HIV-1 capsids bind and exploit the kinesin-1 adaptor FEZ1 for inward movement to the nucleus

Intracellular transport of cargos, including many viruses, involves directed movement on microtubules mediated by motor proteins. Although a number of viruses bind motors of opposing directionality, how they associate with and control these motors to accomplish directed movement remains poorly under...

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Bibliographic Details
Published in:	Nature communications Vol. 6; no. 1; p. 6660
Main Authors:	Malikov, Viacheslav, da Silva, Eveline Santos, Jovasevic, Vladimir, Bennett, Geoffrey, de Souza Aranha Vieira, Daniel A., Schulte, Bianca, Diaz-Griffero, Felipe, Walsh, Derek, Naghavi, Mojgan H.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 30-03-2015 Nature Publishing Group
Subjects:	13 14 38 42 631/326/596/2148 631/80/128/1653 631/80/128/2343 692/699/255/1901 82 96 Adaptor Proteins, Signal Transducing - metabolism Biological Transport Capsid - metabolism Cell Line Cell Nucleus - metabolism Dyneins - metabolism Fibroblasts HEK293 Cells HIV-1 - metabolism Humanities and Social Sciences Humans Kinesin - metabolism Microglia Microtubules - metabolism Monocytes multidisciplinary Nerve Tissue Proteins - metabolism RNA Interference Science Science (multidisciplinary) T-Lymphocytes
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