Human Dendritic Cells: Their Heterogeneity and Clinical Application Potential in Cancer Immunotherapy

Dendritic cells (DC) are professional antigen presenting cells, uniquely able to induce naïve T cell activation and effector differentiation. They are, likewise, involved in the induction and maintenance of immune tolerance in homeostatic conditions. Their phenotypic and functional heterogeneity poi...

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Bibliographic Details
Published in:	Frontiers in immunology Vol. 9; p. 3176
Main Authors:	Patente, Thiago A, Pinho, Mariana P, Oliveira, Aline A, Evangelista, Gabriela C M, Bergami-Santos, Patrícia C, Barbuto, José A M
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 21-01-2019
Subjects:	Animals Biomarkers cancer combination therapies Cancer Vaccines Cell Differentiation Combined Modality Therapy Dendritic Cells - cytology Dendritic Cells - immunology Dendritic Cells - metabolism human dendritic cells Humans Immune System - immunology Immune System - metabolism Immune System Phenomena Immunology Immunotherapy mo-DC monocyte-derived dendritic cells Neoplasms - immunology Neoplasms - pathology Neoplasms - therapy Phenotype Treatment Outcome Tumor Microenvironment - immunology cancer combination therapies mo-DC cancer vaccines monocyte-derived dendritic cells human dendritic cells DC
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