Steroid-Responsive Large Vessel Vasculitis: Application of Whole-Brain 320-Detector Row Dynamic Volume CT Angiography and Perfusion

• Published in: American journal of neuroradiology : AJNR Vol. 30; no. 7; pp. 1409 - 1411
• Main Authors: Yahyavi-Firouz-Abadi, N, Wynn, B.L, Rybicki, F.J, Steigner, M.L, Hussain, A.Z, Mather, R, Hanson, E.H, Ansarinia, M, Orrison, W.W., Jr
• Format: Journal Article
• Language: English
• Published: Oak Brook, IL Am Soc Neuroradiology 01-08-2009; American Society of Neuroradiology
• Subjects: Adrenal Cortex Hormones - therapeutic use; Adult; Biological and medical sciences; Brain; Cerebral Angiography - methods; Cerebrovascular Disorders - diagnostic imaging; Cerebrovascular Disorders - drug therapy; Fundamental and applied biological sciences. Psychology; Humans; Imaging, Three-Dimensional - methods; Investigative techniques, diagnostic techniques (general aspects); Male; Medical sciences; Nervous system; Perfusion Imaging - methods; Personality. Affectivity; Psychology. Psychoanalysis. Psychiatry; Psychology. Psychophysiology; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Sexuality. Sexual behavior; Tomography, X-Ray Computed - methods; Vasculitis - diagnostic imaging; Vasculitis - drug therapy; Vascular disease; Steroid; Nervous system diseases; Detector; Vasculitis; Angiography; Radiodiagnosis; Central nervous system; Cardiovascular disease; Computerized axial tomography; Encephalon
• ISSN: 0195-6108; 1936-959X
• DOI: 10.3174/ajnr.A1532

A patient with suspected giant cell arteritis and prior negative findings on superficial temporal artery biopsy was evaluated with 320-detector row CT angiography (CTA) and whole-brain perfusion. Corticosteroid treatment was initiated on the basis of CT angiography findings of arteritis and a cortical perfusion deficit. The patient's symptoms and perfusion imaging findings resolved following therapy. Whole-brain CTA and imaging was helpful in the diagnosis and monitoring this patient with suspected vasculitis.