Obesity phenotype and intra-abdominal fat responses to regular aerobic exercise

• Published in: Diabetes research and clinical practice Vol. 84; no. 3; pp. 230 - 238
• Main Authors: Sasai, Hiroyuki, Katayama, Yasutomi, Nakata, Yoshio, Ohkubo, Hiroyuki, Tanaka, Kiyoji
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier Ireland Ltd 01-06-2009
• Subjects: Abdominal Fat - anatomy & histology; Abdominal Fat - diagnostic imaging; Adult; Aerobiosis; Aged; Dyslipidemias - drug therapy; Dyslipidemias - epidemiology; Endocrinology & Metabolism; Exercise; Humans; Hypertension - drug therapy; Hypertension - epidemiology; Hypoglycemic Agents - therapeutic use; Hypolipidemic Agents - therapeutic use; Intra-abdominal fat; Middle Aged; Obesity - complications; Obesity - genetics; Obesity phenotype; Oxygen Consumption; Phenotype; Regular exercise; Tomography, X-Ray Computed; Weight Loss - physiology; Regular exercise; Intra-abdominal fat; Obesity phenotype
• ISSN: 0168-8227; 1872-8227
• DOI: 10.1016/j.diabres.2009.03.011

Abstract Aim To examine the effects of obesity phenotype on abdominal fat responses to regular aerobic exercise. Method Fifty-seven obese men aged 34–70 years were divided into two groups based on baseline intra-abdominal fat (IF) area measured by computerized tomography: moderate (<200 cm2 ) IF (MIF; n = 33, age: 52.9 ± 10.6 [SD] yr, body mass index [BMI]: 29.2 ± 3.1 kg/m2 ) or high (≥200 cm2 ) IF (HIF; n = 24, age: 53.5 ± 9.5 yr, BMI: 30.3 ± 3.1 kg/m2 ). The 12-week exercise program consisted primarily of aerobic exercise and met 3 days per week for 90 min per session. Weight, BMI, body composition (by dual-energy X-ray absorptiometry), IF and subcutaneous fat (SF) areas were measured before and after the program. Results Regular aerobic exercise reduced weight by 2.3 ± 2.2 kg in MIF and 3.2 ± 3.0 kg in HIF. HIF reduced significantly more IF area than MIF (15.1 ± 26.0 cm2 in MIF and 43.3 ± 41.9 cm2 in HIF), and the difference remained significant after adjusting for baseline fat mass, weight change and total energy intake during the 12-week aerobic exercise. Conclusion Exercise-induced IF reduction may be remarkably influenced by obesity phenotype.