Biosynthesis of lasalocid A. Metabolic interrelationships of carboxylic acid precursors and polyether antibiotics

The metabolic interrelationships of isobutyrate, n-butyrate, and propionate in Streptomyces lasaliensis are established to show how these acids are used as precursors for the biosynthesis of the polyether antibiotic, lasalocid A.

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Bibliographic Details
Published in:	Journal of antibiotics Vol. 39; no. 8; p. 1135
Main Authors:	Sherman, M M, Yue, S, Hutchinson, C R
Format:	Journal Article
Language:	English
Published:	Japan 1986
Subjects:	Anti-Bacterial Agents - biosynthesis Butyrates - metabolism Butyric Acid Isobutyrates Lasalocid - biosynthesis Oxidation-Reduction Propionates - metabolism Streptomyces - metabolism
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Summary:	The metabolic interrelationships of isobutyrate, n-butyrate, and propionate in Streptomyces lasaliensis are established to show how these acids are used as precursors for the biosynthesis of the polyether antibiotic, lasalocid A.
ISSN:	0021-8820
DOI:	10.7164/antibiotics.39.1135