RanBP2/Nup358 Mediates Sumoylation of STAT1 and Antagonizes Interferon-α-Mediated Antiviral Innate Immunity

Type I interferon (IFN-I)-induced signaling plays a critical role in host antiviral innate immune responses. Despite this, the mechanisms that regulate this signaling pathway have yet to be fully elucidated. The nucleoporin Ran Binding Protein 2 (RanBP2) (also known as Nucleoporin 358 KDa, Nup358) h...

Full description

Saved in:

Bibliographic Details
Published in:	International journal of molecular sciences Vol. 25; no. 1; p. 299
Main Authors:	Li, Jiawei, Su, Lili, Jiang, Jing, Wang, Yifan E, Ling, Yingying, Qiu, Yi, Yu, Huahui, Huang, Yucong, Wu, Jiangmin, Jiang, Shan, Zhang, Tao, Palazzo, Alexander F, Shen, Qingtang
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 25-12-2023 MDPI
Subjects:	Antibodies Biological response modifiers CRISPR Cytokine storm Enzymes Health aspects Immune response Infection Infections innate immunity Interferon Kinases Localization Medical research Medicine, Experimental MicroRNAs Mutation Phosphorylation Porins Protein binding Proteins RanBP2 STAT1 sumoylation Transcription factors Tumor necrosis factor-TNF viral infection Viral infections China RanBP2 sumoylation viral infection innate immunity interferon STAT1
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!