Reproductive axis function and gonadotropin microheterogeneity in a male rat model of diet-induced obesity

Abstract Obesity causes complex metabolic and endocrine changes that may lead to adverse outcomes, including hypogonadism. We herein studied the reproductive axis function in male rats under a high-fat diet and analyzed the impact of changes in glycosylation of pituitary LH on the bioactivity of thi...

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Bibliographic Details
Published in:	General and comparative endocrinology Vol. 166; no. 2; pp. 356 - 364
Main Authors:	Olivares, Aleida, Méndez, Juan Pablo, Zambrano, Elena, Cárdenas, Mario, Tovar, Armando, Perera-Marín, Gerardo, Ulloa-Aguirre, Alfredo
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01-04-2010
Subjects:	Animals Blood Glucose - analysis Dietary Fats - administration & dosage Disease Models, Animal Endocrinology & Metabolism Estradiol - blood Experimental obesity Glycosylation High-fat diet Hydrogen-Ion Concentration Insulin Resistance Leptin - blood LH bioactivity Luteinizing hormone Luteinizing Hormone - analysis Luteinizing Hormone - blood Luteinizing Hormone - physiology Male Metabolic Syndrome Obesity - etiology Obesity - physiopathology Pituitary Gland, Anterior - chemistry Protein Isoforms - analysis Rats Rats, Wistar Reproduction - physiology Testosterone - blood Triglycerides - blood Luteinizing hormone LH bioactivity High-fat diet Experimental obesity
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