Effects of hormonal contraceptives on sleep - A possible treatment for insomnia in premenopausal women

• Published in: Sleep science (São Paulo, SP ) Vol. 11; no. 3; pp. 129 - 136
• Main Authors: Bezerra, Andreia Gomes, Andersen, Monica Levy, Pires, Gabriel Natan, Tufik, Sergio, Hachul, Helena
• Format: Journal Article
• Language: English
• Published: Brazilian Association of Sleep and Latin American Federation of Sleep 01-01-2018; Thieme Revinter Publicações Ltda
• Subjects: Contraceptives; Estrogen; GABA; Insomnia; Progestagen; Sleep; Theoretical s
• ISSN: 1984-0659; 1984-0063
• DOI: 10.5935/1984-0063.20180025

Due to the changes that took place since the 1970s, women have achieved important socioeconomic positions. Many tasks, including domestic and familiar ones, continue to be under women’s responsibility, which leads to an overload work. Additionally, the female organism has its peculiarities due to hormonal changes. Adding all these factors up, women seem to be more vulnerable to stressing factors and consequently, might be prone to present several health problems. Within this scenario, one can point out insomnia as a highly prevalent disease among women, directly affecting performance and quality of life. Progesterone has an important effect over sleep, acting both as a hypnogenic and as a respiratory stimulant. Hormonal contraceptives are largely recognized among the modern society women; however, little is known about the effects of these drugs on sleep. This proposal hypothesizes that the use of hormonal contraceptives, mainly those based on progestagens could be a new therapeutic element for the treatment of insomnia and one more tool to be used to improve women´s sleep pattern and quality of life.