Visualizing the dynamic coupling of claudin strands to the actin cytoskeleton through ZO-1

The organization and integrity of epithelial tight junctions depend on interactions between claudins, ZO scaffolding proteins, and the cytoskeleton. However, although binding between claudins and ZO-1/2/3 and between ZO-1/2/3 and numerous cytoskeletal proteins has been demonstrated in vitro, fluores...

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Bibliographic Details
Published in:	Molecular biology of the cell Vol. 28; no. 4; pp. 524 - 534
Main Authors:	Van Itallie, Christina M, Tietgens, Amber Jean, Anderson, James M
Format:	Journal Article
Language:	English
Published:	United States The American Society for Cell Biology 15-02-2017
Series:	A Highlights from
Subjects:	Actin Cytoskeleton - metabolism Actins - metabolism Animals Cell Line Claudin-1 - metabolism Claudins - metabolism Cytoskeletal Proteins - metabolism Cytoskeleton - physiology HEK293 Cells Humans Membrane Proteins - metabolism Molecular Imaging - methods Occludin - metabolism Phosphoproteins - metabolism Rats Tight Junctions - metabolism Zonula Occludens-1 Protein - metabolism Zonula Occludens-1 Protein - physiology
Online Access:	Get full text
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