RTA1 Is Involved in Resistance to 7-Aminocholesterol and Secretion of Fungal Proteins in Cryptococcus neoformans

Cryptococcus neoformans (Cn) is a pathogenic yeast that is the leading cause of fungal meningitis in immunocompromised patients. Various Cn virulence factors, such as the enzyme laccase and its product melanin, phospholipase, and capsular polysaccharide have been identified. During a screen of knock...

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Bibliographic Details
Published in:	Pathogens (Basel) Vol. 11; no. 11; p. 1239
Main Authors:	Smith-Peavler, Emily S., Patel, Ronakkumar, Onumajuru, Adejumoke Mary, Bowring, Bethany G., Miller, Joyce L., Brunel, Jean Michel, Djordjevic, Julianne T., Prabu, Moses M., McClelland, Erin E.
Format:	Journal Article
Language:	English
Published:	Basel MDPI AG 26-10-2022 MDPI
Subjects:	Antiinfectives and antibacterials Antimicrobial agents Biosynthesis Capsular polysaccharides Cell membranes Cloning Cryptococcus neoformans E coli Enzymes extracellular vesicles Fungi Glucuronoxylomannan Human health and pathology Immunocompromised hosts Infectious diseases Laccase Life Sciences Lipids Melanin Meningitis Mutants Pathogens Polysaccharides Proteins Resistance factors RNA-mediated interference RTA1 secretion Sterols Transmission electron microscopy Urease Virulence Virulence factors Yeast Yeasts St Louis Missouri United States > US secretion extracellular vesicles Cryptococcus neoformans RTA1
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