Abnormalities in Copper Status Associated with an Elevated Risk of Parkinson’s Phenotype Development
In the last 15 years, among the many reasons given for the development of idiopathic forms of Parkinson’s disease (PD), copper imbalance has been identified as a factor, and PD is often referred to as a copper-mediated disorder. More than 640 papers have been devoted to the relationship between PD a...
Saved in:
| Published in: | Antioxidants Vol. 12; no. 9; p. 1654 |
|---|---|
| Main Authors: | , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
Basel
MDPI AG
22-08-2023
MDPI |
| Subjects: | |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Abstract | In the last 15 years, among the many reasons given for the development of idiopathic forms of Parkinson’s disease (PD), copper imbalance has been identified as a factor, and PD is often referred to as a copper-mediated disorder. More than 640 papers have been devoted to the relationship between PD and copper status in the blood, which include the following markers: total copper concentration, enzymatic ceruloplasmin (Cp) concentration, Cp protein level, and non-ceruloplasmin copper level. Most studies measure only one of these markers. Therefore, the existence of a correlation between copper status and the development of PD is still debated. Based on data from the published literature, meta-analysis, and our own research, it is clear that there is a connection between the development of PD symptoms and the number of copper atoms, which are weakly associated with the ceruloplasmin molecule. In this work, the link between the risk of developing PD and various inborn errors related to copper metabolism, leading to decreased levels of oxidase ceruloplasmin in the circulation and cerebrospinal fluid, is discussed. |
|---|---|
| AbstractList | In the last 15 years, among the many reasons given for the development of idiopathic forms of Parkinson’s disease (PD), copper imbalance has been identified as a factor, and PD is often referred to as a copper-mediated disorder. More than 640 papers have been devoted to the relationship between PD and copper status in the blood, which include the following markers: total copper concentration, enzymatic ceruloplasmin (Cp) concentration, Cp protein level, and non-ceruloplasmin copper level. Most studies measure only one of these markers. Therefore, the existence of a correlation between copper status and the development of PD is still debated. Based on data from the published literature, meta-analysis, and our own research, it is clear that there is a connection between the development of PD symptoms and the number of copper atoms, which are weakly associated with the ceruloplasmin molecule. In this work, the link between the risk of developing PD and various inborn errors related to copper metabolism, leading to decreased levels of oxidase ceruloplasmin in the circulation and cerebrospinal fluid, is discussed. |
| Audience | Academic |
| Author | Muruzheva, Zamira M Babich, Polina S Karpenko, Marina N Ilyechova, Ekaterina Yu Puchkova, Ludmila V |
| AuthorAffiliation | 1 I.P. Pavlov Department of Physiology, Research Institute of Experimental Medicine, 197376 St. Petersburg, Russia; mnkarpenko@mail.ru (M.N.K.); zamira.muruzheva@mail.ru (Z.M.M.) 2 Institute of Biomedical Systems and Biotechnology, Peter the Great St. Petersburg Polytechnic University, 195251 St. Petersburg, Russia; puchkovalv@yandex.ru 3 State Budgetary Institution of Health Care “Leningrad Regional Clinical Hospital”, 194291 St. Petersburg, Russia 5 Department of Molecular Genetics, Research Institute of Experimental Medicine, 197376 St. Petersburg, Russia 6 Department of Zoology and Genetics, Faculty of Biology, Herzen State Pedagogical University of Russia, 191186 St. Petersburg, Russia; babich.polina@gmail.com 4 Research Center of Advanced Functional Materials and Laser Communication Systems, ADTS Institute, ITMO University, 197101 St. Petersburg, Russia |
