CAR‐NK cell in cancer immunotherapy; A promising frontier

Chimeric antigen receptors (CARs) have a unique facet of synthetic biology and offer a paradigm shift in personalized medicine as they can use and redirect the patient's immune cells to attack cancer cells. CAR‐natural killer (NK) cells combine the targeted specificity of antigens with the subs...

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Bibliographic Details
Published in:	Cancer science Vol. 112; no. 9; pp. 3427 - 3436
Main Authors:	Marofi, Faroogh, Abdul‐Rasheed, Omar F., Rahman, Heshu Sulaiman, Budi, Hendrik Setia, Jalil, Abduladheem Turki, Yumashev, Alexei Valerievich, Hassanzadeh, Ali, Yazdanifar, Mahboubeh, Motavalli, Roza, Chartrand, Max Stanley, Ahmadi, Majid, Cid‐Arreguid, Angel, Jarahian, Mostafa
Format:	Journal Article
Language:	English
Published:	Tokyo John Wiley & Sons, Inc 01-09-2021 John Wiley and Sons Inc
Subjects:	Antibodies Antigen (tumor-associated) Antigens Apoptosis Cancer Cancer immunotherapy Care and treatment CAR‐NK Cell growth Cell proliferation Chemokines Chimeric antigen receptors Cytokines Cytotoxicity Dendritic cells Development and progression Effector cells Health aspects Histocompatibility antigen HLA Histocompatibility antigens HLA histocompatibility antigens Immunotherapy Intracellular signalling Killer cells Ligands Lymphocytes Metastases Natural killer cells Precision medicine Review Signal transduction Solid tumors Tumor microenvironment Tumor necrosis factor-TNF Tumors
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