Validation study of a noninvasive urine test for diagnosis and prognosis assessment of bladder cancer: evidence for improved models

We validated the performance of our previously reported test for bladder cancer based on urine gene expression patterns using an independent cohort. We also ascertained whether alternative models could achieve better accuracy. Gene expression patterns of the previously reported 48 genes, including t...

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Bibliographic Details
Published in:	The Journal of urology Vol. 191; no. 1; p. 261
Main Authors:	Mengual, Lourdes, Ribal, María José, Lozano, Juan José, Ingelmo-Torres, Mercedes, Burset, Moisés, Fernández, Pedro Luís, Alcaraz, Antonio
Format:	Journal Article
Language:	English
Published:	United States 01-01-2014
Subjects:	Biomarkers, Tumor - urine Humans Prognosis Transcriptome Urinary Bladder Neoplasms - diagnosis Urinary Bladder Neoplasms - genetics Urinary Bladder Neoplasms - urine carcinoma in situ NMIBC low grade LOOCV Cq muscle invasive bladder cancer leave-one-out cross validation specificity urothelial cell carcinoma SN SP high grade polymerase chain reaction nonMIBC urinary bladder CIS urothelium cycle quantification UCC carcinoma biological markers MIBC LG sensitivity PCR gene expression HG
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