| AuthorAffiliation_xml | – name: 6 Department of Zoology and Genetics, Faculty of Biology, Herzen State Pedagogical University of Russia, 191186 St. Petersburg, Russia; babich.polina@gmail.com – name: 1 I.P. Pavlov Department of Physiology, Research Institute of Experimental Medicine, 197376 St. Petersburg, Russia; mnkarpenko@mail.ru (M.N.K.); zamira.muruzheva@mail.ru (Z.M.M.) – name: 5 Department of Molecular Genetics, Research Institute of Experimental Medicine, 197376 St. Petersburg, Russia – name: 4 Research Center of Advanced Functional Materials and Laser Communication Systems, ADTS Institute, ITMO University, 197101 St. Petersburg, Russia – name: 2 Institute of Biomedical Systems and Biotechnology, Peter the Great St. Petersburg Polytechnic University, 195251 St. Petersburg, Russia; puchkovalv@yandex.ru – name: 3 State Budgetary Institution of Health Care “Leningrad Regional Clinical Hospital”, 194291 St. Petersburg, Russia |
| Author_xml | – sequence: 1 givenname: Marina N. surname: Karpenko fullname: Karpenko, Marina N. – sequence: 2 givenname: Zamira M. orcidid: 0000-0003-2789-8431 surname: Muruzheva fullname: Muruzheva, Zamira M. – sequence: 3 givenname: Ekaterina Yu orcidid: 0000-0002-5623-2156 surname: Ilyechova fullname: Ilyechova, Ekaterina Yu – sequence: 4 givenname: Polina S. surname: Babich fullname: Babich, Polina S. – sequence: 5 givenname: Ludmila V. orcidid: 0000-0003-0958-2812 surname: Puchkova fullname: Puchkova, Ludmila V. |
| BookMark | eNpdks9vFCEUxyemJtbaq2cSL162AjMww8ls1qpNmtj440wYeOyynYERmNXe-m_03_MvkXYbdYUD5Mv3fd575D2vjnzwUFUvCT6ra4HfKJ9d-EkoFoSz5kl1THHLF7Wg5Oif-7PqNKUtLkuQusPiuLLL3oc4qsFlBwk5j1ZhmiCiL1nlOaFlSkE7lcGgHy5vkPLofIDdg_DZpWsULLpS8dr5FPyv27uErjbgQ76ZAL2DHQxhGsHnF9VTq4YEp4_nSfXt_fnX1cfF5acPF6vl5UIzTPLCtI0lVivMeo1bYrTQVLei14zqBhvNgBuKGWXGKMENwxy4ta1QlHEjmK1Pqos91wS1lVN0o4o3MignH4QQ11LF7PQAkhcm01jgnnYN7ohoWou54aTkFcyQwnq7Z01zP4LRpY2ohgPo4Yt3G7kOO0nuK-QNK4TXj4QYvs-Qshxd0jAMykOYk6Rdi0lTM4qL9dV_1m2Yoy9_VVxcUFrThhfX2d61VqUD520oiXXZBkany0RYV_Rly0sEw233N0DHkFIE-6d8guX94MjDwal_A170umw |
| CitedBy_id | crossref_primary_10_1007_s00432_024_05641_5 |
| Cites_doi | 10.1002/jmri.27680 10.1002/mds.21066 10.1002/ana.25292 10.1186/s13024-015-0055-2 10.1053/j.gastro.2018.11.032 10.1007/s00018-023-04781-0 10.1002/iub.1618 10.1007/978-981-15-4272-5_2 10.1016/j.jhazmat.2023.131093 10.1007/s12291-009-0017-y 10.1038/nchembio.2098 10.1016/j.jtemb.2007.04.003 10.1073/pnas.1902958116 10.1038/ng0193-20 10.3390/ijms21072612 10.1016/j.ympev.2019.106571 10.1007/s00216-005-0264-6 10.1007/s10571-020-00849-8 10.1007/s00702-004-0124-0 10.1080/15257770.2022.2052314 10.1371/journal.pone.0140797 10.3390/antiox5030025 10.1016/0378-4274(95)03444-7 10.1039/C7MT00244K 10.1039/c0mt00006j 10.1016/S0306-4522(03)00325-7 10.1046/j.1471-4159.1994.63041551.x 10.1371/journal.pgen.1010558 10.1039/C7DT03242K 10.1039/d0mt00132e 10.1007/s00775-019-01737-3 10.2174/1874609807666140805123621 10.2174/0929867053764635 10.1054/mehy.2000.1134 10.1016/j.jinorgbio.2021.111424 10.1152/ajpgi.90489.2008 10.1007/s00415-009-0063-7 10.3390/biomedicines9040391 10.1016/j.neulet.2021.135873 10.1016/j.jinorgbio.2012.07.003 10.1155/2016/3612589 10.1161/01.RES.0000043500.03647.81 10.3389/fnagi.2013.00037 10.3390/ijms232213850 10.20944/preprints202207.0464.v1 10.1016/j.pneurobio.2014.01.002 10.1093/hmg/ddy059 10.1111/jnc.13425 10.1126/science.276.5321.2045 10.1074/jbc.RA118.006987 10.1136/postgradmedj-2017-135381 10.1016/j.neulet.2018.09.034 10.1016/j.abb.2004.10.030 10.1016/j.parkreldis.2014.08.016 10.1016/S1474-4422(14)70190-5 10.1074/jbc.REV120.008207 10.3390/biom12050714 10.1007/s00335-022-09971-y 10.3390/jpm9030041 10.4331/wjbc.v5.i2.204 10.1006/bbrc.2002.6423 10.1038/s41568-021-00417-2 10.3389/fnmol.2021.797833 10.1258/000456303763046021 10.1196/annals.1306.024 10.1093/brain/awq319 10.1007/s13760-020-01473-5 10.3945/an.112.003210 10.2147/DMSO.S346648 10.1074/jbc.M804079200 10.1128/MCB.23.5.1509-1519.2003 10.1126/science.1195227 10.1021/cr900104z 10.1002/ana.23817 10.1097/RLU.0000000000001734 10.1007/s00894-018-3592-0 10.4103/aian.AIAN_419_20 10.3390/ijerph13090881 10.1016/j.tracli.2018.08.006 