Development of SiC–TiO2-Graphene neem extracted antimicrobial nano membrane for enhancement of multiphysical properties and future prospect in dental implant applications

• Published in: Heliyon Vol. 8; no. 9; p. e10603
• Main Authors: Chowdhury, Mohammad Asaduzzaman, Hossain, Nayem, Shahid, Md. Abdus, Alam, Md. Jonaidul, Hossain, Sheikh Monir, Uddin, Md. Ilias, Rana, Md. Masud
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01-09-2022; Elsevier
• Subjects: Antimicrobial activity; Cytotoxicity; Nano membrane; Neem; PVA; Nano membrane; Cytotoxicity; Antimicrobial activity; PVA; Neem
• ISSN: 2405-8440; 2405-8440
• DOI: 10.1016/j.heliyon.2022.e10603

This paper presents the coating technology on Nano membrane using SiC–TiO2-Graphene with varying percentages of Azadirachta indica (Neem) extract with an objective to develop new coating materials. The nanomembranes have been synthesized by electrospinning machine over aluminum foil paper using the raw materials PVA grain, SiC, TiO2, Graphene, and neem. The nanomembranes have been characterized by SEM, XRD, FTIR, Surface Roughness, antibacterial, and Cytotoxicity test. FTIR analysis established the presence of PVA and neem indicating the formation of different organic compounds. It also confirmed that no chemical reaction occurred during the synthesis process. The membrane's roughness analysis obtained average roughness values from 1.15 to 3.84. The formation of homogeneous and smooth membranes with the formation of micropores was confirmed by SEM analysis. Miller Indices identified different types of crystal structures in XRD analysis. Antibacterial activity increased with the increase of the percentage of neem confirmed by the antibacterial test. No toxic effects were observed from the membrane during the cytotoxicity test. The obtained data confirmed that the synthesized nanomembrane could be used in different biomedical applications.
•Synthesis of Nano membrane using SiC–TiO2-GRAPHENE with varying percentages of Azadirachta indica.•Synthesis by electrospinning machine.•Increased antibacterial activity.•Characterized by SEM, XRD, FTIR, Surface Roughness, Antibacterial and Cytotoxicity test.
Nano membrane; Neem; PVA; Antimicrobial activity; Cytotoxicity.