstra (bb0150) 2009; 136 Doukas (bb0230) 2004; 56 Davis, Martanto, Allen, Prausnitz (bb0275) 2005; 52 Bal, Kruithof, Zwier, Dietz, Bouwstra, Lademann, Meinke (bb0290) 2010; 147 Sivamani, Liepmann, Maibach (bb0190) 2007; 4 Choi, Rajaraman, Yoon, Wu, Allen (bb0345) 2006 Kim, Quan, Yoo, Compans, Kang, Prausnitz (bb0105) 2009; 27 McAllister, Wang, Davis, Park, Canatella, Allen, Prausnitz (bb0165) 2003; 100 Bronaugh, Maibach (bb0225) 1999 Kirkland (bb0405) 1965; 37 Park, Allen, Prausnitz (bb0280) 2006; 23 Chiarello (bb0035) 2005 Doddaballapur (bb0295) 2009; 2 Birchall, Clemo, Anstey, John (bb0160) 2011; 28 Liu, Jin, Quan, Kamiyama, Kusamori, Katsumi, Sakane, Yamamoto (bb0395) 2012; 161 DeMuth, Moon, Suh, Hammond, Irvine (bb0415) 2012; 6 Prausnitz, Mitragotri, Langer (bb0010) 2004; 3 Williams, Barry (bb0025) 2004; 56 Langer (bb0005) 2004; 56 Xie, Xu, Gao (bb0015) 2005; 1 Widera, Johnson, Kim, Libiran, Nyam, Daddona, Cormier (bb0215) 2006; 24 DeMuth, Min, Huang, Kramer, Miller, Barouch, Hammond, Irvine (bb0420) 2013; 12 Teo, Shearwood, Ng, Lu, Moochhala (bb0270) 2005; 7 Martin, Allender, Brain, Morrissey, Birchall (bb0380) 2012; 158 Brogden, Milewski, Ghosh, Hardi, Crofford, Stinchcomb (bb0020) 2012; 163 Donnelly, Singh, Alkilani, McCrudden, O'Neill, O'Mahony, Armstrong, McLoone, Kole, Woolfson (bb0180) 2013; 451 Gratieri, Alberti, Lapteva, Kalia (bb0045) 2013; 50 Matsuo, Hirobe, Yokota, Ayabe, Seto, Quan, Kamiyama, Tougan, Horii, Mukai, Okada, Nakagawa (bb0140) 2012; 160 Jung, Lee, Oh, Hwang, Jung, Lee, Ko (bb0335) 2008; 20 Ochoa, Mousoulis, Ziaie (bb0310) 2012; 64 Gill, Denson, Burris, Prausnitz (bb0095) 2008; 24 Martanto, Moore, Couse, Prausnitz (bb0115) 2006; 112 Park, Allen, Prausnitz (bb0235) 2005; 104 Prausnitz, Mikszta, Cormier, Andrianov (bb0125) 2009; 333 Raphael, Meliga, Chen, Fernando, Flaim, Kendall (bb0135) 2013; 166 Prausnitz, Langer (bb0080) 2008; 26 Li, Huo, Zhou, Zhou, Hao, Liu, Zhang (bb0300) 2010; 389 Liu, Jin, Quan, Kamiyama, Kusamori, Katsumi, Sakane, Yamamoto (bb0185) 2014; 86 Escobar-Chávez, Bonilla-Martínez, Villegas-González, Molina-Trinidad, Casas-Alancaster, Revilla-Vázquez (bb0060) 2011; 51 Ariga, Yamauchi, Rydzek, Ji, Yonamine, Wu, Hill (bb0410) 2014; 43 Gill, Prausnitz (bb0120) 2007; 117 Birchall (bb0070) 2006; 3 Davidson, Al-Qallaf, Das (bb0130) 2008; 86 Ito, Hasegawa, Fukushima, Sugioka, Takada (bb0365) 2010; 33 Zhang, Brown, Siebenaler, Determan, Dohmeier, Hansen (bb0425) 2012; 29 Matriano, Cormier, Johnson, Young, Buttery, Nyam, Daddona (bb0110) 2002; 19 Luttge, Berenschot, de Boer, Altpeter, Vrouwe, van den Berg, Elwenspoek (bb0285) 2007; 16 Park, Choi, Kamath, Yoon, Allen, Prausnitz (bb0320) 2007; 9 Becker, Gärtner (bb0315) 2008; 390 Wendorf, Ghartey-Tagoe, Williams, Enioutina, Singh, Cleary (bb0370) 2011; 28 Verbaan, Bal, van den Berg, Groenink, Verpoorten, Lüttge, Bouwstra (bb0240) 2007; 117 Chu, Prausnitz (bb0210) 2011; 149 Cosman, Lane, Bolognese, Zanchetta, Garcia-Hernandez, Sees, Matriano, Gaumer, Daddona (bb0440) 2010; 95 Kim, Park, Prausnitz (bb0195) 2012; 64 Arora, Prausnitz, Mitragotri (bb0030) 2008; 364 Vandervoort, Ludwig (bb0245) 2008; 13 Ameri, Maa, Daddona (bb0435) 2006 Aoyagi, Izumi, Isono, Fukuda, Ogawa (bb0325) 2007; 139 Chong, Gonzalez-Gonzalez, Lara, Speaker, Contag, Kaspar, Coulman, Hargest, Birchall (bb0040) 2013; 166 Chen, Prow, Crichton, Jenkins, Roberts, Frazer, Fernando, Kendall (bb0155) 2009; 139 Lee, Jung (bb0205) 2012; 33 Sachdeva, Banga (bb0090) 2011; 5 You, Chang, Ju, Pak (bb0375) 2011; 31 M.S. Gerstel, V.A. Place, Drug delivery device. U.S. Pat. 3964, 1976. Haq, Smith, John, Kalavala, Edwards, Anstey, Morrissey, Birchall (bb0100) 2009; 11 Iler (bb0400) 1966; 21 Cormier, Johnson, Ameri, Nyam, Libiran, Zhang, Daddona (bb0220) 2004; 97 Fukushima, Ise, Morita, Hasegawa, Ito, Sugioka, Takada (bb0355) 2011; 28 Giudice, Campbell (bb0075) 2006; 58 Pattani, McKay, Garland, Curran, Migalska, Cassidy, Malcolm, Shattock, McCarthy, Donnelly (bb0055) 2012; 162 Al-Qallaf, Das (bb0050) 2009; 1161 Verhoeven, Bystrova, Winnubst, Qureshi, de Gruijl, Scheper, Luttge (bb0340) 2012; 98 Zhang (10.1016/j.jconrel.2014.04.052_bb0425) 2012; 29 Vandervoort (10.1016/j.jconrel.2014.04.052_bb0245) 2008; 13 You (10.1016/j.jconrel.2014.04.052_bb0375) 2011; 31 Sivamani (10.1016/j.jconrel.2014.04.052_bb0190) 2007; 4 Gill (10.1016/j.jconrel.2014.04.052_bb0120) 2007; 117 Birchall (10.1016/j.jconrel.2014.04.052_bb0160) 2011; 28 Ochoa (10.1016/j.jconrel.2014.04.052_bb0310) 2012; 64 Sachdeva (10.1016/j.jconrel.2014.04.052_bb0090) 2011; 5 Gardeniers (10.1016/j.jconrel.2014.04.052_bb0265) 2003; 12 Prausnitz (10.1016/j.jconrel.2014.04.052_bb0125) 2009; 333 Lee (10.1016/j.jconrel.2014.04.052_bb0205) 2012; 33 Park (10.1016/j.jconrel.2014.04.052_bb0280) 2006; 23 Doukas (10.1016/j.jconrel.2014.04.052_bb0230) 2004; 56 Kim (10.1016/j.jconrel.2014.04.052_bb0105) 2009; 27 Alarcon (10.1016/j.jconrel.2014.04.052_bb0430) 2007; 14 Donnelly (10.1016/j.jconrel.2014.04.052_bb0170) 2009; 26 Lee (10.1016/j.jconrel.2014.04.052_bb0385) 2008; 29 Martanto (10.1016/j.jconrel.2014.04.052_bb0115) 2006; 112 McAllister (10.1016/j.jconrel.2014.04.052_bb0165) 2003; 100 Li (10.1016/j.jconrel.2014.04.052_bb0300) 2010; 389 Martin (10.1016/j.jconrel.2014.04.052_bb0380) 2012; 158 Kim (10.1016/j.jconrel.2014.04.052_bb0390) 2013; 170 Escobar-Chávez (10.1016/j.jconrel.2014.04.052_bb0060) 2011; 51 Teo (10.1016/j.jconrel.2014.04.052_bb0270) 2005; 7 Langer (10.1016/j.jconrel.2014.04.052_bb0005) 2004; 56 Pattani (10.1016/j.jconrel.2014.04.052_bb0055) 2012; 162 10.1016/j.jconrel.2014.04.052_bb0250 Smart (10.1016/j.jconrel.2014.04.052_bb0260) 2008 Aoyagi (10.1016/j.jconrel.2014.04.052_bb0325) 2007; 139 Jung (10.1016/j.jconrel.2014.04.052_bb0335) 2008; 20 Baek (10.1016/j.jconrel.2014.04.052_bb0175) 2011; 154 Ding (10.1016/j.jconrel.2014.04.052_bb0150) 2009; 136 Hedge (10.1016/j.jconrel.2014.04.052_bb0065) 2011; 16 Ariga (10.1016/j.jconrel.2014.04.052_bb0410) 2014; 43 Liu (10.1016/j.jconrel.2014.04.052_bb0185) 2014; 86 Arora (10.1016/j.jconrel.2014.04.052_bb0030) 2008; 364 Prausnitz (10.1016/j.jconrel.2014.04.052_bb0080) 2008; 26 Iler (10.1016/j.jconrel.2014.04.052_bb0400) 1966; 21 Lee (10.1016/j.jconrel.2014.04.052_bb0350) 2011; 32 Park (10.1016/j.jconrel.2014.04.052_bb0320) 2007; 9 Liu (10.1016/j.jconrel.2014.04.052_bb0395) 2012; 161 Ito (10.1016/j.jconrel.2014.04.052_bb0365) 2010; 33 Brogden (10.1016/j.jconrel.2014.04.052_bb0020) 2012; 163 Giudice (10.1016/j.jconrel.2014.04.052_bb0075) 2006; 58 Luttge (10.1016/j.jconrel.2014.04.052_bb0285) 2007; 16 Raphael (10.1016/j.jconrel.2014.04.052_bb0360) 2010; 6 Birchall (10.1016/j.jconrel.2014.04.052_bb0070) 2006; 3 Chen (10.1016/j.jconrel.2014.04.052_bb0155) 2009; 139 Cosman (10.1016/j.jconrel.2014.04.052_bb0440) 2010; 95 Raphael (10.1016/j.jconrel.2014.04.052_bb0135) 2013; 166 Matsuo (10.1016/j.jconrel.2014.04.052_bb0140) 2012; 160 Widera (10.1016/j.jconrel.2014.04.052_bb0215) 2006; 24 Doddaballapur (10.1016/j.jconrel.2014.04.052_bb0295) 2009; 2 Kim (10.1016/j.jconrel.2014.04.052_bb0195) 2012; 64 Choi (10.1016/j.jconrel.2014.04.052_bb0345) 2006 Bal (10.1016/j.jconrel.2014.04.052_bb0290) 2010; 147 Ameri (10.1016/j.jconrel.2014.04.052_bb0435) 2006 Vrdoljak (10.1016/j.jconrel.2014.04.052_bb0145) 2012; 159 Park (10.1016/j.jconrel.2014.04.052_bb0235) 2005; 104 DeMuth (10.1016/j.jconrel.2014.04.052_bb0420) 2013; 12 Prausnitz (10.1016/j.jconrel.2014.04.052_bb0010) 2004; 3 Williams (10.1016/j.jconrel.2014.04.052_bb0025) 2004; 56 Chiarello (10.1016/j.jconrel.2014.04.052_bb0035) 2005 DeMuth (10.1016/j.jconrel.2014.04.052_bb0415) 2012; 6 Fukushima (10.1016/j.jconrel.2014.04.052_bb0355) 2011; 28 Bronaugh (10.1016/j.jconrel.2014.04.052_bb0225) 1999 Davis (10.1016/j.jconrel.2014.04.052_bb0275) 2005; 52 Kirkland (10.1016/j.jconrel.2014.04.052_bb0405) 1965; 37 Becker (10.1016/j.jconrel.2014.04.052_bb0315) 2008; 390 Chong (10.1016/j.jconrel.2014.04.052_bb0040) 2013; 166 Cormier (10.1016/j.jconrel.2014.04.052_bb0220) 2004; 97 Perennes (10.1016/j.jconrel.2014.04.052_bb0330) 2006; 16 Verhoeven (10.1016/j.jconrel.2014.04.052_bb0340) 2012; 98 Wendorf (10.1016/j.jconrel.2014.04.052_bb0370) 2011; 28 Verbaan (10.1016/j.jconrel.2014.04.052_bb0240) 2007; 117 Matriano (10.1016/j.jconrel.2014.04.052_bb0110) 2002; 19 Donnelly (10.1016/j.jconrel.2014.04.052_bb0180) 2013; 451 Henry (10.1016/j.jconrel.2014.04.052_bb0255) 1998 Prausnitz (10.1016/j.jconrel.2014.04.052_bb0085) 2004; 56 Gratieri (10.1016/j.jconrel.2014.04.052_bb0045) 2013; 50 Haq (10.1016/j.jconrel.2014.04.052_bb0100) 2009; 11 Chu (10.1016/j.jconrel.2014.04.052_bb0210) 2011; 149 van der Maaden (10.1016/j.jconrel.2014.04.052_bb0200) 2012; 161 Gill (10.1016/j.jconrel.2014.04.052_bb0095) 2008; 24 Al-Qallaf (10.1016/j.jconrel.2014.04.052_bb0050) 2009; 1161 Xie (10.1016/j.jconrel.2014.04.052_bb0015) 2005; 1 Bystrova (10.1016/j.jconrel.2014.04.052_bb0305) 2011; 88 Davidson (10.1016/j.jconrel.2014.04.052_bb0130) 2008; 86
References_xml	– volume: 16 start-page: 872 year: 2007 end-page: 884 ident: bb0285 article-title: Integrated lithographic molding for microneedle-based devices publication-title: J. Microelectromech. Syst. contributor: fullname: Elwenspoek – volume: 26 start-page: 2513 year: 2009 end-page: 2522 ident: bb0170 article-title: Microneedle arrays allow lower microbial penetration than hypodermic needles publication-title: Pharm. Res. contributor: fullname: Woolfson – volume: 20 start-page: 45 year: 2008 end-page: 53 ident: bb0335 article-title: Nickel microneedles fabricated by sequential copper and nickel electroless plating and copper chemical wet etching publication-title: Sens. Mater. contributor: fullname: Ko – volume: 4 start-page: 19 year: 2007 end-page: 25 ident: bb0190 article-title: Microneedles and transdermal applications publication-title: Expert Opin. Drug Deliv. contributor: fullname: Maibach – volume: 31 start-page: 1632 year: 2011 end-page: 1636 ident: bb0375 article-title: Rapidly dissolving fibroin microneedles for transdermal drug delivery publication-title: Mater. Sci. Eng. C contributor: fullname: Pak – volume: 86 start-page: 1196 year: 2008 end-page: 1206 ident: bb0130 article-title: Transdermal drug delivery by coated microneedles: geometry effects on effective skin thickness and drug permeability publication-title: Chem. Eng. Res. Des. contributor: fullname: Das – volume: 56 start-page: 603 year: 2004 end-page: 618 ident: bb0025 article-title: Penetration enhancers publication-title: Adv. Drug Deliv. Rev. contributor: fullname: Barry – volume: 11 start-page: 35 year: 2009 end-page: 47 ident: bb0100 article-title: Clinical administration of microneedles: skin puncture, pain and sensation publication-title: Biomed. Microdevices contributor: fullname: Birchall – volume: 97 start-page: 503 year: 2004 end-page: 511 ident: bb0220 article-title: Transdermal delivery of desmopressin using a coated microneedle array system publication-title: J. Control. Release contributor: fullname: Daddona – volume: 33 start-page: 683 year: 2010 end-page: 690 ident: bb0365 article-title: Self-dissolving micropile array chip as percutaneous delivery system of protein drug publication-title: Biol. Pharm. Bull. contributor: fullname: Takada – volume: 51 start-page: 964 year: 2011 end-page: 977 ident: bb0060 article-title: Microneedles: a valuable physical enhancer to increase transdermal drug delivery publication-title: J. Clin. Pharmacol. contributor: fullname: Revilla-Vázquez – volume: 16 start-page: 1061 year: 2011 end-page: 1068 ident: bb0065 article-title: Recent advances in the administration of vaccines for infectious diseases: microneedles as painless delivery devices for mass vaccination publication-title: Drug Discov. Today contributor: fullname: Bayry – volume: 52 start-page: 909 year: 2005 end-page: 915 ident: bb0275 article-title: Hollow metal microneedles for insulin delivery to diabetic rats publication-title: IEEE Trans. Biomed. Eng. contributor: fullname: Prausnitz – volume: 29 start-page: 2113 year: 2008 end-page: 2124 ident: bb0385 article-title: Dissolving microneedles for transdermal drug delivery publication-title: Biomaterials contributor: fullname: Prausnitz – volume: 12 start-page: 367 year: 2013 end-page: 376 ident: bb0420 article-title: Polymer multilayer tattooing for enhanced DNA vaccination publication-title: Nat. Mater. contributor: fullname: Irvine – volume: 159 start-page: 34 year: 2012 end-page: 42 ident: bb0145 article-title: Coated microneedle arrays for transcutaneous delivery of live virus vaccines publication-title: J. Control. Release contributor: fullname: Moore – volume: 64 start-page: 1603 year: 2012 end-page: 1616 ident: bb0310 article-title: Polymeric microdevices for transdermal and subcutaneous drug delivery publication-title: Adv. Drug Deliv. Rev. contributor: fullname: Ziaie – volume: 136 start-page: 71 year: 2009 end-page: 78 ident: bb0150 article-title: Microneedle arrays for the transcutaneous immunization of diphtheria and influenza in BALB/c mice publication-title: J. Control. Release contributor: fullname: Bouwstra – start-page: 46 year: 2005 end-page: 56 ident: bb0035 article-title: Breaking the barrier: advances in transdermal technology publication-title: Pharm. Technol. contributor: fullname: Chiarello – volume: 95 start-page: 151 year: 2010 end-page: 158 ident: bb0440 article-title: Effect of transdermal teriparatide administration on bone mineral density in postmenopausal women publication-title: J. Clin. Endocrinol. Metab. contributor: fullname: Daddona – volume: 13 start-page: 1711 year: 2008 end-page: 1715 ident: bb0245 article-title: Microneedles for transdermal drug delivery: a mini review publication-title: Front. Biosci. contributor: fullname: Ludwig – volume: 88 start-page: 1681 year: 2011 end-page: 1684 ident: bb0305 article-title: Micromoulding for ceramic microneedle arrays publication-title: Microelectron. Eng. contributor: fullname: Luttge – volume: 23 start-page: 1008 year: 2006 end-page: 1019 ident: bb0280 article-title: Polymer microneedles for controlled-release drug delivery publication-title: Pharm. Res. contributor: fullname: Prausnitz – volume: 166 start-page: 211 year: 2013 end-page: 219 ident: bb0040 article-title: Gene silencing following siRNA delivery to skin via coated steel microneedles: publication-title: J. Control. Release contributor: fullname: Birchall – volume: 5 start-page: 95 year: 2011 end-page: 132 ident: bb0090 article-title: Microneedles and their applications publication-title: Recent Pat. Drug Deliv. Formul. contributor: fullname: Banga – volume: 19 start-page: 63 year: 2002 end-page: 70 ident: bb0110 article-title: Macroflux microprojection array patch technology: a new and efficient approach for intracutaneous immunization publication-title: Pharm. Res. contributor: fullname: Daddona – volume: 100 start-page: 13755 year: 2003 end-page: 13760 ident: bb0165 article-title: Microfabricated needles for transdermal delivery of macromolecules and nanoparticles: fabrication methods and transport studies publication-title: PNAS contributor: fullname: Prausnitz – volume: 86 start-page: 267 year: 2014 end-page: 276 ident: bb0185 article-title: Transdermal delivery of relatively high molecular weight drugs using novel self-dissolving microneedle arrays fabricated from hyaluronic acid and their characteristics and safety after application to the skin publication-title: Eur. J. Pharm. Biopharm. contributor: fullname: Yamamoto – volume: 7 start-page: 47 year: 2005 end-page: 52 ident: bb0270 article-title: and publication-title: Biomed. Microdevices contributor: fullname: Moochhala – volume: 9 start-page: 223 year: 2007 end-page: 234 ident: bb0320 article-title: Polymer particle-based micromoulding to fabricate novel microstructures publication-title: Biomed. Microdevices contributor: fullname: Prausnitz – volume: 158 start-page: 93 year: 2012 end-page: 101 ident: bb0380 article-title: Low temperature fabrication of biodegradable sugar glass microneedles for transdermal drug delivery applications publication-title: J. Control. Release contributor: fullname: Birchall – volume: 154 start-page: 138 year: 2011 end-page: 147 ident: bb0175 article-title: Local transdermal delivery of phenylephrine to the anal sphincter muscle using microneedles publication-title: J. Control. Release contributor: fullname: Park – volume: 390 start-page: 89 year: 2008 end-page: 111 ident: bb0315 article-title: Polymer microfabrication methods for microfluidic devices publication-title: Anal. Bioanal. Chem. contributor: fullname: Gärtner – volume: 147 start-page: 218 year: 2010 end-page: 224 ident: bb0290 article-title: Influence of microneedle shape on the transport of a fluorescent dye into human skin publication-title: J. Control. Release contributor: fullname: Meinke – volume: 1 start-page: 184 year: 2005 end-page: 190 ident: bb0015 article-title: Controlled transdermal delivery of model drug compounds by MEMS microneedle array publication-title: Nanomed. Nanotechnol. Biol. Med. contributor: fullname: Gao – volume: 21 start-page: 569 year: 1966 end-page: 594 ident: bb0400 article-title: Multilayers of colloidal particles publication-title: Adv. Colloid Interface Sci. contributor: fullname: Iler – volume: 28 start-page: 7 year: 2011 end-page: 21 ident: bb0355 article-title: Two-layered dissolving microneedles for percutaneous delivery of peptide/protein drugs in rats publication-title: Pharm. Res. contributor: fullname: Takada – volume: 28 start-page: 95 year: 2011 end-page: 106 ident: bb0160 article-title: Microneedles in clinical practice—an exploratory study into the opinions of healthcare professionals and the public publication-title: Pharm. Res. contributor: fullname: John – volume: 451 start-page: 76 year: 2013 end-page: 91 ident: bb0180 article-title: Hydrogel-forming microneedle arrays exhibit antimicrobial properties: potential for enhanced patient safety publication-title: Int. J. Pharm. contributor: fullname: Woolfson – volume: 163 start-page: 220 year: 2012 end-page: 229 ident: bb0020 article-title: Diclofenac delays micropore closure following microneedle treatment in human subjects publication-title: J. Control. Release contributor: fullname: Stinchcomb – volume: 24 start-page: 585 year: 2008 end-page: 594 ident: bb0095 article-title: Effect of microneedle design on pain in human volunteers publication-title: Clin. J. Pain contributor: fullname: Prausnitz – volume: 149 start-page: 242 year: 2011 end-page: 249 ident: bb0210 article-title: Separable arrowhead microneedles publication-title: J. Control. Release contributor: fullname: Prausnitz – volume: 32 start-page: 3134 year: 2011 end-page: 3140 ident: bb0350 article-title: Dissolving microneedles for transdermal drug administration prepared by stepwise controlled drawing of maltose publication-title: Biomaterials contributor: fullname: Jung – volume: 24 start-page: 1653 year: 2006 end-page: 1664 ident: bb0215 article-title: Effect of delivery parameters on immunization to ovalbumin following intracutaneous administration by a coated microneedle array patch system publication-title: Vaccine contributor: fullname: Cormier – volume: 56 start-page: 581 year: 2004 end-page: 587 ident: bb0085 article-title: Microneedles for transdermal drug delivery publication-title: Adv. Drug Deliv. Rev. contributor: fullname: Prausnitz – volume: 28 start-page: 22 year: 2011 end-page: 30 ident: bb0370 article-title: Transdermal delivery of macromolecules using solid-state biodegradable microstructures publication-title: Pharm. Res. contributor: fullname: Cleary – volume: 170 start-page: 430 year: 2013 end-page: 436 ident: bb0390 article-title: Droplet-born air blowing: novel dissolving microneedle fabrication publication-title: J. Control. Release contributor: fullname: Jung – volume: 117 start-page: 238 year: 2007 end-page: 245 ident: bb0240 article-title: Assembled microneedle arrays enhance the transport of compounds varying over a large range of molecular weight across human dermatomed skin publication-title: J. Control. Release contributor: fullname: Bouwstra – volume: 12 start-page: 855 year: 2003 end-page: 862 ident: bb0265 article-title: Silicon micromachined hollow microneedles for transdermal liquid transport publication-title: J. Microelectromech. Syst. contributor: fullname: van den Berg – volume: 43 start-page: 36 year: 2014 end-page: 68 ident: bb0410 article-title: Layer-by-layer nanoarchitectonics: invention, innovation, and evolution publication-title: Chem. Lett. contributor: fullname: Hill – volume: 161 start-page: 645 year: 2012 end-page: 655 ident: bb0200 article-title: Microneedle technologies for (trans)dermal drug and vaccine delivery publication-title: J. Control. Release contributor: fullname: Bouwstra – volume: 33 start-page: 7309 year: 2012 end-page: 7326 ident: bb0205 article-title: Drawing lithography