10.1021/acs.biochem.3c00005 10.1002/jat.2854 10.1242/jcs.240523 10.3109/00207454.2015.1020113 10.1038/ng0193-14 10.1001/jama.281.4.341 10.1039/C4MT00107A 10.1016/0304-4165(77)90064-2 10.1016/j.neuroscience.2019.01.006 10.1007/s00216-004-2697-8 10.1039/D1DT02878B 10.4103/2277-8632.158577 10.1093/jn/109.11.1979 10.3390/biom11070960 10.1016/j.redox.2018.05.013 10.20944/preprints201809.0161.v1 10.1177/1087057109355708 10.1038/nrn.2016.138 10.1007/s10534-022-00370-z 10.4067/S0716-97602006000100007 10.1016/S0006-8993(96)00782-2 10.1002/mdc3.12568 10.1002/ajmg.10196 10.1016/j.cub.2021.03.054 10.3390/ijms21155536 10.1080/00365513.2020.1821397 10.1038/ncomms10640 10.31083/j.jin.2019.03.127 10.1515/bchm3.1989.370.2.673 10.2174/1567205018666211022085755 10.1007/s12035-016-0193-8 10.1016/j.nbd.2011.12.046 10.1093/mtomcs/mfac039 10.1016/j.parkreldis.2006.03.009 10.1146/annurev-genet-030620-102906 10.1159/000330538 10.3390/ijms22094591 10.3389/fnagi.2022.888942 10.20944/preprints202203.0274.v1 10.1038/s41598-020-72447-z 10.1038/ng0193-7 10.1074/jbc.M114.558494 10.1155/2020/4293071 10.1016/j.mehy.2015.10.009 10.1111/j.1432-1033.1981.tb06194.x 10.1016/j.brainres.2008.10.056 10.1093/hmg/11.2.165 10.1016/j.parkreldis.2018.05.022 10.1007/s11064-017-2454-y 10.2174/0929867325666171129124616 10.1126/science.abf0529 10.1023/B:DOBI.0000039476.31868.bc 10.1152/ajpcell.00054.2010 10.1007/978-3-319-60189-2_3 10.1128/MCB.21.19.6440-6449.2001 10.1007/s00424-020-02412-2 10.1016/0022-510X(92)90127-7 10.1016/j.neures.2017.11.011 10.1016/j.nbd.2021.105474 10.1016/j.parkreldis.2016.12.010 10.1186/1752-0509-1-S1-P54 10.1016/B978-0-444-63625-6.00003-3 10.1016/S0140-6736(21)00218-X 10.1016/j.jtemb.2014.03.006 10.1016/S1357-2725(98)00073-9 10.1038/s41572-018-0018-3 10.1007/s10571-019-00734-z 10.1101/cshperspect.a009258 10.3390/ijms21239259 10.1002/ajmg.b.32723 10.2131/jts.37.1207 10.1007/s11033-019-04791-x 10.1007/s00415-013-7003-2 10.1016/j.jinorgbio.2021.111478 10.3389/fnagi.2014.00089 10.1016/j.biocel.2008.08.001 10.1371/journal.pone.0149516 10.1007/s10534-017-0058-2 10.3390/ijms24076377 10.1002/cphy.c170045 10.1126/science.284.5415.805 10.3389/fcell.2021.612476 10.1038/5979 10.1007/s10495-021-01692-y 10.1093/mtomcs/mfac006 10.1093/hmg/ddac156 10.1016/j.cbpb.2005.12.010 10.1016/j.jinorgbio.2011.11.024 10.1134/S2079978016010027 10.1007/s12011-008-8110-2 10.1016/j.bbamcr.2020.118867 10.1146/annurev.nutr.22.012502.114457 10.1155/2014/147251 10.1093/qjmed/hcr229 10.1007/s10719-015-9626-2 10.1038/s41419-023-05639-w 10.4103/1673-5374.320965 10.1016/j.pneurobio.2020.101890 10.1016/j.bbagen.2014.01.011 10.1016/j.tips.2021.05.001 10.1039/C7MT00184C 10.1111/cge.14289 10.1309/AJCP7Z9KBFINVGYF 10.1038/nrn.2017.62 10.1177/153537020623100903 10.1046/j.1471-4159.1997.69051904.x 10.1002/(SICI)1097-4547(19981015)54:2<147::AID-JNR3>3.0.CO;2-E 10.1002/anie.202108961 10.1007/s12038-016-9629-6 10.1007/s00018-004-5076-x 10.1007/s00018-019-03279-y 10.1016/j.toxrep.2021.03.009 10.1074/jbc.R117.000176 10.1002/ana.25441 10.1021/acs.inorgchem.2c03753 10.1038/s41467-019-08858-y 10.1074/jbc.M413840200 10.3389/fmolb.2021.711227 10.1016/j.neulet.2020.135297 10.1007/s007750050380 10.1021/ac040184q 10.3390/ijms22020663 10.1016/j.bbamcr.2012.01.013 10.1523/JNEUROSCI.2838-11.2011 10.1093/hmg/3.9.1647 10.3945/jn.109.117531 10.3390/genes13122361 10.1038/nn.3350 10.1095/biolreprod61.4.1042 10.1007/s11910-017-0780-8 10.1016/j.pharmthera.2005.11.004 10.1016/j.cger.2019.08.002 10.1007/s00775-012-0932-x 10.3233/JAD-171074 10.1038/ng1293-327 10.1002/humu.21277 10.3390/biom10020195 10.1083/jcb.202012095 10.1016/j.brainres.2009.11.085 10.1016/j.neulet.2019.05.015 10.1002/jnr.22404 10.1016/j.jnutbio.2006.11.005 10.21037/atm.2019.03.02 10.1016/j.cbi.2022.110173 10.1126/science.1140481 10.1186/s13104-018-3324-7 10.3945/ajcn.2009.27230E 10.1023/A:1021245902195 10.1159/000440865 10.1016/j.jtemb.2017.11.005 10.18632/oncotarget.5779 10.2741/4665 10.1073/pnas.83.10.3257 10.1074/jbc.275.11.7455 10.1007/978-981-10-5717-5_4 10.1017/cjn.2016.327 10.1074/jbc.275.6.4305 