Measuring estradiol levels after human chorionic gonadotropin administration for in vitro fertilization is not clinically useful

• Published in: Fertility and sterility Vol. 87; no. 2; pp. 448 - 450
• Main Authors: Chiasson, Melissa D., M.D, Bates, G. Wright, M.D, Robinson, Randal D., M.D, Arthur, Nancy J., R.N, Propst, Anthony M., M.D
• Format: Journal Article Conference Proceeding
• Language: English
• Published: New York, NY Elsevier Inc 01-02-2007; Elsevier Science
• Subjects: Adult; Biological and medical sciences; Biomarkers - blood; Chorionic Gonadotropin - administration & dosage; Estradiol - blood; Female; Fertilization in Vitro; Gynecology. Andrology. Obstetrics; Humans; Infertility, Female - blood; Infertility, Female - diagnosis; Infertility, Female - therapy; Internal Medicine; Medical sciences; Obstetrics and Gynecology; Ovulation Induction - methods; Pregnancy; Pregnancy Rate; Prognosis; Reproducibility of Results; Retrospective Studies; Sensitivity and Specificity; In vitro fertilization embryo transfer; Human; Protein hormone; Fertility; Estrogen; Assisted procreation; Chorionic gonadotrophin; Sex steroid hormone; Estradiol; Ovarian hormone
• ISSN: 0015-0282; 1556-5653
• DOI: 10.1016/j.fertnstert.2006.06.024

A retrospective analysis of 844 IVF-ET cycles demonstrated that changes in E2 levels after administration of hCG do not influence fertilization, implantation, pregnancy, or live-birth rates. In vitro fertilization cycles with a declining E2 level have comparable success to those with no change or increasing E2 levels and should proceed to oocyte retrieval.