White matter abnormalities and brain activation in schizophrenia: A combined DTI and fMRI study

Abstract Diffusion tensor imaging (DTI) studies of schizophrenia have revealed white matter abnormalities in several areas of the brain. The functional impact on either psychopathology or cognition remains, however, poorly understood. Here we analysed both functional MRI (during a working memory tas...

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Bibliographic Details
Published in:	Schizophrenia research Vol. 89; no. 1; pp. 1 - 11
Main Authors:	Schlösser, Ralf G.M, Nenadic, Igor, Wagner, Gerd, Güllmar, Daniel, von Consbruch, Katrin, Köhler, Sabine, Schultz, C. Christoph, Koch, Kathrin, Fitzek, Clemens, Matthews, Paul M, Reichenbach, Jürgen R, Sauer, Heinrich
Format:	Journal Article
Language:	English
Published:	Amsterdam Elsevier B.V 01-01-2007 Elsevier Science
Subjects:	Adult Adult and adolescent clinical studies Anisotropy Arousal - physiology Biological and medical sciences Brain - pathology Brain - physiopathology Brain Mapping Cerebral Cortex - pathology Cerebral Cortex - physiopathology Cingulum Cognition Diffusion Magnetic Resonance Imaging Diffusion tensor imaging (DTI) Dominance, Cerebral - physiology Female Functional magnetic resonance imaging (fMRI) Gyrus Cinguli - pathology Gyrus Cinguli - physiopathology Hippocampus Hippocampus - pathology Hippocampus - physiopathology Humans Image Processing, Computer-Assisted Imaging, Three-Dimensional Magnetic Resonance Imaging Male Medial temporal lobe Medical sciences Memory, Short-Term - physiology Nerve Fibers, Myelinated - physiology Nerve Net - pathology Nerve Net - physiopathology Parahippocampal gyrus Parahippocampal Gyrus - pathology Parahippocampal Gyrus - physiopathology Prefrontal cortex Prefrontal Cortex - pathology Prefrontal Cortex - physiopathology Problem Solving - physiology Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses Schizophrenia Schizophrenia - diagnosis Schizophrenia - physiopathology Schizophrenic Psychology Serial Learning - physiology Temporal Lobe - pathology Temporal Lobe - physiopathology Schizophrenia Cingulum Cognition Functional magnetic resonance imaging (fMRI) Prefrontal cortex Parahippocampal gyrus Diffusion tensor imaging (DTI) Hippocampus Medial temporal lobe Human Temporal lobe Parahippocampal gyms Central nervous system Activation Nuclear magnetic resonance imaging White matter Encephalon Diffusion tensor imaging Psychosis Medical imagery Functional imaging
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