for microneedles: a review of fundamentals and biomedical applications publication-title: Biomaterials contributor: fullname: Jung – volume: 364 start-page: 227 year: 2008 end-page: 236 ident: bb0030 article-title: Micro-scale devices for transdermal drug delivery publication-title: Int. J. Pharm. contributor: fullname: Mitragotri – volume: 1161 start-page: 83 year: 2009 end-page: 94 ident: bb0050 article-title: Optimizing microneedle arrays to increase skin permeability for transdermal drug publication-title: Ann. N. Y. Acad. Sci. contributor: fullname: Das – start-page: 933 year: 2008 end-page: 938 ident: bb0260 article-title: The use of silicon microfabrication technology publication-title: Minimally invasive protein delivery with rapidly dissolving polymer microneedles contributor: fullname: Subramanian – volume: 56 start-page: 559 year: 2004 end-page: 579 ident: bb0230 article-title: Transdermal delivery with a pressure wave publication-title: Adv. Drug Deliv. Rev. contributor: fullname: Doukas – volume: 139 start-page: 293 year: 2007 end-page: 302 ident: bb0325 article-title: Laser fabrication of high aspect ratio thin holes on biodegradable polymer and its application to a microneedle publication-title: Sens. Actuators A Phys. contributor: fullname: Ogawa – volume: 6 start-page: 1785 year: 2010 end-page: 1793 ident: bb0360 article-title: Targeted, needle-free vaccinations in skin using multi layered, densely-packed dissolving microprojection arrays publication-title: Small contributor: fullname: Kendall – year: 1999 ident: bb0225 article-title: Percutaneous Absorption: Drugs–Cosmetics–Mechanisms–Methodology contributor: fullname: Maibach – volume: 160 start-page: 495 year: 2012 end-page: 501 ident: bb0140 article-title: Transcutaneous immunization using a dissolving microneedle array protects against tetanus, diphtheria, malaria, and influenza publication-title: J. Control. Release contributor: fullname: Nakagawa – volume: 16 start-page: 473 year: 2006 end-page: 479 ident: bb0330 article-title: Sharp bevelled tip hollow microneedle arrays fabricated by LIGA and 3D softlithography with polyvinylalcohol publication-title: J. Micromech. Microeng. contributor: fullname: DiFabrizio – volume: 58 start-page: 68 year: 2006 end-page: 89 ident: bb0075 article-title: Needle-free vaccine delivery publication-title: Adv. Drug Deliv. Rev. contributor: fullname: Campbell – volume: 3 start-page: 115 year: 2004 end-page: 124 ident: bb0010 article-title: Current status and future potential of transdermal drug delivery publication-title: Nat. Rev. Drug Discov. contributor: fullname: Langer – volume: 6 start-page: 8041 year: 2012 end-page: 8051 ident: bb0415 article-title: Releasable layer-by-layer assembly of stabilized lipid nanocapsules on microneedles for enhanced transcutaneous vaccine delivery publication-title: ACS Nano contributor: fullname: Irvine – volume: 29 start-page: 170 year: 2012 end-page: 177 ident: bb0425 article-title: Development of lidocaine-coated microneedle product for rapid safe, and prolonged local analgesic action publication-title: Pharm. Res. contributor: fullname: Hansen – volume: 139 start-page: 212 year: 2009 end-page: 220 ident: bb0155 article-title: Dry-coated microprojection array patches for targeted delivery of immunotherapeutics to the skin publication-title: J. Control. Release contributor: fullname: Kendall – volume: 3 start-page: 1 year: 2006 end-page: 4 ident: bb0070 article-title: Microneedle array technology: the time is right but is the science ready? publication-title: Expert Rev. Med. Devices contributor: fullname: Birchall – year: 2006 ident: bb0435 article-title: Microprojection array patch for transdermal delivery of vascular endothelial growth factors contributor: fullname: Daddona – volume: 333 start-page: 369 year: 2009 end-page: 393 ident: bb0125 article-title: Microneedle-based vaccines publication-title: Curr. Top. Microbiol. Immunol. contributor: fullname: Andrianov – start-page: 494 year: 1998 end-page: 498 ident: bb0255 article-title: Micromachined needles for the transdermal delivery of drugs publication-title: Proceedings: IEEE Micro Electro Mechanical Systems Workshop, 11th, Heidelberg contributor: fullname: Prausnitz – volume: 37 start-page: 1458 year: 1965 end-page: 1461 ident: bb0405 article-title: Porous thin-layer modified glass bead supports for gas liquid chromatography publication-title: Anal. Chem. contributor: fullname: Kirkland – volume: 389 start-page: 122 year: 2010 end-page: 129 ident: bb0300 article-title: Super-short solid silicon microneedles for transdermal drug delivery applications publication-title: Int. J. Pharm. contributor: fullname: Zhang – volume: 166 start-page: 87 year: 2013 end-page: 94 ident: bb0135 article-title: Depth-resolved characterization of diffusion properties within and across minimally-perturbed skin layers publication-title: J. Control. Release contributor: fullname: Kendall – volume: 161 start-page: 933 year: 2012 end-page: 941 ident: bb0395 article-title: The development and characteristics of novel microneedle arrays fabricated from hyaluronic acid, and their application in the transdermal delivery of insulin publication-title: J. Control. Release contributor: fullname: Yamamoto – volume: 112 start-page: 357 year: 2006 end-page: 361 ident: bb0115 article-title: Mechanism of fluid infusion during microneedle insertion and retraction publication-title: J. Control. Release contributor: fullname: Prausnitz – volume: 162 start-page: 529 year: 2012 end-page: 537 ident: bb0055 article-title: Microneedle mediated intradermal delivery of adjuvanted recombinant HIV-1 CN54gp140 effectively primes mucosal boost inoculations publication-title: J. Control. Release contributor: fullname: Donnelly – volume: 117 start-page: 227 year: 2007 end-page: 237 ident: bb0120 article-title: Coated microneedles for transdermal delivery publication-title: J. Control. Release contributor: fullname: Prausnitz – year: 2006 ident: bb0345 article-title: 3-D metal patterned microstructure using inclined UV exposure and metal transfer micromoulding technology publication-title: Solid-State Sensor, Actuator, and Microsystems Workshop contributor: fullname: Allen – volume: 14 start-page: 375 year: 2007 end-page: 381 ident: bb0430 article-title: Preclinical evaluation of microneedle technology for intradermal delivery of influenza vaccines publication-title: Clin. Vaccine Immunol. contributor: fullname: Mikszta – volume: 2 start-page: 110 year: 2009 end-page: 111 ident: bb0295 article-title: Microneedling with dermaroller publication-title: J. Cutan. Aesthet. Surg. contributor: fullname: Doddaballapur – volume: 50 start-page: 609 year: 2013 end-page: 622 ident: bb0045 article-title: Next generation intra-and transdermal therapeutic systems: using non- and minimally-invasive technologies to increase drug delivery into and across the skin publication-title: Eur. J. Pharm. Sci. contributor: fullname: Kalia – volume: 27 start-page: 6932 year: 2009 end-page: 6938 ident: bb0105 article-title: Improved influenza vaccination in the skin using vaccine coated microneedles publication-title: Vaccine contributor: fullname: Prausnitz – volume: 104 start-page: 51 year: 2005 end-page: 66 ident: bb0235 article-title: Biodegradable polymer microneedles: fabrication, mechanics and transdermal drug delivery publication-title: J. Control. Release contributor: fullname: Prausnitz – volume: 98 start-page: 659 year: 2012 end-page: 662 ident: bb0340 article-title: Applying ceramic nanoporous microneedle arrays as a transport interface in egg plants and an ex-vivo human skin model publication-title: Microelectron. Eng. contributor: fullname: Luttge – volume: 26 start-page: 1261 year: 2008 end-page: 1268 ident: bb0080 article-title: Transdermal drug delivery publication-title: Nat. Biotechnol. contributor: fullname: Langer – volume: 56 start-page: 557 year: 2004 end-page: 558 ident: bb0005 article-title: Transdermal drug delivery: past progress, current status, and future prospects publication-title: Adv. Drug Deliv. Rev. contributor: fullname: Langer – volume: 64 start-page: 1547 year: 2012 end-page: 1568 ident: bb0195 article-title: Microneedles for drug and vaccine delivery publication-title: Adv. Drug Deliv. Rev. contributor: fullname: Prausnitz – start-page: 494 year: 1998 ident: 10.1016/j.jconrel.2014.04.052_bb0255 article-title: Micromachined needles for the transdermal delivery of drugs contributor: fullname: Henry – volume: 104 start-page: 51 year: 2005 ident: 10.1016/j.jconrel.2014.04.052_bb0235 article-title: Biodegradable polymer microneedles: fabrication, mechanics and transdermal drug delivery publication-title: J. Control. Release doi: 10.1016/j.jconrel.2005.02.002 contributor: fullname: Park – volume: 50 start-page: 609 year: 2013 ident: 10.1016/j.jconrel.2014.04.052_bb0045 article-title: Next generation intra-and transdermal therapeutic systems: using non- and minimally-invasive technologies to increase drug delivery into and across the skin publication-title: Eur. J. Pharm. Sci. doi: 10.1016/j.ejps.2013.03.019 contributor: fullname: Gratieri – volume: 117 start-page: 227 year: 2007 ident: 10.1016/j.jconrel.2014.04.052_bb0120 article-title: Coated microneedles for transdermal delivery publication-title: J. Control. Release doi: 10.1016/j.jconrel.2006.10.017 contributor: fullname: Gill – volume: 166 start-page: 211 year: 2013 ident: 10.1016/j.jconrel.2014.04.052_bb0040 article-title: Gene silencing following siRNA delivery to skin via coated steel microneedles: in vitro and in vivo proof-of-concept publication-title: J. Control. Release doi: 10.1016/j.jconrel.2012.12.030 contributor: fullname: Chong – volume: 1161 start-page: 83 year: 2009 ident: 10.1016/j.jconrel.2014.04.052_bb0050 article-title: Optimizing microneedle arrays to increase skin permeability for transdermal drug publication-title: Ann. N. Y. Acad. Sci. doi: 10.1111/j.1749-6632.2009.04083.x contributor: fullname: Al-Qallaf – volume: 20 start-page: 45 year: 2008 ident: 10.1016/j.jconrel.2014.04.052_bb0335 article-title: Nickel microneedles fabricated by sequential copper and nickel electroless plating and copper chemical wet etching publication-title: Sens. Mater. contributor: fullname: Jung – volume: 161 start-page: 933 year: 2012 ident: 10.1016/j.jconrel.2014.04.052_bb0395 article-title: The development and characteristics of novel microneedle arrays fabricated from hyaluronic acid, and their application in the transdermal delivery of insulin publication-title: J. Control. Release doi: 10.1016/j.jconrel.2012.05.030 contributor: fullname: Liu – volume: 19 start-page: 63 year: 2002 ident: 10.1016/j.jconrel.2014.04.052_bb0110 article-title: Macroflux microprojection array patch technology: a new and efficient approach for intracutaneous immunization publication-title: Pharm. Res. doi: 10.1023/A:1013607400040 contributor: fullname: Matriano – volume: 2 start-page: 110 year: 2009 ident: 10.1016/j.jconrel.2014.04.052_bb0295 article-title: Microneedling with dermaroller publication-title: J. Cutan. Aesthet. Surg. doi: 10.4103/0974-2077.58529 contributor: fullname: Doddaballapur – volume: 26 start-page: 1261 year: 2008 ident: 10.1016/j.jconrel.2014.04.052_bb0080 article-title: Transdermal drug delivery publication-title: Nat. Biotechnol. doi: 10.1038/nbt.1504 contributor: fullname: Prausnitz – volume: 100 start-page: 13755 year: 2003 ident: 10.1016/j.jconrel.2014.04.052_bb0165 article-title: Microfabricated needles for transdermal delivery of macromolecules and nanoparticles: fabrication methods and transport studies publication-title: PNAS doi: 10.1073/pnas.2331316100 contributor: fullname: McAllister – volume: 29 start-page: 170 year: 2012 ident: 10.1016/j.jconrel.2014.04.052_bb0425 article-title: Development of lidocaine-coated microneedle product for rapid safe, and prolonged local analgesic action publication-title: Pharm. Res. doi: 10.1007/s11095-011-0524-4 contributor: fullname: Zhang – volume: 3 start-page: 1 year: 2006 ident: 10.1016/j.jconrel.2014.04.052_bb0070 article-title: Microneedle array technology: the time is right but is the science ready? publication-title: Expert Rev. Med. Devices doi: 10.1586/17434440.3.1.1 contributor: fullname: Birchall – volume: 24 start-page: 585 year: 2008 ident: 10.1016/j.jconrel.2014.04.052_bb0095 article-title: Effect of microneedle design on pain in human volunteers publication-title: Clin. J. Pain doi: 10.1097/AJP.0b013e31816778f9 contributor: fullname: Gill – volume: 16 start-page: 872 year: 2007 ident: 10.1016/j.jconrel.2014.04.052_bb0285 article-title: Integrated lithographic molding for microneedle-based devices publication-title: J. Microelectromech. Syst. doi: 10.1109/JMEMS.2007.899339 contributor: fullname: Luttge – volume: 33 start-page: 683 year: 2010 ident: 10.1016/j.jconrel.2014.04.052_bb0365 article-title: Self-dissolving micropile array chip as percutaneous delivery system of protein drug publication-title: Biol. Pharm. Bull. doi: 10.1248/bpb.33.683 contributor: fullname: Ito – volume: 28 start-page: 22 year: 2011 ident: 10.1016/j.jconrel.2014.04.052_bb0370 article-title: Transdermal delivery of macromolecules using solid-state biodegradable microstructures publication-title: Pharm. Res. doi: 10.1007/s11095-010-0174-y contributor: fullname: Wendorf – volume: 95 start-page: 151 year: 2010 ident: 10.1016/j.jconrel.2014.04.052_bb0440 article-title: Effect of transdermal teriparatide administration on bone mineral density in postmenopausal women publication-title: J. Clin. Endocrinol. Metab. doi: 10.1210/jc.2009-0358 contributor: fullname: Cosman – start-page: 933 year: 2008 ident: 10.1016/j.jconrel.2014.04.052_bb0260 article-title: The use of silicon microfabrication technology contributor: fullname: Smart – volume: 98 start-page: 659 year: 2012 ident: 10.1016/j.jconrel.2014.04.052_bb0340 article-title: