Anticancer therapy targeting the apoptotic pathway

Apoptosis, or programmed cell death, has an essential role in controlling cell number in many developmental and physiological settings and in chemotherapy-induced tumour-cell killing. It is a genetically regulated biological process, guided by the ratio of proapoptotic and antiapoptotic proteins. Re...

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Bibliographic Details

Published in:	The lancet oncology Vol. 4; no. 12; p. 721
Main Authors:	Hu, Wei, Kavanagh, John J
Format:	Journal Article
Language:	English
Published:	England 01-12-2003
Subjects:	Antineoplastic Agents - pharmacology Antineoplastic Agents - therapeutic use Apoptosis - drug effects Clinical Trials as Topic Drug Delivery Systems Humans Mitochondria - metabolism Models, Biological Tumor Necrosis Factor-alpha - genetics
Online Access:	Get more information
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