Molecular, cellular, and functional characterization of chicken cytokines homologous to mammalian IL-15 and IL-2

DNA sequence analysis of a chicken interleukin (IL)-15 cDNA identified a 187 amino acid open reading frame encoding a protein with a predicted molecular weight of 21,964 Da, two potential N-linked glycosylation sites, four highly conserved Cys residues, two out-of-frame AUG initiation codons in the...

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Bibliographic Details
Published in:	Veterinary immunology and immunopathology Vol. 82; no. 3; pp. 229 - 244
Main Authors:	Lillehoj, Hyun Soon, Min, Wongi, Choi, Kang Duk, Babu, Uma S., Burnside, Joan, Miyamoto, Tadashi, Rosenthal, Benjamin M., Lillehoj, Erik P.
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01-10-2001
Subjects:	Amino Acid Sequence Animals Base Sequence Blotting, Northern Cell Division - immunology Cercopithecus aethiops Chickens Chickens - genetics Chickens - immunology Cloning, Molecular COS Cells Cytokine Escherichia coli - genetics Flow Cytometry Gene Expression Regulation Interleukin-15 Interleukin-15 - genetics Interleukin-15 - immunology Interleukin-2 Interleukin-2 - genetics Interleukin-2 - immunology Lymphocyte Subsets - immunology Mammalia Molecular Sequence Data Molecular Weight Phylogeny Recombinant Proteins - biosynthesis Recombinant Proteins - genetics Recombinant Proteins - isolation & purification Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - biosynthesis RNA, Messenger - genetics Sequence Homology, Amino Acid T-cell growth factor Interleukin-15 Interleukin-2 T-cell growth factor Chickens Cytokine
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