Applying ceramic nanoporous microneedle arrays as a transport interface in egg plants and an ex-vivo human skin model publication-title: Microelectron. Eng. doi: 10.1016/j.mee.2012.07.022 contributor: fullname: Verhoeven – volume: 26 start-page: 2513 year: 2009 ident: 10.1016/j.jconrel.2014.04.052_bb0170 article-title: Microneedle arrays allow lower microbial penetration than hypodermic needles in vitro publication-title: Pharm. Res. doi: 10.1007/s11095-009-9967-2 contributor: fullname: Donnelly – volume: 21 start-page: 569 year: 1966 ident: 10.1016/j.jconrel.2014.04.052_bb0400 article-title: Multilayers of colloidal particles publication-title: Adv. Colloid Interface Sci. doi: 10.1016/0095-8522(66)90018-3 contributor: fullname: Iler – volume: 9 start-page: 223 year: 2007 ident: 10.1016/j.jconrel.2014.04.052_bb0320 article-title: Polymer particle-based micromoulding to fabricate novel microstructures publication-title: Biomed. Microdevices doi: 10.1007/s10544-006-9024-4 contributor: fullname: Park – volume: 29 start-page: 2113 year: 2008 ident: 10.1016/j.jconrel.2014.04.052_bb0385 article-title: Dissolving microneedles for transdermal drug delivery publication-title: Biomaterials doi: 10.1016/j.biomaterials.2007.12.048 contributor: fullname: Lee – volume: 12 start-page: 367 year: 2013 ident: 10.1016/j.jconrel.2014.04.052_bb0420 article-title: Polymer multilayer tattooing for enhanced DNA vaccination publication-title: Nat. Mater. doi: 10.1038/nmat3550 contributor: fullname: DeMuth – volume: 97 start-page: 503 year: 2004 ident: 10.1016/j.jconrel.2014.04.052_bb0220 article-title: Transdermal delivery of desmopressin using a coated microneedle array system publication-title: J. Control. Release doi: 10.1016/j.jconrel.2004.04.003 contributor: fullname: Cormier – volume: 86 start-page: 1196 year: 2008 ident: 10.1016/j.jconrel.2014.04.052_bb0130 article-title: Transdermal drug delivery by coated microneedles: geometry effects on effective skin thickness and drug permeability publication-title: Chem. Eng. Res. Des. doi: 10.1016/j.cherd.2008.06.002 contributor: fullname: Davidson – volume: 390 start-page: 89 year: 2008 ident: 10.1016/j.jconrel.2014.04.052_bb0315 article-title: Polymer microfabrication methods for microfluidic devices publication-title: Anal. Bioanal. Chem. doi: 10.1007/s00216-007-1692-2 contributor: fullname: Becker – volume: 32 start-page: 3134 year: 2011 ident: 10.1016/j.jconrel.2014.04.052_bb0350 article-title: Dissolving microneedles for transdermal drug administration prepared by stepwise controlled drawing of maltose publication-title: Biomaterials doi: 10.1016/j.biomaterials.2011.01.014 contributor: fullname: Lee – volume: 3 start-page: 115 year: 2004 ident: 10.1016/j.jconrel.2014.04.052_bb0010 article-title: Current status and future potential of transdermal drug delivery publication-title: Nat. Rev. Drug Discov. doi: 10.1038/nrd1304 contributor: fullname: Prausnitz – volume: 147 start-page: 218 year: 2010 ident: 10.1016/j.jconrel.2014.04.052_bb0290 article-title: Influence of microneedle shape on the transport of a fluorescent dye into human skin in vivo publication-title: J. Control. Release doi: 10.1016/j.jconrel.2010.07.104 contributor: fullname: Bal – volume: 166 start-page: 87 year: 2013 ident: 10.1016/j.jconrel.2014.04.052_bb0135 article-title: Depth-resolved characterization of diffusion properties within and across minimally-perturbed skin layers publication-title: J. Control. Release doi: 10.1016/j.jconrel.2012.12.010 contributor: fullname: Raphael – volume: 28 start-page: 95 year: 2011 ident: 10.1016/j.jconrel.2014.04.052_bb0160 article-title: Microneedles in clinical practice—an exploratory study into the opinions of healthcare professionals and the public publication-title: Pharm. Res. doi: 10.1007/s11095-010-0101-2 contributor: fullname: Birchall – volume: 51 start-page: 964 year: 2011 ident: 10.1016/j.jconrel.2014.04.052_bb0060 article-title: Microneedles: a valuable physical enhancer to increase transdermal drug delivery publication-title: J. Clin. Pharmacol. doi: 10.1177/0091270010378859 contributor: fullname: Escobar-Chávez – volume: 139 start-page: 212 year: 2009 ident: 10.1016/j.jconrel.2014.04.052_bb0155 article-title: Dry-coated microprojection array patches for targeted delivery of immunotherapeutics to the skin publication-title: J. Control. Release doi: 10.1016/j.jconrel.2009.06.029 contributor: fullname: Chen – volume: 14 start-page: 375 year: 2007 ident: 10.1016/j.jconrel.2014.04.052_bb0430 article-title: Preclinical evaluation of microneedle technology for intradermal delivery of influenza vaccines publication-title: Clin. Vaccine Immunol. doi: 10.1128/CVI.00387-06 contributor: fullname: Alarcon – volume: 451 start-page: 76 year: 2013 ident: 10.1016/j.jconrel.2014.04.052_bb0180 article-title: Hydrogel-forming microneedle arrays exhibit antimicrobial properties: potential for enhanced patient safety publication-title: Int. J. Pharm. doi: 10.1016/j.ijpharm.2013.04.045 contributor: fullname: Donnelly – ident: 10.1016/j.jconrel.2014.04.052_bb0250 – volume: 43 start-page: 36 year: 2014 ident: 10.1016/j.jconrel.2014.04.052_bb0410 article-title: Layer-by-layer nanoarchitectonics: invention, innovation, and evolution publication-title: Chem. Lett. doi: 10.1246/cl.130987 contributor: fullname: Ariga – volume: 11 start-page: 35 year: 2009 ident: 10.1016/j.jconrel.2014.04.052_bb0100 article-title: Clinical administration of microneedles: skin puncture, pain and sensation publication-title: Biomed. Microdevices doi: 10.1007/s10544-008-9208-1 contributor: fullname: Haq – volume: 4 start-page: 19 year: 2007 ident: 10.1016/j.jconrel.2014.04.052_bb0190 article-title: Microneedles and transdermal applications publication-title: Expert Opin. Drug Deliv. doi: 10.1517/17425247.4.1.19 contributor: fullname: Sivamani – volume: 7 start-page: 47 year: 2005 ident: 10.1016/j.jconrel.2014.04.052_bb0270 article-title: In vitro and in vivo characterization of MEMS microneedles publication-title: Biomed. Microdevices doi: 10.1007/s10544-005-6171-y contributor: fullname: Teo – volume: 33 start-page: 7309 year: 2012 ident: 10.1016/j.jconrel.2014.04.052_bb0205 article-title: Drawing lithography for microneedles: a review of fundamentals and biomedical applications publication-title: Biomaterials doi: 10.1016/j.biomaterials.2012.06.065 contributor: fullname: Lee – volume: 5 start-page: 95 year: 2011 ident: 10.1016/j.jconrel.2014.04.052_bb0090 article-title: Microneedles and their applications publication-title: Recent Pat. Drug Deliv. Formul. doi: 10.2174/187221111795471445 contributor: fullname: Sachdeva – volume: 139 start-page: 293 year: 2007 ident: 10.1016/j.jconrel.2014.04.052_bb0325 article-title: Laser fabrication of high aspect ratio thin holes on biodegradable polymer and its application to a microneedle publication-title: Sens. Actuators A Phys. doi: 10.1016/j.sna.2006.11.022 contributor: fullname: Aoyagi – year: 2006 