10.1007/s00702-018-1889-x 10.1038/ejhg.2009.187 10.1007/s10534-006-9074-3 10.1021/bi00398a034 10.1016/j.jns.2011.03.035 10.3390/ijms221910704 10.20944/preprints201811.0279.v1 10.1071/EA9830024 10.1007/s10517-018-4039-4 10.1016/bs.acc.2019.12.001 10.1039/C8MT00280K 10.1016/j.neuro.2019.07.007 10.1039/C8MT00274F 10.1016/j.clinbiochem.2007.04.002 10.1016/j.abb.2008.05.005 10.1016/S1474-4422(16)30230-7 10.1016/j.parkreldis.2017.07.033 10.1186/s13024-019-0336-2 10.1016/j.mito.2019.10.008 10.1523/JNEUROSCI.3768-11.2011 10.2147/JMDH.S93454 10.3390/genes12071006 10.1177/104063871002200221 10.1006/bbrc.1995.1437 10.1039/C6MT00079G 10.3390/ijms23031435 10.1007/978-3-211-33328-0_24 10.1039/C6MT00103C 10.1007/s10571-021-01039-w 10.1007/s12291-016-0614-5 10.1042/bj3170051 10.1016/B978-0-444-59565-2.00045-9 10.3181/00379727-210-43929 10.1136/jmedgenet-2017-105047 10.1371/journal.pone.0038327 10.1371/currents.tol.574bcb0f133fe52835911abc4e296141 10.5387/fms.59.76 10.1038/77060 10.1016/j.jtemb.2016.12.013 10.1016/j.bpc.2004.12.014 10.1038/s10038-022-01058-5 |
| ContentType | Journal Article |
| Copyright | COPYRIGHT 2023 MDPI AG 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. 2023 by the authors. 2023 |
| Copyright_xml | – notice: COPYRIGHT 2023 MDPI AG – notice: 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. – notice: 2023 by the authors. 2023 |
| DBID | AAYXX CITATION 7QR 7T5 7TO 8FD 8FE 8FH ABUWG AFKRA AZQEC BBNVY BENPR BHPHI CCPQU DWQXO FR3 GNUQQ H94 HCIFZ LK8 M7P P64 PIMPY PQEST PQQKQ PQUKI PRINS 7X8 5PM DOA |
| DOI | 10.3390/antiox12091654 |
| DatabaseName | CrossRef Chemoreception Abstracts Immunology Abstracts Oncogenes and Growth Factors Abstracts Technology Research Database ProQuest SciTech Collection ProQuest Natural Science Collection ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials Biological Science Collection AUTh Library subscriptions: ProQuest Central ProQuest Natural Science Collection ProQuest One Community College ProQuest Central Engineering Research Database ProQuest Central Student AIDS and Cancer Research Abstracts SciTech Premium Collection (Proquest) (PQ_SDU_P3) Biological Sciences Biological Science Database Biotechnology and BioEngineering Abstracts Publicly Available Content Database (Proquest) (PQ_SDU_P3) ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China MEDLINE - Academic PubMed Central (Full Participant titles) Directory of Open Access Journals |
| DatabaseTitle | CrossRef Publicly Available Content Database ProQuest Central Student Oncogenes and Growth Factors Abstracts Technology Research Database ProQuest Central Essentials ProQuest Central (Alumni Edition) SciTech Premium Collection ProQuest One Community College ProQuest Natural Science Collection ProQuest Central China ProQuest Central Natural Science Collection ProQuest Central Korea Biological Science Collection AIDS and Cancer Research Abstracts Chemoreception Abstracts ProQuest Biological Science Collection ProQuest One Academic Eastern Edition Biological Science Database ProQuest SciTech Collection Biotechnology and BioEngineering Abstracts ProQuest One Academic UKI Edition Immunology Abstracts Engineering Research Database ProQuest One Academic MEDLINE - Academic |
| DatabaseTitleList | Publicly Available Content Database CrossRef |
| Database_xml | – sequence: 1 dbid: DOA name: Directory of Open Access Journals url: http://www.doaj.org/ sourceTypes: Open Website |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Engineering |
| EISSN | 2076-3921 |
| ExternalDocumentID | oai_doaj_org_article_652c5c090b284081947f06d6171d95d1 A766925078 10_3390_antiox12091654 |
| GeographicLocations | Russia |
| GeographicLocations_xml | – name: Russia |
| GrantInformation_xml | – fundername: Russian Science Foundation grantid: 22-24-00762 – fundername: Ministry of Education of RF grantid: VRFY-2023-0009 – fundername: Russian Foundation for Basic Research grantid: 20-515-7813 |
