Antiviral activity of betulin, betulinic and betulonic acids against some enveloped and non-enveloped viruses

Antiviral properties of betulin, betulinic and betulonic acids were investigated in cell cultures infected with herpes simplex type I, influenza FPV/Rostock and ECHO 6 viruses. All studied triterpenes were active against herpes simplex virus. Betulin and especially betulinic acid also suppressed ECH...

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Bibliographic Details
Published in:	Fitoterapia Vol. 74; no. 5; pp. 489 - 492
Main Authors:	Pavlova, N.I., Savinova, O.V., Nikolaeva, S.N., Boreko, E.I., Flekhter, O.B.
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01-07-2003
Subjects:	Antiviral activity Antiviral Agents - administration & dosage Antiviral Agents - pharmacology Antiviral Agents - therapeutic use Betulin Betulinic acid Betulonic acid Dose-Response Relationship, Drug Echovirus 6, Human - drug effects Herpesvirus 1, Human - drug effects Humans Influenza A virus - drug effects Microbial Sensitivity Tests Oleanolic Acid - administration & dosage Oleanolic Acid - analogs & derivatives Oleanolic Acid - pharmacology Oleanolic Acid - therapeutic use Phytotherapy Plant Bark Plant Extracts - administration & dosage Plant Extracts - pharmacology Plant Extracts - therapeutic use Triterpenes - administration & dosage Triterpenes - pharmacology Triterpenes - therapeutic use Tumor Cells, Cultured - drug effects Viral Envelope Proteins Betulin Betulinic acid Betulonic acid Antiviral activity
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