ident: 10.1016/j.jconrel.2014.04.052_bb0345 article-title: 3-D metal patterned microstructure using inclined UV exposure and metal transfer micromoulding technology contributor: fullname: Choi – volume: 64 start-page: 1547 year: 2012 ident: 10.1016/j.jconrel.2014.04.052_bb0195 article-title: Microneedles for drug and vaccine delivery publication-title: Adv. Drug Deliv. Rev. doi: 10.1016/j.addr.2012.04.005 contributor: fullname: Kim – year: 1999 ident: 10.1016/j.jconrel.2014.04.052_bb0225 contributor: fullname: Bronaugh – volume: 56 start-page: 559 year: 2004 ident: 10.1016/j.jconrel.2014.04.052_bb0230 article-title: Transdermal delivery with a pressure wave publication-title: Adv. Drug Deliv. Rev. doi: 10.1016/j.addr.2003.10.031 contributor: fullname: Doukas – volume: 28 start-page: 7 year: 2011 ident: 10.1016/j.jconrel.2014.04.052_bb0355 article-title: Two-layered dissolving microneedles for percutaneous delivery of peptide/protein drugs in rats publication-title: Pharm. Res. doi: 10.1007/s11095-010-0097-7 contributor: fullname: Fukushima – volume: 159 start-page: 34 year: 2012 ident: 10.1016/j.jconrel.2014.04.052_bb0145 article-title: Coated microneedle arrays for transcutaneous delivery of live virus vaccines publication-title: J. Control. Release doi: 10.1016/j.jconrel.2011.12.026 contributor: fullname: Vrdoljak – volume: 136 start-page: 71 year: 2009 ident: 10.1016/j.jconrel.2014.04.052_bb0150 article-title: Microneedle arrays for the transcutaneous immunization of diphtheria and influenza in BALB/c mice publication-title: J. Control. Release doi: 10.1016/j.jconrel.2009.01.025 contributor: fullname: Ding – volume: 112 start-page: 357 year: 2006 ident: 10.1016/j.jconrel.2014.04.052_bb0115 article-title: Mechanism of fluid infusion during microneedle insertion and retraction publication-title: J. Control. Release doi: 10.1016/j.jconrel.2006.02.017 contributor: fullname: Martanto – volume: 160 start-page: 495 year: 2012 ident: 10.1016/j.jconrel.2014.04.052_bb0140 article-title: Transcutaneous immunization using a dissolving microneedle array protects against tetanus, diphtheria, malaria, and influenza publication-title: J. Control. Release doi: 10.1016/j.jconrel.2012.04.001 contributor: fullname: Matsuo – volume: 24 start-page: 1653 year: 2006 ident: 10.1016/j.jconrel.2014.04.052_bb0215 article-title: Effect of delivery parameters on immunization to ovalbumin following intracutaneous administration by a coated microneedle array patch system publication-title: Vaccine doi: 10.1016/j.vaccine.2005.09.049 contributor: fullname: Widera – year: 2006 ident: 10.1016/j.jconrel.2014.04.052_bb0435 contributor: fullname: Ameri – volume: 31 start-page: 1632 year: 2011 ident: 10.1016/j.jconrel.2014.04.052_bb0375 article-title: Rapidly dissolving fibroin microneedles for transdermal drug delivery publication-title: Mater. Sci. Eng. C doi: 10.1016/j.msec.2011.06.010 contributor: fullname: You – volume: 333 start-page: 369 year: 2009 ident: 10.1016/j.jconrel.2014.04.052_bb0125 article-title: Microneedle-based vaccines publication-title: Curr. Top. Microbiol. Immunol. contributor: fullname: Prausnitz – volume: 16 start-page: 473 year: 2006 ident: 10.1016/j.jconrel.2014.04.052_bb0330 article-title: Sharp bevelled tip hollow microneedle arrays fabricated by LIGA and 3D softlithography with polyvinylalcohol publication-title: J. Micromech. Microeng. doi: 10.1088/0960-1317/16/3/001 contributor: fullname: Perennes – volume: 1 start-page: 184 year: 2005 ident: 10.1016/j.jconrel.2014.04.052_bb0015 article-title: Controlled transdermal delivery of model drug compounds by MEMS microneedle array publication-title: Nanomed. Nanotechnol. Biol. Med. doi: 10.1016/j.nano.2005.03.001 contributor: fullname: Xie – volume: 16 start-page: 1061 year: 2011 ident: 10.1016/j.jconrel.2014.04.052_bb0065 article-title: Recent advances in the administration of vaccines for infectious diseases: microneedles as painless delivery devices for mass vaccination publication-title: Drug Discov. Today doi: 10.1016/j.drudis.2011.07.004 contributor: fullname: Hedge – volume: 13 start-page: 1711 year: 2008 ident: 10.1016/j.jconrel.2014.04.052_bb0245 article-title: Microneedles for transdermal drug delivery: a mini review publication-title: Front. Biosci. doi: 10.2741/2794 contributor: fullname: Vandervoort – volume: 163 start-page: 220 year: 2012 ident: 10.1016/j.jconrel.2014.04.052_bb0020 article-title: Diclofenac delays micropore closure following microneedle treatment in human subjects publication-title: J. Control. Release doi: 10.1016/j.jconrel.2012.08.015 contributor: fullname: Brogden – volume: 162 start-page: 529 year: 2012 ident: 10.1016/j.jconrel.2014.04.052_bb0055 article-title: Microneedle mediated intradermal delivery of adjuvanted recombinant HIV-1 CN54gp140 effectively primes mucosal boost inoculations publication-title: J. Control. Release doi: 10.1016/j.jconrel.2012.07.039 contributor: fullname: Pattani – volume: 64 start-page: 1603 year: 2012 ident: 10.1016/j.jconrel.2014.04.052_bb0310 article-title: Polymeric microdevices for transdermal and subcutaneous drug delivery publication-title: Adv. Drug Deliv. Rev. doi: 10.1016/j.addr.2012.09.035 contributor: fullname: Ochoa – volume: 37 start-page: 1458 year: 1965 ident: 10.1016/j.jconrel.2014.04.052_bb0405 article-title: Porous thin-layer modified glass bead supports for gas liquid chromatography publication-title: Anal. Chem. doi: 10.1021/ac60231a004 contributor: fullname: Kirkland – volume: 56 start-page: 557 year: 2004 ident: 10.1016/j.jconrel.2014.04.052_bb0005 article-title: Transdermal drug delivery: past progress, current status, and future prospects publication-title: Adv. Drug Deliv. Rev. doi: 10.1016/j.addr.2003.10.021 contributor: fullname: Langer – volume: 58 start-page: 68 year: 2006 ident: 10.1016/j.jconrel.2014.04.052_bb0075 article-title: Needle-free vaccine delivery publication-title: Adv. Drug Deliv. Rev. doi: 10.1016/j.addr.2005.12.003 contributor: fullname: Giudice – volume: 56 start-page: 603 year: 2004 ident: 10.1016/j.jconrel.2014.04.052_bb0025 article-title: Penetration enhancers publication-title: Adv. Drug Deliv. Rev. doi: 10.1016/j.addr.2003.10.025 contributor: fullname: Williams – volume: 52 start-page: 909 year: 2005 ident: 10.1016/j.jconrel.2014.04.052_bb0275 article-title: Hollow metal microneedles for insulin delivery to diabetic rats publication-title: IEEE Trans. Biomed. Eng. doi: 10.1109/TBME.2005.845240 contributor: fullname: Davis – volume: 364 start-page: 227 year: 2008 ident: 10.1016/j.jconrel.2014.04.052_bb0030 article-title: Micro-scale devices for transdermal drug delivery publication-title: Int. J. Pharm. doi: 10.1016/j.ijpharm.2008.08.032 contributor: fullname: Arora – start-page: 46 year: 2005 ident: 10.1016/j.jconrel.2014.04.052_bb0035 article-title: Breaking the barrier: advances in transdermal technology publication-title: Pharm. Technol. contributor: fullname: Chiarello – volume: 