| GroupedDBID | 53G 5VS 8FE 8FH AADQD AAFWJ AAHBH AAYXX ADBBV AFKRA AFPKN AFZYC ALMA_UNASSIGNED_HOLDINGS AOIJS BBNVY BCNDV BENPR BHPHI CCPQU CITATION GROUPED_DOAJ HCIFZ HYE IAO ITC KQ8 LK8 M48 M7P MODMG M~E OK1 PGMZT PIMPY PROAC RPM 7QR 7T5 7TO 8FD ABUWG AZQEC DWQXO FR3 GNUQQ H94 P64 PQEST PQQKQ PQUKI PRINS 7X8 5PM |
| ID | FETCH-LOGICAL-c501t-d74f1fca05bc071dc9c2c79bc52c40dc5e6d20525dda96d506e6ff79a256d95f3 |
| IEDL.DBID | RPM |
| ISSN | 2076-3921 |
| IngestDate | Tue Oct 22 15:13:19 EDT 2024 Tue Sep 17 21:29:20 EDT 2024 Fri Oct 25 02:05:45 EDT 2024 Thu Oct 10 19:20:41 EDT 2024 Tue Nov 12 23:54:04 EST 2024 Fri Nov 22 01:29:52 EST 2024 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 9 |
| Language | English |
| License | Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c501t-d74f1fca05bc071dc9c2c79bc52c40dc5e6d20525dda96d506e6ff79a256d95f3 |
| Notes | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 |
| ORCID | 0000-0002-5623-2156 0000-0003-0958-2812 0000-0003-2789-8431 |
| OpenAccessLink | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525645/ |
| PQID | 2869223246 |
| PQPubID | 2032435 |
| ParticipantIDs | doaj_primary_oai_doaj_org_article_652c5c090b284081947f06d6171d95d1 pubmedcentral_primary_oai_pubmedcentral_nih_gov_10525645 proquest_miscellaneous_2870143520 proquest_journals_2869223246 gale_infotracacademiconefile_A766925078 crossref_primary_10_3390_antiox12091654 |
| PublicationCentury | 2000 |
| PublicationDate | 20230822 |
| PublicationDateYYYYMMDD | 2023-08-22 |
| PublicationDate_xml | – month: 8 year: 2023 text: 20230822 day: 22 |
| PublicationDecade | 2020 |
| PublicationPlace | Basel |
| PublicationPlace_xml | – name: Basel |
| PublicationTitle | Antioxidants |
| PublicationYear | 2023 |
| Publisher | MDPI AG MDPI |
| Publisher_xml | – name: MDPI AG – name: MDPI |
| References | ref_137 Liu (ref_235) 2019; 18 ref_138 Daymond (ref_195) 2020; 80 Mariani (ref_280) 2016; 126 ref_90 Zhang (ref_3) 2018; 55 Dandana (ref_50) 2016; 83 Sampath (ref_147) 2003; 23 Kaler (ref_61) 2013; 113 Gupta (ref_190) 2023; 80 ref_255 Singh (ref_183) 2020; 54 Arredondo (ref_198) 2008; 123 Park (ref_222) 2016; 17 Squitti (ref_201) 2018; 63 Mains (ref_213) 2010; 88 Cherian (ref_25) 2020; 120 Petrukhin (ref_260) 1994; 3 Demchenko (ref_234) 2002; 91 ref_126 Squitti (ref_199) 2021; 18 ref_125 Schulte (ref_97) 2023; 62 Li (ref_27) 2021; 9 Squitti (ref_200) 2018; 45 Xu (ref_144) 2004; 1012 Faxuan (ref_151) 2012; 37 Lutsenko (ref_252) 2019; 24 Panicker (ref_28) 2021; 220 Vasin (ref_166) 2004; 397 Chege (ref_268) 2014; 6 Gangania (ref_271) 2017; 32 Fan (ref_19) 2020; 2020 Platonova (ref_122) 2005; 2 Mezzaroba (ref_54) 2019; 74 Prohaska (ref_210) 2005; 434 ref_71 Ayton (ref_220) 2013; 73 Karpenko (ref_132) 2018; 164 Vroegindeweij (ref_142) 2017; 36 Fatemi (ref_128) 2002; 34 Dame (ref_158) 2023; 103 Chen (ref_114) 2021; 60 Fan (ref_30) 2022; 14 Genoud (ref_216) 2017; 9 Forte (ref_275) 2004; 111 ref_281 Zogzas (ref_64) 2017; 18 Jackson (ref_242) 2006; 384 Patel (ref_270) 2018; 27 Fattah (ref_276) 2020; 736 McMillin (ref_191) 2009; 131 Waggoner (ref_227) 2000; 275 Barbariga (ref_218) 2015; 10 Borges (ref_145) 2019; 180 Koschinsky (ref_165) 1987; 26 Bjorklund (ref_35) 2018; 25 Laguna (ref_214) 2019; 10 Fukushima (ref_277) 2013; 59 Twoney (ref_197) 2007; 40 Dickson (ref_2) 2012; 2 Rothuizen (ref_155) 2002; 11 Barbariga (ref_219) 2020; 10 Abad (ref_236) 2014; 289 ref_263 Funayama (ref_18) 2023; 68 ref_143 ref_267 Jin (ref_284) 2011; 134 Braiterman (ref_124) 2009; 296 Tarohda (ref_249) 2004; 380 Cobine (ref_112) 2021; 1868 Formigari (ref_79) 2013; 33 Baltaci (ref_55) 2018; 43 Schapira (ref_4) 2017; 18 Su (ref_159) 1982; 243 Bartee (ref_123) 2007; 20 Qin (ref_86) 2017; 46 Helman (ref_119) 2023; 36 Besold (ref_98) 2021; 219 Mason (ref_226) 1979; 109 Linder (ref_246) 1977; 499 Hatori (ref_254) 2016; 7 Cerri (ref_17) 2019; 9 Alonso (ref_135) 2017; 44 Echeverria (ref_13) 2017; 54 Prashanth (ref_95) 2015; 4 Salzer (ref_164) 1998; 54 Prohaska (ref_209) 1994; 63 Chen (ref_94) 2020; 472 Belaidi (ref_179) 2016; 139 Rigiracciolo (ref_73) 2015; 6 Zimnicka (ref_96) 2011; 300 Bloem (ref_14) 2021; 397 Prasad (ref_63) 2013; 4 Jomova (ref_72) 2022; 367 Quarles (ref_193) 2020; 12 Arnal (ref_205) 2010; 1319 Doguer (ref_68) 2018; 8 Lu (ref_31) 2020; 1207 Solioz (ref_100) 2002; 291 Vulpe (ref_174) 1999; 21 ref_202 ref_204 Alam (ref_40) 2022; 14 Chen (ref_80) 2021; 26 Tapryal (ref_148) 2009; 284 ref_206 Bharucha (ref_274) 2008; 255 Coan (ref_105) 1989; 370 Miranda (ref_241) 2010; 22 Chelly (ref_256) 1993; 3 Herrero (ref_282) 1992; 112 Johnson (ref_133) 2001; 56 Niemiec (ref_146) 2012; 1823 Bonnemaison (ref_237) 2016; 8 Mubarak (ref_269) 2023; 62 Sechi (ref_134) 2007; 13 Kumaresan (ref_5) 2021; 13 Rosselli (ref_9) 2021; 37 Mazumder (ref_150) 2001; 21 Liu (ref_181) 2022; 15 Platonova (ref_244) 2007; 21 Hellman (ref_120) 2002; 22 ref_116 Xu (ref_285) 2018; 125 Prohaska (ref_211) 1995; 210 Choi (ref_247) 2009; 1248 Raj (ref_41) 2021; 753 Lubbe (ref_22) 2014; 261 Scheiber (ref_248) 2014; 116 Choudhuri (ref_288) 1996; 84 Zaitsev (ref_171) 1999; 4 ref_113 Cavaleri (ref_230) 2015; 85 Liu (ref_104) 2007; 18 Woimant (ref_194) 2019; 7 Falcone (ref_203) 2021; 221 Bouchaoui (ref_66) 2021; 196 Mathie (ref_89) 2006; 111 Lutsenko (ref_57) 2021; 134 Montinaro (ref_16) 2022; 17 ref_225 Ling (ref_286) 2011; 66 ref_229 Kim (ref_239) 2002; 108 Thiele (ref_110) 2015; 31 Yang (ref_153) 2022; 41 ref_109 Oury (ref_232) 1996; 317 Ackerman (ref_75) 2018; 293 Litwin (ref_117) 2018; 4 Musci (ref_188) 2014; 5 Mouradian (ref_141) 2012; 46 ref_223 Wang (ref_46) 2022; 42 Narita (ref_108) 1997; 69 Chang (ref_264) 2017; 142 Lutsenko (ref_102) 2008; 476 Burre (ref_43) 2010; 329 Wada (ref_53) 2004; 47 Tsvetkov (ref_88) 2022; 375 Walshe (ref_192) 2012; 105 Bandmann (ref_217) 2015; 14 Yuan (ref_81) 2017; 9 Platonova (ref_167) 2005; 115 Ilyechova (ref_208) 2014; 6 Vulpe (ref_257) 1993; 3 ref_12 Maltais (ref_184) 2003; 121 Singh (ref_32) 2014; 7 Dhivya (ref_83) 2016; 41 Fortna (ref_163) 1999; 61 Zhang (ref_52) 2017; 1005 Nikam (ref_15) 2009; 24 Rae (ref_93) 1999; 284 Abbas (ref_21) 2017; 5 Ghosh (ref_238) 2019; 706 Mariani (ref_287) 2013; 5 Roy (ref_154) 2023; 34 Olivieri (ref_221) 2011; 31 Nuytemans (ref_23) 2010; 31 ref_29 Rubino (ref_91) 2012; 107 Shimura (ref_26) 2000; 25 Roemhild (ref_62) 2021; 42 Boal (ref_92) 2009; 109 Aissi (ref_273) 2013; 91 Schulz (ref_185) 2011; 31 Kim (ref_279) 2018; 55 Clerc (ref_170) 2016; 33 Orenstein (ref_45) 2013; 16 Platonova (ref_168) 2017; 43 Jin (ref_152) 2018; 687 Kristinsson (ref_130) 2012; 8 Haag (ref_85) 2020; 77 Lei (ref_266) 2021; 96 Ullah (ref_10) 2021; 8 Miyake (ref_60) 2011; 306 Gaitskhoki (ref_169) 1981; 115 Zatulovskiy (ref_189) 2007; 1 Guan (ref_65) 2021; 54 Loeffler (ref_215) 1996; 738 Calvo (ref_289) 2017; 69 Puschmann (ref_24) 2017; 17 Barnes (ref_251) 2005; 280 Kotuniak (ref_103) 2021; 51 Walshe (ref_196) 2003; 40 Schirinzi (ref_278) 2016; 2016 Yang (ref_160) 1986; 83 Mazumder (ref_149) 2006; 39 Weiss (ref_245) 1985; 249 Zhang (ref_37) 2010; 15 Zhao (ref_139) 2014; 20 Harvey (ref_127) 2009; 89 Chen (ref_175) 2010; 140 Li (ref_231) 2021; 14 Havekes (ref_44) 2020; 52 Kang (ref_99) 2006; 231 Rahman (ref_47) 2019; 401 Nakamura (ref_173) 2005; 62 Terada (ref_129) 1998; 30 Daimon (ref_161) 1995; 208 Sassone (ref_48) 2021; 41 ref_172 ref_56 (ref_101) 2010; 18 Zatulovskiy (ref_228) 2012; 116 Ascherio (ref_8) 2016; 15 Valko (ref_36) 2005; 12 Merry (ref_59) 1983; 23 Montes (ref_67) 2014; 2014 ref_180 ref_182 Leinweber (ref_136) 2006; 21 Simon (ref_1) 2020; 36 Ruiz (ref_74) 2021; 8 Lutsenko (ref_253) 2010; 2 Patel (ref_162) 2000; 275 Stefaniak (ref_107) 2018; 10 Krishnamoorthy (ref_84) 2016; 12 Kobylecki (ref_20) 2018; 84 ref_69 Vashchenko (ref_177) 2012; 17 Muller (ref_77) 2009; 41 Brissot (ref_178) 2019; 26 Ilyechova (ref_131) 2018; 135 Dickson (ref_7) 2018; 46 Li (ref_115) 2017; 30 Becker (ref_243) 2005; 77 Tripathi (ref_290) 2021; 24 Laukkanen (ref_233) 2016; 2016 Kelly (ref_118) 2018; 94 Zanardi (ref_224) 2021; 158 Song (ref_283) 2017; 42 Tsang (ref_76) 2021; 31 Gioilli (ref_207) 2022; 14 Bull (ref_259) 1993; 5 Polymeropoulos (ref_42) 1997; 276 Eid (ref_187) 2014; 1840 Ge (ref_261) 