ALLHAT: a saga of missed opportunities
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| Published in: | Journal of human hypertension Vol. 17; no. 6; pp. 373 - 377 |
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| Format: | Journal Article |
| Language: | English |
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England
Nature Publishing Group
01-06-2003
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| Audience | Academic |
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| Author | McInnes, G T |
| Author_xml | – sequence: 1 givenname: G T surname: McInnes fullname: McInnes, G T email: kc3y@clinmed.gla.ac.uk organization: Division of Cardiovascular and Medical Sciences, University of Glasgow, Western Infirmary, Glasgow G11 6NT, UK. kc3y@clinmed.gla.ac.uk |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/12764398$$D View this record in MEDLINE/PubMed |
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| CitedBy_id | crossref_primary_10_1016_j_ijcard_2004_07_005 crossref_primary_10_1007_BF02850338 crossref_primary_10_1517_14728214_11_1_49 crossref_primary_10_1080_08037050310031819 crossref_primary_10_1038_sj_jhh_1001683 |
| Cites_doi | 10.7326/0003-4819-137-5_Part_1-200209030-00006 10.1016/0140-6736(90)90944-Z 10.1016/S0140-6736(01)06411-X 10.1016/S0033-0620(85)80003-7 10.1016/S0140-6736(00)02526-5 10.1001/archinte.1989.00390120021005 10.1111/j.1524-6175.2002.02045.x 10.1161/01.CIR.92.5.1326 10.1016/S0140-6736(98)05012-0 10.1136/bmj.300.6737.1465-a 10.1056/NEJM199903043400902 10.1093/oxfordjournals.bmb.a072892 10.1056/NEJM199803053381009 10.1097/00004872-199204000-00002 10.1001/jama.1997.03540330061036 10.1016/S0140-6736(00)02527-7 10.1001/jama.283.15.1967 10.1001/archinte.1997.00440420033005 10.1016/S0140-6736(99)10327-1 10.1016/0002-8703(87)90606-5 10.1016/S0140-6736(98)04311-6 10.1001/archinte.1990.00040031707020 10.1016/S0140-6736(00)02327-8 10.1056/NEJM200105033441802 10.1016/S1071-9164(99)90001-5 10.1001/jama.288.23.2981 10.1016/S0889-8529(05)70237-1 10.1016/S0140-6736(00)03306-7 10.1038/sj.jhh.1000917 10.1001/archinte.160.6.825 |
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| Copyright | COPYRIGHT 2003 Nature Publishing Group Copyright Nature Publishing Group Jun 2003 Nature Publishing Group 2003. |
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| DOI | 10.1038/sj.jhh.1001564 |
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| References | 1997; 157 Furberg, CD, Psaty, BM, Meyer, JV 1995; 92 Collins, R, MacMahon, S 1994; 50 2000; 355 Poulter, N, Sever, P, Thom, S 1990; 300 Pahor, M 2000; 352 Rahman, M, Douglas, JG, Wright, JT 1997; 26 Hansson, L 1999; 353 Hansson, L 1999; 354 Yusuf, S 1985; 27 Cushman, WC 2002; 4 Collins, R 1990; 335 Davis, BR 2002; 137 Robertson, JIS 1987; 114 Saunders, E 1990; 150 Brown, MJ 2000; 356 Weinberger, MH 1988; 11 2002; 288 Exner, DV, Dries, DL, Domanski, MJ, Cohn, JN 2001; 344 Ramsay, L 1999; 13 2000; 283 Hansson, L 1998; 351 Cushman, WC 2000; 160 Psaty, BM 1997; 277 Hansson, L 2000; 356 Tuomilehto, J 1999; 340 Cutler, JA 1998; 338 Staessen, JA, Wang, JG, Thijs, L 2001; 358 Carson, P, Ziesche, S, Johnson, G, Cohn, JN 1999; 5 Kaplan, NM 1989; 149 McInnes, GT, Yeo, WW, Ramsay, LE, Moser, M 1992; 10 Poole-Wilson, PA 1983; 59 S Yusuf (BF1001564_CR7) 1985; 27 M Pahor (BF1001564_CR15) 2000; 352 MH Weinberger (BF1001564_CR6) 1988; 11 WC Cushman (BF1001564_CR25) 2002; 4 DV Exner (BF1001564_CR27) 2001; 344 L Hansson (BF1001564_CR13) 2000; 356 GT McInnes (BF1001564_CR32) 1992; 10 PA Poole-Wilson (BF1001564_CR3) 1983; 59 BM Psaty (BF1001564_CR9) 1997; 277 L Hansson (BF1001564_CR11) 1999; 353 BR Davis (BF1001564_CR31) 2002; 137 J Tuomilehto (BF1001564_CR19) 1999; 340 JIS Robertson (BF1001564_CR5) 1987; 114 R Collins (BF1001564_CR1) 1994; 50 The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group (BF1001564_CR16) 2002; 288 MJ Brown (BF1001564_CR12) 2000; 356 The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group (BF1001564_CR30) 2000; 283 E Saunders (BF1001564_CR24) 1990; 150 L Hansson (BF1001564_CR17) 1998; 351 P Carson (BF1001564_CR26) 1999; 5 JA Staessen (BF1001564_CR18) 2001; 358 Blood Pressure Lowering Treatment Trialists' Collaboration (BF1001564_CR14) 2000; 355 R Collins (BF1001564_CR8) 1990; 335 JA Cutler (BF1001564_CR28) 1998; 338 L Ramsay (BF1001564_CR20) 1999; 13 L Hansson (BF1001564_CR10) 1999; 354 Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure (BF1001564_CR21) 1997; 157 CD Furberg (BF1001564_CR29) 1995; 92 NM Kaplan (BF1001564_CR2) 1989; 149 M Rahman (BF1001564_CR23) 1997; 26 N Poulter (BF1001564_CR4) 1990; 300 WC Cushman (BF1001564_CR22) 2000; 160 |
| References_xml | – volume: 300 start-page: 1465 year: 1990 article-title: Antihypertensive and adverse biochemical effects of bendrofluazide publication-title: BMJ contributor: fullname: Thom, S – volume: 27 start-page: 335 year: 1985 end-page: 371 article-title: Beta-blockade during and after myocardial infarction: an overview of the randomized trials publication-title: Prog Cardiovasc Dis contributor: fullname: Yusuf, S – volume: 10 start-page: 317 year: 1992 end-page: 335 article-title: Cardiotoxicity of diuretics: much speculation-little substance publication-title: J Hypertens contributor: fullname: Moser, M – volume: 137 start-page: 313 year: 2002 end-page: 320 article-title: Relationship of antihypertensive treatment regimens and change in blood pressure to risk for heart failure in hypertensive patients randomly assigned to doxazosin or chlorthalidone: further analyses from the Antihypertensive and Lipid-Lowering treatment to prevent Heart Attack Trial publication-title: Ann Intern Med contributor: fullname: Davis, BR – volume: 353 start-page: 611 year: 1999 end-page: 616 article-title: Effect of angiotensin-converting enzyme inhibition compared with conventional therapy on cardiovascular morbidity and mortality in hypertension: the Captopril Prevention Project (CAPPP) randomised trial publication-title: Lancet contributor: fullname: Hansson, L – volume: 160 start-page: 825 year: 2000 end-page: 831 article-title: Regional and racial difference in response to antihypertensive medication use in a randomised controlled trial of men with hypertension in the United States publication-title: Arch Intern Med contributor: fullname: Cushman, WC – volume: 277 start-page: 739 year: 1997 end-page: 745 article-title: Health outcomes associated with antihypertensive therapies used as first-line agents: a systematic review and meta-analysis publication-title: JAMA contributor: fullname: Psaty, BM – volume: 92 start-page: 1326 year: 1995 end-page: 1331 article-title: Nifedipine: dose-related increase in mortality in patients with coronary heart disease publication-title: Circulation contributor: fullname: Meyer, JV – volume: 59 start-page: 137 year: 1983 end-page: 139 article-title: Hypokalaemia induced by thiazide diuretics in the treatment of hypertension: a cause for concern, not nihilism publication-title: Postgrad Med J contributor: fullname: Poole-Wilson, PA – volume: 11 start-page: II-16 year: 1988 end-page: II-20 article-title: Diuretics and their side-effects. Dilemma in the treatment of hypertension publication-title: Hypertension contributor: fullname: Weinberger, MH – volume: 288 start-page: 2981 year: 2002 end-page: 2997 article-title: Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker diuretic. The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) publication-title: JAMA – volume: 13 start-page: 569 year: 1999 end-page: 592 article-title: Guidelines for management of hypertension: report of the third working party of the British Hypertension