Outpatient influenza antivirals in a distributed data network for influenza surveillance

Electronic data collected from routine health care can be used for public health surveillance. To examine the Sentinel System, a distributed data network of health plans, as a source for influenza surveillance, we compared trends in outpatient prescription dispensings of influenza antivirals in Sent...

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Bibliographic Details
Published in:	Influenza and other respiratory viruses Vol. 12; no. 6; pp. 804 - 807
Main Authors:	Cocoros, Noelle M., Panucci, Genna, Haug, Nicole, Maher, Carmen, Reichman, Marsha, Toh, Sengwee
Format:	Journal Article
Language:	English
Published:	England John Wiley & Sons, Inc 01-11-2018 John Wiley and Sons Inc
Subjects:	Adolescent Adult Aged Aged, 80 and over Antiviral agents Antiviral Agents - therapeutic use Child Child, Preschool Comparative analysis Drug Utilization - statistics & numerical data Epidemiological Monitoring Female Health care Health insurance Health surveillance Humans Infant Infant, Newborn infectious disease surveillance Influenza Influenza, Human - drug therapy Influenza, Human - epidemiology Male medical claims Middle Aged Oseltamivir Oseltamivir - therapeutic use Outpatients Pharmacy Powder Prescriptions - statistics & numerical data Public health Respiratory diseases Sentinel system Short Trends Viruses Young Adult Zanamivir Zanamivir - therapeutic use United States > US influenza infectious disease surveillance medical claims
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Summary:	Electronic data collected from routine health care can be used for public health surveillance. To examine the Sentinel System, a distributed data network of health plans, as a source for influenza surveillance, we compared trends in outpatient prescription dispensings of influenza antivirals in Sentinel to trends in CDC's ILINet and NREVSS systems over five seasons. There were 2 102 885 dispensed prescriptions of oseltamivir capsules, 494 188 of oseltamivir powder, and 7955 of zanamivir. Across all seasons, the magnitude and timing of peaks in drug utilization were highly comparable to those in ILINet and NREVSS. Oseltamivir capsules and powder were well correlated with ILINet and NREVSS. This lays the foundation for further exploration of Sentinel's utility for influenza surveillance.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Marsha Reichman and Carmen Maher were FDA employees at the time the work was performed.
ISSN:	1750-2640 1750-2659
DOI:	10.1111/irv.12598