Migration of BADGE (bisphenol A diglycidyl-ether) and BFDGE (bisphenol F diglycidyl-ether) in canned seafood

• Published in: Food and chemical toxicology Vol. 46; no. 5; pp. 1674 - 1680
• Main Authors: Cabado, Ana G., Aldea, Susana, Porro, Corina, Ojea, Gonzalo, Lago, Jorge, Sobrado, Cristina, Vieites, Juan M.
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ltd 01-05-2008; New York, NY Elsevier Science
• Subjects: Animals; BADGE; Benzhydryl Compounds; BFDGE; Biological and medical sciences; bisphenol A diglycidyl-ether; bisphenol F diglycidyl-ether; Bivalvia; canned fish; canned foods; Canned seafood; Carcinogens - analysis; Chromatography, High Pressure Liquid; Epoxy Compounds - analysis; Food Analysis; food composition; food contamination; Food Preservation; food processing; food safety; Gadus morhua; heat treatment; high performance liquid chromatography; Indicators and Reagents; kinetics; lipid content; Lipids - analysis; Marine; Medical sciences; Migration; packaging materials; packaging materials migration; Perciformes; phenols; Reproducibility of Results; Sardinops; Scomber; Seafood - analysis; seafoods; species differences; Sterilization; storage time; Temperature; Thunnus; Time Factors; Toxicology; Tuna; Canned seafood; BPA (bisphenol A); BADGE; BFDGE; Migration; Bisphenol A; Ether; Seafood; Cell migration; Food
• ISSN: 0278-6915; 1873-6351
• DOI: 10.1016/j.fct.2008.01.006

Migration of potentially toxic materials used for the lining of commercial can goods remains an important issue, especially with respect to certain types of processed foods. Seafood is one type where more information is needed with respect to other ingredients used for adding value to fishery products. Most cans are internally coated with starters of resins such as bisphenol A diglycidyl-ether (BADGE) and bisphenol F diglycidyl-ether (BFDGE), both considered as toxic compounds. Several seafood products, sardines, tuna fish, mackerel, mussels, cod and mackerel eggs, were manufactured in different conditions changing covering sauce, time and temperature of storage and heat-treated for sterilization in cans. Migration kinetics of BADGE and BFDGE from varnish into canned products were evaluated by HPLC in 70 samples after 6, 12 or 18months of storage.
Results showed that there is no migration of BADGE in tuna fish, sardines, mussels or cod. However, migration of BFDGE occurs in all species, in a storage time-dependent way and content of fat, although migration of these compounds is not affected by sterilization conditions. All samples analyzed presented values lower than 9mg BADGE/kg net product without exceeding European limits. However, concerning BFDGE migration, European legislation does not allow the use and/or the presence of BFDGE. Main migration takes place in mackerel reaching the highest values, 0.74mg BFDGE/kg and 0.34mg BADGE/kg net product, in red pepper sauce.