Selective Induction of Mitochondrial Chaperones in Response to Loss of the Mitochondrial Genome

Molecular chaperones are known to play key roles in the synthesis, transport and folding of nuclear‐encoded mitochondrial proteins and of proteins encoded by mitochondrial DNA. Although the regulation of heat‐shock genes has been the subject of considerable investigation, regulation of the genes enc...

Full description

Saved in:

Bibliographic Details
Published in:	European journal of biochemistry Vol. 240; no. 1; pp. 98 - 103
Main Authors:	Martinus, Ryan D., Garth, Graeme P., Webster, Tracie L., Cartwright, Peter, Naylor, Dean J., Høj, Peter B., Hoogenraad, Nicholas J.
Format:	Journal Article
Language:	English
Published:	Oxford, UK Blackwell Publishing Ltd 01-08-1996
Subjects:	Animals Blotting, Western Cell Nucleus - metabolism Clone Cells Cytosol - metabolism DNA, Mitochondrial - drug effects DNA, Mitochondrial - genetics DNA, Mitochondrial - metabolism DNA, Neoplasm - drug effects DNA, Neoplasm - genetics DNA, Neoplasm - metabolism Ethidium - pharmacology Fluorescent Antibody Technique, Indirect gene activation heat shock Heat-Shock Proteins - biosynthesis Hot Temperature HSP70 Heat-Shock Proteins - biosynthesis HSP72 Heat-Shock Proteins Liver Neoplasms, Experimental mitochondria Mitochondria - drug effects Mitochondria - metabolism molecular chaperone Molecular Chaperones - biosynthesis Polymerase Chain Reaction Pyruvic Acid - pharmacology Rats stress response Transcription, Genetic Uridine - metabolism Uridine - pharmacology
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!