The transmembrane adaptor protein NTAL signals to mast cell cytoskeleton via the small GTPase Rho

The transmembrane adaptor protein NTAL (non‐T‐cell activation linker) participates in signalosome assembly in hematopoietic cells, but its exact role in cell physiology remains enigmatic. We report here that BM‐derived mast cells from NTAL‐deficient mice, responding to Ag alone or in combination wit...

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Bibliographic Details
Published in:	European journal of immunology Vol. 40; no. 11; pp. 3235 - 3245
Main Authors:	Tůmová, Magda, Koffer, Anna, Šimíček, Michal, Dráberová, Lubica, Dráber, Petr
Format:	Journal Article
Language:	English
Published:	Weinheim WILEY‐VCH Verlag 01-11-2010 Wiley Subscription Services, Inc
Subjects:	Actins - genetics Actins - immunology Actins - metabolism Animals Antigens - immunology Bone Marrow Cells - cytology Bone Marrow Cells - immunology Bone Marrow Cells - metabolism Cell activation Cytoskeleton Cytoskeleton - genetics Cytoskeleton - immunology Cytoskeleton - metabolism Mast cells Mast Cells - cytology Mast Cells - immunology Mast Cells - metabolism Mice Mice, Knockout Proteins - genetics Proteins - immunology Proteins - metabolism rac GTP-Binding Proteins - genetics rac GTP-Binding Proteins - immunology rac GTP-Binding Proteins - metabolism rho GTP-Binding Proteins - genetics rho GTP-Binding Proteins - immunology rho GTP-Binding Proteins - metabolism Signal Transduction - genetics Signal Transduction - immunology
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