Transcriptional control of innate lymphocyte fate decisions

Highlights ► Differential roles of T-bet and Eomes for NK cell development. ► Lineage specification of type 2 ILC. ► The aryl hydrocarbon receptor controls the pool size of RORγt+ ILC. ► Lineage plasticity of RORγt+ ILC.

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Bibliographic Details
Published in:	Current opinion in immunology Vol. 24; no. 3; pp. 290 - 296
Main Authors:	Klose, Christoph SN, Hoyler, Thomas, Kiss, Elina A, Tanriver, Yakup, Diefenbach, Andreas
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01-06-2012
Subjects:	Adaptations Allergy and Immunology Animals Cell fate Cell Lineage Evolution Humans Immune response Immune system Immunity, Innate Killer Cells, Natural - immunology Lymphocytes - cytology Lymphocytes - immunology Lymphocytes T Lymphoid cells Natural killer cells Nuclear Receptor Subfamily 1, Group F, Member 3 - immunology Plastics Reviews Transcription Transcription, Genetic
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Summary:	Highlights ► Differential roles of T-bet and Eomes for NK cell development. ► Lineage specification of type 2 ILC. ► The aryl hydrocarbon receptor controls the pool size of RORγt+ ILC. ► Lineage plasticity of RORγt+ ILC.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 ObjectType-Feature-1
ISSN:	0952-7915 1879-0372
DOI:	10.1016/j.coi.2012.04.004