Tensile Forces and Shape Entropy Explain Observed Crista Structure in Mitochondria

We present a model from which the observed morphology of the inner mitochondrial membrane can be inferred as minimizing the system's free energy. In addition to the usual energetic terms for bending, surface area, and pressure difference, our free energy includes terms for tension that we hypot...

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Bibliographic Details
Published in:	Biophysical journal Vol. 99; no. 10; pp. 3244 - 3254
Main Authors:	Ghochani, M., Nulton, J.D., Salamon, P., Frey, T.G., Rabinovitch, A., Baljon, A.R.C.
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 17-11-2010 Biophysical Society The Biophysical Society
Subjects:	Animals Cells Entropy Fibroblasts Free energy HeLa Cells Humans Lamellar structure Mathematical models Membrane Membranes Mice Mitochondria Mitochondria - metabolism Mitochondria - ultrastructure Mitochondrial Membranes - metabolism Mitochondrial Membranes - ultrastructure Models, Biological Molecular structure Organelle Shape Phases Proteins Rodents Tensile Strength - physiology
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