Maxadilan-simile expression in Nyssomyia neivai, a sandfly vector in an endemic region of Brazil, and its immunogenicity in patients with American tegumentary leishmaniasis

Maxadilan (Max) is a salivary component in the sandfly Lutzomyia longipalpis (Lutz & Neiva 1912), a vector of visceral leishmaniasis. Max has a powerful vasodilatory effect and is a candidate vaccine that has been tested in experimental leishmaniasis. Nyssomyia neivai (Pinto 1926) is a vector of...

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Bibliographic Details
Published in:	Memórias do Instituto Oswaldo Cruz Vol. 112; no. 2; pp. 116 - 122
Main Authors:	Aires, Juliana, Casanova, Claudio, Vernal, Sebastian, Nascimento, Margarida, Rodrigues, Sandra, Lerner, Ethan A, Roselino, Ana Maria
Format:	Journal Article
Language:	English
Published:	Brazil Instituto Oswaldo Cruz, Ministério da Saúde 01-02-2017 Fundação Oswaldo Cruz (FIOCRUZ)
Subjects:	Animals Antibodies - blood Antibodies - immunology Brazil Case-Control Studies Endemic Diseases Enzyme-Linked Immunosorbent Assay Female Humans Immunoblotting Insect Proteins - analysis Insect Proteins - immunology Insect Vectors - chemistry Insect Vectors - classification leishmaniasis Leishmaniasis, Cutaneous - blood Leishmaniasis, Cutaneous - immunology Male Maxadilan protein PARASITOLOGY Polymerase Chain Reaction Psychodidae Psychodidae - chemistry Psychodidae - classification Rabbits Sequence Analysis, DNA TROPICAL MEDICINE leishmaniasis Psychodidae Maxadilan protein
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