Society publication-title: J Hum Hypertens contributor: fullname: Ramsay, L – volume: 344 start-page: 1351 year: 2001 end-page: 1357 article-title: Lesser response to angiotensin-converting-enzyme inhibitor therapy in black as compared with white patients with left ventricular dysfunction publication-title: N Engl J Med contributor: fullname: Cohn, JN – volume: 354 start-page: 1751 year: 1999 end-page: 1756 article-title: Randomised trial of old and new antihypertensive drugs in elderly patients: cardiovascular mortality and morbidity the Swedish Trial in Old Patients with Hypertension-2 Study publication-title: Lancet contributor: fullname: Hansson, L – volume: 157 start-page: 2413 year: 1997 end-page: 2461 article-title: The sixth report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure publication-title: Arch Intern Med – volume: 4 start-page: 393 year: 2002 end-page: 405 article-title: Success and predictors of blood pressure control in diverse North American settings: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) publication-title: J Clin Hypertens contributor: fullname: Cushman, WC – volume: 5 start-page: 178 year: 1999 end-page: 187 article-title: Racial differences in response to therapy for heart failure: analysis of the vasodilator-heart failure trials: Vasodilator-Heart Failure Trial Study Group publication-title: J Card Fail contributor: fullname: Cohn, JN – volume: 335 start-page: 827 year: 1990 end-page: 838 article-title: Blood pressure, stroke and coronary heart disease. Part 2, short-term reductions in blood pressure: overview of randomised drug trials in their epidemiological context publication-title: Lancet contributor: fullname: Collins, R – volume: 340 start-page: 677 year: 1999 end-page: 684 article-title: Effects of calcium channel blockers in older patients with diabetes and systolic hypertension publication-title: N Engl J Med contributor: fullname: Tuomilehto, J – volume: 351 start-page: 1755 year: 1998 end-page: 1762 article-title: Effects of intensive blood pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial publication-title: Lancet contributor: fullname: Hansson, L – volume: 50 start-page: 272 year: 1994 end-page: 298 article-title: Blood pressure, antihypertensive drug treatment and the risks of stroke and of coronary heart disease publication-title: Br Med Bull contributor: fullname: MacMahon, S – volume: 355 start-page: 1955 year: 2000 end-page: 1964 article-title: Effects of ACE inhibitors, calcium antagonists, and other blood-pressure-lowering drugs: results of prospectively designed overviews of randomised trials publication-title: Lancet – volume: 352 start-page: 1949 year: 2000 end-page: 1954 article-title: Health outcomes associated with calcium antagonists compared with the first-line antihypertensive therapies: a meta-analysis of randomised controlled trials publication-title: Lancet contributor: fullname: Pahor, M – volume: 358 start-page: 1305 year: 2001 end-page: 1315 article-title: Cardiovascular protection and blood pressure reduction: a meta-analysis publication-title: Lancet contributor: fullname: Thijs, L – volume: 26 start-page: 125 year: 1997 end-page: 144 article-title: Pathophysiology and treatment implications of hypertension in the African-American population publication-title: Endocrinol Metab Clin North Am contributor: fullname: Wright, JT – volume: 149 start-page: 2649 year: 1989 article-title: How bad are diuretic-induced hypok-alemia and hypercholesterolemia? publication-title: Arch Intern Med contributor: fullname: Kaplan, NM – volume: 283 start-page: 1967 year: 2000 end-page: 1975 article-title: Major cardiovascular events on hypertensive patients randomized to doxazosin vs chlorthalidone. The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) publication-title: JAMA – volume: 356 start-page: 366 year: 2000 end-page: 377 article-title: Morbidity and mortality in patients randomised to double-blind treatment with a long-acting calcium channel blocker or diuretic in the International Nifedipine GITS Study: intervention as a Goal in Hypertension Treatment (INSIGHT) publication-title: Lancet contributor: fullname: Brown, MJ – volume: 356 start-page: 359 year: 2000 end-page: 365 article-title: Randomised trial of effects of calcium antagonists compared with diuretics and -blockers on cardio-vascular morbidity and mortality in hypertension: the Nordic Diltiazem (NORDIL) Study publication-title: Lancet contributor: fullname: Hansson, L – volume: 114 start-page: S1051 year: 1987 end-page: S1054 article-title: Hypertension and coronary risk: possible adverse effects of antihypertensive drugs publication-title: Am Heart J contributor: fullname: Robertson, JIS – volume: 150 start-page: 1707 year: 1990 end-page: 1713 article-title: A comparison of the efficacy and safety of a beta-blocker, a calcium channel blocker, and a converting enzyme inhibitor in hypertensive blacks publication-title: Arch Intern Med contributor: fullname: Saunders, E – volume: 338 start-page: 679 year: 1998 end-page: 681 article-title: Calcium channel blockers for hypertension-uncertainty continues publication-title: N Engl J Med contributor: fullname: Cutler, JA – volume: 137 start-page: 313 year: 2002 ident: BF1001564_CR31 publication-title: Ann Intern Med doi: 10.7326/0003-4819-137-5_Part_1-200209030-00006 contributor: fullname: BR Davis – volume: 335 start-page: 827 year: 1990 ident: BF1001564_CR8 publication-title: Lancet doi: 10.1016/0140-6736(90)90944-Z contributor: fullname: R Collins – volume: 358 start-page: 1305 year: 2001 ident: BF1001564_CR18 publication-title: Lancet doi: 10.1016/S0140-6736(01)06411-X contributor: fullname: JA Staessen – volume: 27 start-page: 335 year: 1985 ident: BF1001564_CR7 publication-title: Prog Cardiovasc Dis doi: 10.1016/S0033-0620(85)80003-7 contributor: fullname: S Yusuf – volume: 356 start-page: 359 year: 2000 ident: BF1001564_CR13 publication-title: Lancet doi: 10.1016/S0140-6736(00)02526-5 contributor: fullname: L Hansson – volume: 149 start-page: 2649 year: 1989 ident: BF1001564_CR2 publication-title: Arch Intern Med doi: 10.1001/archinte.1989.00390120021005 contributor: fullname: NM Kaplan – volume: 4 start-page: 393 year: 2002 ident: BF1001564_CR25 publication-title: J Clin Hypertens doi: 10.1111/j.1524-6175.2002.02045.x contributor: fullname: WC Cushman – volume: 92 start-page: 1326 year: 1995 ident: BF1001564_CR29 publication-title: Circulation doi: 10.1161/01.CIR.92.5.1326 contributor: fullname: CD Furberg – volume: 353 start-page: 611 year: 1999 ident: BF1001564_CR11 publication-title: Lancet doi: 10.1016/S0140-6736(98)05012-0 contributor: fullname: L Hansson – volume: 300 start-page: 1465 year: 1990 ident: BF1001564_CR4 publication-title: BMJ doi: 10.1136/bmj.300.6737.1465-a contributor: fullname: N Poulter – volume: 340 start-page: 677 year: 1999 ident: BF1001564_CR19 publication-title: N Engl J Med doi: 10.1056/NEJM199903043400902 contributor: fullname: J Tuomilehto – volume: 50 start-page: 272 year: 1994 ident: BF1001564_CR1 publication-title: Br Med Bull doi: 10.1093/oxfordjournals.bmb.a072892 contributor: fullname: R Collins – volume: 338 start-page: 679 year: 1998 ident: BF1001564_CR28 publication-title: N Engl J Med doi: 10.1056/NEJM199803053381009 contributor: fullname: JA Cutler – volume: 10 start-page: 317 year: 1992 ident: BF1001564_CR32 publication-title: J Hypertens doi: 10.1097/00004872-199204000-00002 contributor: fullname: GT McInnes – volume: 277 start-page: 739 year: 1997 ident: BF1001564_CR9 publication-title: JAMA doi: 10.1001/jama.1997.03540330061036 contributor: fullname: BM Psaty – volume: 356 start-page: 366 year: 2000 ident: BF1001564_CR12 publication-title: Lancet doi: 10.1016/S0140-6736(00)02527-7 contributor: fullname: MJ Brown – volume: 283 start-page: 1967 year: 2000 ident: BF1001564_CR30 publication-title: JAMA doi: 10.1001/jama.283.15.1967 contributor: fullname: The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group – volume: 157 start-page: 2413 year: 1997 ident: BF1001564_CR21 publication-title: Arch Intern Med doi: 10.1001/archinte.1997.00440420033005 contributor: fullname: Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure – volume: 354 start-page: 1751 year: 1999 ident: BF1001564_CR10 publication-title: Lancet doi: 10.1016/S0140-6736(99)10327-1 contributor: fullname: L Hansson – volume: 59 start-page: 137 issue: Suppl 3 year: 1983 ident: BF1001564_CR3 publication-title: Postgrad Med J contributor: fullname: PA Poole-Wilson – volume: 114 start-page: S1051 year: 1987 ident: BF1001564_CR5 publication-title: Am Heart J doi: 10.1016/0002-8703(87)90606-5 contributor: fullname: JIS Robertson – volume: 351 start-page: 1755 year: 1998 ident: BF1001564_CR17 publication-title: Lancet doi: 10.1016/S0140-6736(98)04311-6 contributor: fullname: L Hansson – volume: 150 start-page: 1707 year: 1990 ident: BF1001564_CR24 publication-title: Arch Intern Med doi: 10.1001/archinte.1990.00040031707020 contributor: fullname: E Saunders – volume: 355 start-page: 1955 year: 2000 ident: BF1001564_CR14 publication-title: Lancet doi: 10.1016/S0140-6736(00)02327-8 contributor: fullname: Blood Pressure Lowering Treatment Trialists' Collaboration – volume: 344 start-page: 1351 year: 2001 ident: BF1001564_CR27 publication-title: N Engl J Med doi: 10.1056/NEJM200105033441802 contributor: fullname: DV Exner – volume: 5 start-page: 178 year: 1999 ident: BF1001564_CR26 publication-title: J Card Fail doi: 10.1016/S1071-9164(99)90001-5 contributor: fullname: P Carson – volume: 288 start-page: 2981 year: 2002 ident: BF1001564_CR16 publication-title: JAMA doi: 10.1001/jama.288.23.2981 contributor: fullname: The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group – volume: 11 start-page: II-16 issue: Suppl II year: 1988 ident: BF1001564_CR6 publication-title: Hypertension contributor: fullname: MH Weinberger – volume: 26 start-page: 125 year: 1997 ident: BF1001564_CR23 publication-title: Endocrinol Metab Clin North Am doi: 10.1016/S0889-8529(05)70237-1 contributor: fullname: M Rahman – volume: 352 start-page: 1949 year: 2000 ident: BF1001564_CR15 publication-title: Lancet doi: 10.1016/S0140-6736(00)03306-7 contributor: fullname: M Pahor – volume: 13 start-page: 569 year: 1999 ident: BF1001564_CR20 publication-title: J Hum Hypertens doi: 10.1038/sj.jhh.1000917 contributor: fullname: L Ramsay – volume: 160 start-page: 825 year: 2000 ident: BF1001564_CR22 publication-title: Arch Intern Med doi: 10.1001/archinte.160.6.825 contributor: fullname: WC Cushman |
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| SubjectTerms | Antihypertensive Agents - therapeutic use Cardiovascular diseases Care and treatment Clinical Protocols Clinical Trials as Topic Dosage and administration Humans Hyperlipidemias - complications Hyperlipidemias - drug therapy Hypertension Hypertension - complications Hypertension - drug therapy Hypolipidemic Agents - therapeutic use Myocardial Infarction - etiology Myocardial Infarction - prevention & control Outcome Assessment (Health Care) Patient outcomes Predictive Value of Tests Prevention Thiazides |
| Title | ALLHAT: a saga of missed opportunities |
| URI | http://dx.doi.org/10.1038/sj.jhh.1001564 https://www.ncbi.nlm.nih.gov/pubmed/12764398 https://www.proquest.com/docview/219961174 https://www.proquest.com/docview/2640662920 https://search.proquest.com/docview/73275630 |
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