Liver Transplantation for Cholangiocarcinoma and Mixed Hepatocellular Cholangiocarcinoma: Working Group Report From the ILTS Transplant Oncology Consensus Conference

Liver transplantation for cholangiocarcinoma has been an absolute contraindication worldwide due to poor results. However, in recent years and thanks to improvements of patient management and treatments of this cancer, this indication has been revisited. This consensus paper, approved by the Interna...

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Published in:Transplantation Vol. 104; no. 6; pp. 1125 - 1130
Main Authors: Sapisochin, Gonzalo, Javle, Milind, Lerut, Jan, Ohtsuka, Masayuki, Ghobrial, Mark, Hibi, Taizo, Kwan, Nancy Man, Heimbach, Julie
Format: Journal Article
Language:English
Published: United States Wolters Kluwer Health, Inc. All rights reserved 01-06-2020
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Abstract Liver transplantation for cholangiocarcinoma has been an absolute contraindication worldwide due to poor results. However, in recent years and thanks to improvements of patient management and treatments of this cancer, this indication has been revisited. This consensus paper, approved by the International Liver Transplant Society, aims to provide a collection of expert opinions, consensus, and best practices surrounding liver transplantation for cholangiocarcinoma.
AbstractList Liver transplantation for cholangiocarcinoma has been an absolute contraindication worldwide due to poor results. However, in recent years and thanks to improvements of patient management and treatments of this cancer, this indication has been revisited. This consensus paper, approved by the International Liver Transplant Society, aims to provide a collection of expert opinions, consensus, and best practices surrounding liver transplantation for cholangiocarcinoma.
Author Lerut, Jan
Ghobrial, Mark
Sapisochin, Gonzalo
Kwan, Nancy Man
Ohtsuka, Masayuki
Javle, Milind
Heimbach, Julie
Hibi, Taizo
AuthorAffiliation Department of Pediatric Surgery and Transplantation, Kumamoto University Graduate School of Medical Sciences, Kumamoto, Japan
Institut de Recherche Expérimentale et Clinique (IREC), Université catholique de Louvain (UCL), Brussels, Belgium
J C Walter Jr Transplant Center, Sherrie and Alan Conover Center for Liver Disease and Transplantation, Weill Cornell Medical College, Houston Methodist Hospital and Research Institute, Houston, TX
Department of General Surgery, Chiba University Graduate School of Medicine, Chiba, Japan
Department of Surgery, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China
Division of Transplant Surgery, Mayo Clinic College of Medicine, Rochester, NY
MD Anderson Cancer Center, GI Medical Oncology, Houston, TX
Multi-Organ Transplant Program, Division of General Surgery, Toronto General Hospital, University Health Network, University of Toronto, Toronto, Canada
AuthorAffiliation_xml – name: Division of Transplant Surgery, Mayo Clinic College of Medicine, Rochester, NY
– name: MD Anderson Cancer Center, GI Medical Oncology, Houston, TX
– name: J C Walter Jr Transplant Center, Sherrie and Alan Conover Center for Liver Disease and Transplantation, Weill Cornell Medical College, Houston Methodist Hospital and Research Institute, Houston, TX
– name: Multi-Organ Transplant Program, Division of General Surgery, Toronto General Hospital, University Health Network, University of Toronto, Toronto, Canada
– name: Department of Surgery, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China
– name: Institut de Recherche Expérimentale et Clinique (IREC), Université catholique de Louvain (UCL), Brussels, Belgium
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– name: Department of General Surgery, Chiba University Graduate School of Medicine, Chiba, Japan
Author_xml – sequence: 1
  givenname: Gonzalo
  surname: Sapisochin
  fullname: Sapisochin, Gonzalo
  organization: Multi-Organ Transplant Program, Division of General Surgery, Toronto General Hospital, University Health Network, University of Toronto, Toronto, Canada
– sequence: 2
  givenname: Milind
  surname: Javle
  fullname: Javle, Milind
  organization: MD Anderson Cancer Center, GI Medical Oncology, Houston, TX
– sequence: 3
  givenname: Jan
  surname: Lerut
  fullname: Lerut, Jan
  organization: Institut de Recherche Expérimentale et Clinique (IREC), Université catholique de Louvain (UCL), Brussels, Belgium
– sequence: 4
  givenname: Masayuki
  surname: Ohtsuka
  fullname: Ohtsuka, Masayuki
  organization: Department of General Surgery, Chiba University Graduate School of Medicine, Chiba, Japan
– sequence: 5
  givenname: Mark
  surname: Ghobrial
  fullname: Ghobrial, Mark
  organization: J C Walter Jr Transplant Center, Sherrie and Alan Conover Center for Liver Disease and Transplantation, Weill Cornell Medical College, Houston Methodist Hospital and Research Institute, Houston, TX
– sequence: 6
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  surname: Hibi
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  organization: Department of Pediatric Surgery and Transplantation, Kumamoto University Graduate School of Medical Sciences, Kumamoto, Japan
– sequence: 7
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  surname: Heimbach
  fullname: Heimbach, Julie
  organization: Division of Transplant Surgery, Mayo Clinic College of Medicine, Rochester, NY
BackLink https://www.ncbi.nlm.nih.gov/pubmed/32217937$$D View this record in MEDLINE/PubMed
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Snippet Liver transplantation for cholangiocarcinoma has been an absolute contraindication worldwide due to poor results. However, in recent years and thanks to...
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StartPage 1125
SubjectTerms Bile Duct Neoplasms - mortality
Bile Duct Neoplasms - therapy
Chemoradiotherapy, Adjuvant - methods
Chemoradiotherapy, Adjuvant - standards
Cholangiocarcinoma - mortality
Cholangiocarcinoma - therapy
Consensus
Humans
Liver Transplantation - standards
Medical Oncology - standards
Neoadjuvant Therapy - methods
Neoadjuvant Therapy - standards
Practice Guidelines as Topic
Preoperative Care - methods
Preoperative Care - standards
Survival Rate
Treatment Outcome
Title Liver Transplantation for Cholangiocarcinoma and Mixed Hepatocellular Cholangiocarcinoma: Working Group Report From the ILTS Transplant Oncology Consensus Conference
URI http://ovidsp.ovid.com/ovidweb.cgi?T=JS&NEWS=n&CSC=Y&PAGE=fulltext&D=ovft&AN=00007890-202006000-00008
https://www.ncbi.nlm.nih.gov/pubmed/32217937
https://search.proquest.com/docview/2384203642
Volume 104
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