Thermally Targeted p50 Peptide Inhibits Proliferation and Induces Apoptosis of Breast Cancer Cell Lines

The application of rationally designed therapeutic peptides (TP) may improve outcomes in cancer treatment. These peptides hold the potential to directly target proliferative pathways and stimulate cell arrest or death pathways. Elastin‐like polypeptide (ELP) is an elastin derived biopolymer that und...

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Bibliographic Details
Published in:	Macromolecular bioscience Vol. 20; no. 10; pp. e2000170 - n/a
Main Authors:	Thomas, Emily, Dragojevic, Sonja, Price, Amira, Raucher, Drazen
Format:	Journal Article
Language:	English
Published:	Germany Wiley Subscription Services, Inc 01-10-2020
Subjects:	Apoptosis Biopolymers Breast cancer Cancer Cell death cell penetrating peptide Cell proliferation Cell survival drug delivery Elastin elastin‐like polypeptide Localization Macromolecules Metastases NF-κB protein p50 Peptides Phase transitions Polypeptides Solid tumors Tumor cell lines Tumors p50 drug delivery cell penetrating peptide elastin-like polypeptide
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