Antioxidant effect of peony seed oil on aging mice

• Published in: Food science and biotechnology Vol. 26; no. 6; pp. 1703 - 1708
• Main Authors: Han, Xiao-Miao, Wu, Su-Xi, Wu, Mei-Fang, Yang, Xue-Feng
• Format: Journal Article
• Language: English
• Published: Singapore Springer Singapore 01-12-2017; Springer Nature B.V; 한국식품과학회
• Subjects: Aging; Amine oxidase (flavin-containing); Antioxidants; Brain; Chemistry; Chemistry and Materials Science; Copper; D-Galactose; Food Science; Galactose; Genotype & phenotype; Glutathione; Glutathione peroxidase; Liver; Malondialdehyde; Manganese; Mice; Nutrition; Oil; Peroxidase; Seeds; Superoxide dismutase; Vitamin E; Zinc; 식품과학; Aging; Peony seed oil; Superoxide dismutase; Anti-aging
• ISSN: 1226-7708; 2092-6456
• DOI: 10.1007/s10068-017-0225-9

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-galactose was injected into mice of ages 4–5 months, and peony seed oil was administered using an oral gavage to assess its possible anti-aging functions. The content of malondialdehyde (MDA) and the activities of monoamine oxidase (MAO), glutathione peroxidase (GSH-Px), and superoxide dismutase (SOD) in the brain and liver of these mice were determined using biochemical kits. The significance of the differences in the content of the components associated with aging and anti-aging among each group was analyzed statistically. The MDA content and activities of MAO in the brain and liver of mice in the peony seed oil group were significantly lower than those in the aging group. The activities of GSH-Px, Cu/Zn-SOD, and Mn-SOD in the brain and liver of mice in the peony seed oil group were very significantly higher than those in the aging group. Peony seed oil was determined to have an obvious anti-aging function.