27 start-page: 6932 year: 2009 ident: 10.1016/j.jconrel.2014.04.052_bb0105 article-title: Improved influenza vaccination in the skin using vaccine coated microneedles publication-title: Vaccine doi: 10.1016/j.vaccine.2009.08.108 contributor: fullname: Kim – volume: 6 start-page: 1785 year: 2010 ident: 10.1016/j.jconrel.2014.04.052_bb0360 article-title: Targeted, needle-free vaccinations in skin using multi layered, densely-packed dissolving microprojection arrays publication-title: Small doi: 10.1002/smll.201000326 contributor: fullname: Raphael – volume: 86 start-page: 267 year: 2014 ident: 10.1016/j.jconrel.2014.04.052_bb0185 article-title: Transdermal delivery of relatively high molecular weight drugs using novel self-dissolving microneedle arrays fabricated from hyaluronic acid and their characteristics and safety after application to the skin publication-title: Eur. J. Pharm. Biopharm. doi: 10.1016/j.ejpb.2013.10.001 contributor: fullname: Liu – volume: 158 start-page: 93 year: 2012 ident: 10.1016/j.jconrel.2014.04.052_bb0380 article-title: Low temperature fabrication of biodegradable sugar glass microneedles for transdermal drug delivery applications publication-title: J. Control. Release doi: 10.1016/j.jconrel.2011.10.024 contributor: fullname: Martin – volume: 12 start-page: 855 year: 2003 ident: 10.1016/j.jconrel.2014.04.052_bb0265 article-title: Silicon micromachined hollow microneedles for transdermal liquid transport publication-title: J. Microelectromech. Syst. doi: 10.1109/JMEMS.2003.820293 contributor: fullname: Gardeniers – volume: 23 start-page: 1008 year: 2006 ident: 10.1016/j.jconrel.2014.04.052_bb0280 article-title: Polymer microneedles for controlled-release drug delivery publication-title: Pharm. Res. doi: 10.1007/s11095-006-0028-9 contributor: fullname: Park – volume: 389 start-page: 122 year: 2010 ident: 10.1016/j.jconrel.2014.04.052_bb0300 article-title: Super-short solid silicon microneedles for transdermal drug delivery applications publication-title: Int. J. Pharm. doi: 10.1016/j.ijpharm.2010.01.024 contributor: fullname: Li – volume: 56 start-page: 581 year: 2004 ident: 10.1016/j.jconrel.2014.04.052_bb0085 article-title: Microneedles for transdermal drug delivery publication-title: Adv. Drug Deliv. Rev. doi: 10.1016/j.addr.2003.10.023 contributor: fullname: Prausnitz – volume: 88 start-page: 1681 year: 2011 ident: 10.1016/j.jconrel.2014.04.052_bb0305 article-title: Micromoulding for ceramic microneedle arrays publication-title: Microelectron. Eng. doi: 10.1016/j.mee.2010.12.067 contributor: fullname: Bystrova – volume: 154 start-page: 138 year: 2011 ident: 10.1016/j.jconrel.2014.04.052_bb0175 article-title: Local transdermal delivery of phenylephrine to the anal sphincter muscle using microneedles publication-title: J. Control. Release doi: 10.1016/j.jconrel.2011.05.004 contributor: fullname: Baek – volume: 149 start-page: 242 year: 2011 ident: 10.1016/j.jconrel.2014.04.052_bb0210 article-title: Separable arrowhead microneedles publication-title: J. Control. Release doi: 10.1016/j.jconrel.2010.10.033 contributor: fullname: Chu – volume: 117 start-page: 238 year: 2007 ident: 10.1016/j.jconrel.2014.04.052_bb0240 article-title: Assembled microneedle arrays enhance the transport of compounds varying over a large range of molecular weight across human dermatomed skin publication-title: J. Control. Release doi: 10.1016/j.jconrel.2006.11.009 contributor: fullname: Verbaan – volume: 170 start-page: 430 year: 2013 ident: 10.1016/j.jconrel.2014.04.052_bb0390 article-title: Droplet-born air blowing: novel dissolving microneedle fabrication publication-title: J. Control. Release doi: 10.1016/j.jconrel.2013.05.026 contributor: fullname: Kim – volume: 6 start-page: 8041 year: 2012 ident: 10.1016/j.jconrel.2014.04.052_bb0415 article-title: Releasable layer-by-layer assembly of stabilized lipid nanocapsules on microneedles for enhanced transcutaneous vaccine delivery publication-title: ACS Nano doi: 10.1021/nn302639r contributor: fullname: DeMuth – volume: 161 start-page: 645 year: 2012 ident: 10.1016/j.jconrel.2014.04.052_bb0200 article-title: Microneedle technologies for (trans)dermal drug and vaccine delivery publication-title: J. Control. Release doi: 10.1016/j.jconrel.2012.01.042 contributor: fullname: van der Maaden
SSID	ssj0005347
Score	2.6270764
SecondaryResourceType	review_article
Snippet	The transdermal route is an excellent site for drug delivery due to the avoidance of gastric degradation and hepatic metabolism, in addition to easy...
SourceID	proquest crossref pubmed elsevier
SourceType	Aggregation Database Index Database Publisher
StartPage	130
SubjectTerms	Administration, Cutaneous Animals Drug Delivery Systems - instrumentation Equipment Design Humans Hypodermic Microinjections - instrumentation Microneedle Microscale fabrication techniques Needles Pharmaceutical Preparations - administration & dosage
Title	Current advances in the fabrication of microneedles for transdermal delivery
URI	https://dx.doi.org/10.1016/j.jconrel.2014.04.052 https://www.ncbi.nlm.nih.gov/pubmed/24806483 https://search.proquest.com/docview/1544000293 https://search.proquest.com/docview/1548640151
Volume	185
hasFullText	1
inHoldings	1
isFullTextHit
isPrint
link	http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3da9swEBdp-7KXsXVfWdehwehL6iy2JFt-LJ1HO8YIawbdk5EtiS5kTonjh_z3PVlS7XbtvmAQTCKSWLm7nO7jd3cIvaWiACsBOKBDKgI4IUjAuS4CLuiEmGk5um2xcXKWfD7n7zOaDQZ-aka39l85DWvAa1M5-xfcvv5SWIDnwHO4Atfh-kd89w2XXHK_9kBGLYqVi8-1OXUDxKvg6Fqo2kINzaEljZ5ejKRaGLjGjYxvz3J18PaFku3IlV5-59SUyvxobEy1qYSbzd0ifpr12o5x_9LOguhwBUtwBtppR6Nv4mIjRtm4yy85_Pd0JaRSl_0QRUhN7NOBVdu42U-1MzaUGfOAxK4fuLLqlyckAB-M3dTPrKdhQ5fGUe4Vv_McsCGJ-XgOFAFKGAgfbVva2na5t1psn5m9mK2Atwn2FmNbaCcCxQV6c-foNDv_2IGGCLUF-G7vXU3Yuztvdp-1c58301o1s0fooWMqPrJy9BgNVLWLDqa2n_nmEM-68rz6EB_gadfpfPMEfXLChr2w4e8VBmHDPWHDS437woZB2HBP2LAXtqfo64dsdnwSuPEcQQlW-joohUy0EMlEMPj9kogoAns1ipOSpWVEFLhtMiWsUAWnuhSaRLwMdVwUoBuIaUP0DG1XcPMXCKcqSaQqZME0uBglFSyVoaZUah2ZUpMhGnsy5pe2C0vu4Ynz3NE9N3TPJ_Bg0RBxT-zcmZLWRMxBQn730TeeOTmoWpM_E5VaNnVuGlcZCyIlv3wPjynY2OEQPbecvd5xRDk4AJy8_PfN7aEH3R_sFdperxq1j7Zq2bx2onoFcBa7Fg
link.rule.ids	315,782,786,27933,27934
linkProvider	Elsevier
openUrl	ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Current+advances+in+the+fabrication+of+microneedles+for+transdermal+delivery&rft.jtitle=Journal+of+controlled+release&rft.au=Indermun%2C+Sunaina&rft.au=Luttge%2C+Regina&rft.au=Choonara%2C+Yahya+E.&rft.au=Kumar%2C+Pradeep&rft.date=2014-07-10&rft.pub=Elsevier+B.V&rft.issn=0168-3659&rft.eissn=1873-4995&rft.volume=185&rft.spage=130&rft.epage=138&rft_id=info:doi/10.1016%2Fj.jconrel.2014.04.052&rft.externalDocID=S0168365914002855
thumbnail_l	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0168-3659&client=summon
thumbnail_m	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0168-3659&client=summon
thumbnail_s	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0168-3659&client=summon