2022; 22 Kim (ref_140) 2007; 317 Chen (ref_58) 2018; 23 Puchkova (ref_250) 1999; 30 Wu (ref_78) 2019; 11 Linder (ref_106) 2016; 8 Polishchuk (ref_87) 2019; 156 Chen (ref_176) 2018; 17 Mercer (ref_258) 1993; 3 Croft (ref_82) 2019; 294 Chen (ref_262) 2023; 14 ref_186 Dudev (ref_39) 2018; 24 Ramaiah (ref_240) 2019; 139 Skvortsov (ref_38) 2023; 451 Prohaska (ref_212) 2006; 143 Ojha (ref_265) 2016; 9 Bougea (ref_11) 2020; 96 Sanyal (ref_272) 2020; 40 Goldman (ref_34) 2019; 85 Tishchenko (ref_70) 2016; 6 Do (ref_49) 2019; 14 Barros (ref_111) 2020; 50 Mori (ref_51) 2019; 116 Kumari (ref_156) 2019; 46 Tanner (ref_33) 1999; 281 Puchkova (ref_121) 1994; 59 Batzios (ref_157) 2022; 31 ref_6 |
| References_xml | – volume: 54 start-page: 1098 year: 2021 ident: ref_65 article-title: Serum ceruloplasmin depletion is associated with magnetic resonance evidence of widespread accumulation of brain iron in Parkinson’s disease publication-title: J. Magn. Reson. Imaging doi: 10.1002/jmri.27680 contributor: fullname: Guan – volume: 21 start-page: 1789 year: 2006 ident: ref_136 article-title: Prevalence of the H1069Q mutation in ATP7B in discordant pairs with early-onset Parkinson’s disease publication-title: Mov. Disord. doi: 10.1002/mds.21066 contributor: fullname: Leinweber – volume: 84 start-page: 178 year: 2018 ident: ref_20 article-title: Plasma urate and risk of Parkinson’s disease: A mendelian randomization study publication-title: Ann. Neurol. doi: 10.1002/ana.25292 contributor: fullname: Kobylecki – volume: 10 start-page: 59 year: 2015 ident: ref_218 article-title: Ceruloplasmin functional changes in Parkinson’s disease-cerebrospinal fluid publication-title: Mol. Neurodegener. doi: 10.1186/s13024-015-0055-2 contributor: fullname: Barbariga – volume: 156 start-page: 1173 year: 2019 ident: ref_87 article-title: Activation of autophagy, observed in liver tissues from patients with Wilson disease and from ATP7B-deficient animals, protects hepatocytes from copper-induced apoptosis publication-title: Gastroenterology doi: 10.1053/j.gastro.2018.11.032 contributor: fullname: Polishchuk – volume: 80 start-page: 130 year: 2023 ident: ref_190 article-title: Moonlighting enzymes: When cellular context defines specificity publication-title: Cell. Mol. Life Sci. doi: 10.1007/s00018-023-04781-0 contributor: fullname: Gupta – volume: 69 start-page: 236 year: 2017 ident: ref_289 article-title: Copper metallothioneins publication-title: Iubmb Life doi: 10.1002/iub.1618 contributor: fullname: Calvo – volume: 1207 start-page: 21 year: 2020 ident: ref_31 article-title: Autophagy and Parkinson’s Disease publication-title: Adv. Exp. Med. Biol. doi: 10.1007/978-981-15-4272-5_2 contributor: fullname: Lu – volume: 451 start-page: 131093 year: 2023 ident: ref_38 article-title: Chemical background of silver nanoparticles interfering with mammalian copper metabolism publication-title: J. Hazard. Mater. doi: 10.1016/j.jhazmat.2023.131093 contributor: fullname: Skvortsov – volume: 24 start-page: 98 year: 2009 ident: ref_15 article-title: Oxidative stress in Parkinson’s disease publication-title: Indian J. Clin. Biochem. doi: 10.1007/s12291-009-0017-y contributor: fullname: Nikam – volume: 12 start-page: 586 year: 2016 ident: ref_84 article-title: Copper regulates cyclic-AMP-dependent lipolysis publication-title: Nat. Chem. Biol. doi: 10.1038/nchembio.2098 contributor: fullname: Krishnamoorthy – volume: 21 start-page: 184 year: 2007 ident: ref_244 article-title: Milk ceruloplasmin is a valuable source of nutrient copper ions for mammalian newborns publication-title: J. Trace Elem. Med. Biol. doi: 10.1016/j.jtemb.2007.04.003 contributor: fullname: Platonova – volume: 116 start-page: 20689 year: 2019 ident: ref_51 article-title: Parkinson’s disease-associated iPLA2-VIA/PLA2G6 regulates neuronal functions and α-synuclein stability through membrane remodeling publication-title: Proc. Natl. Acad. Sci. USA doi: 10.1073/pnas.1902958116 contributor: fullname: Mori – volume: 3 start-page: 20 year: 1993 ident: ref_258 article-title: Isolation of a partial candidate gene for Menkes disease by positional cloning publication-title: Nat. Genet. doi: 10.1038/ng0193-20 contributor: fullname: Mercer – ident: ref_263 doi: 10.3390/ijms21072612 – volume: 139 start-page: 106571 year: 2019 ident: ref_240 article-title: Evolution and functional classification of mammalian copper amine oxidases publication-title: Mol. Phylogenet. Evol. doi: 10.1016/j.ympev.2019.106571 contributor: fullname: Ramaiah – volume: 384 start-page: 951 year: 2006 ident: ref_242 article-title: Elemental mapping and quantitative analysis of Cu, Zn, and Fe in rat brain sections by laser ablation ICP-MS publication-title: Anal. Bioanal. Chem. doi: 10.1007/s00216-005-0264-6 contributor: fullname: Jackson – volume: 41 start-page: 199 year: 2021 ident: ref_48 article-title: The Role of VPS35 in the Pathobiology of Parkinson’s Disease publication-title: Cell. Mol. Neurobiol. doi: 10.1007/s10571-020-00849-8 contributor: fullname: Sassone – volume: 111 start-page: 1031 year: 2004 ident: ref_275 article-title: Trace and major elements in whole blood, serum, cerebrospinal fluid and urine of patients with Parkinson’s disease publication-title: J. Neural Transm. doi: 10.1007/s00702-004-0124-0 contributor: fullname: Forte – volume: 41 start-page: 474 year: 2022 ident: ref_153 article-title: Ceruloplasmin inhibits the proliferation, migration and invasion of nasopharyngeal carcinoma cells and is negatively regulated by miR-543 publication-title: Nucleosides Nucleotides Nucleic Acids doi: 10.1080/15257770.2022.2052314 contributor: fullname: Yang – ident: ref_186 doi: 10.1371/journal.pone.0140797 – ident: ref_113 doi: 10.3390/antiox5030025 – volume: 84 start-page: 127 year: 1996 ident: ref_288 article-title: Cadmium accumulation and metallothionein expression in brain of mice at different stages of development publication-title: Toxicol. Lett. doi: 10.1016/0378-4274(95)03444-7 contributor: fullname: Choudhuri – volume: 9 start-page: 1447 year: 2017 ident: ref_216 article-title: Subcellular compartmentalisation of copper, iron, manganese, and zinc in the Parkinson’s disease brain publication-title: Metallomics doi: 10.1039/C7MT00244K contributor: fullname: Genoud – volume: 2 start-page: 596 year: 2010 ident: ref_253 article-title: Copper handling machinery of the brain publication-title: Metallomics doi: 10.1039/c0mt00006j contributor: fullname: Lutsenko – volume: 121 start-page: 73 year: 2003 ident: ref_184 article-title: The blue copper ceruloplasmin induces aggregation of newly differentiated neurons: A potential modulator of nervous system organization publication-title: Neuroscience doi: 10.1016/S0306-4522(03)00325-7 contributor: fullname: Maltais – volume: 63 start-page: 1551 year: 1994 ident: ref_209 article-title: Regional specificity in alterations of rat brain copper and catecholamines following perinatal copper deficiency publication-title: J. Neurochem. doi: 10.1046/j.1471-4159.1994.63041551.x contributor: fullname: Prohaska – ident: ref_255 doi: 10.1371/journal.pgen.1010558 – volume: 46 start-page: 16446 year: 2017 ident: ref_86 article-title: Synthesis, characterization, and anticancer activity of two mixed ligand copper(ii) complexes by regulating the VEGF/VEGFR2 signaling pathway publication-title: Dalton Trans. doi: 10.1039/C7DT03242K contributor: fullname: Qin – volume: 12 start-page: 1348 year: 2020 ident: ref_193 article-title: LC-ICP-MS method for the determination of “extractable copper” in serum publication-title: Metallomics doi: 10.1039/d0mt00132e contributor: fullname: Quarles – volume: 24 start-page: 1179 year: 2019 ident: ref_252 article-title: Copper and the brain noradrenergic system publication-title: J. Biol. Inorg. Chem. doi: 10.1007/s00775-019-01737-3 contributor: fullname: Lutsenko – volume: 7 start-page: 101 year: 2014 ident: ref_32 article-title: Gene-gene and gene-environment interaction on the risk of Parkinson’s disease publication-title: Curr. Aging Sci. doi: 10.2174/1874609807666140805123621 contributor: fullname: Singh – volume: 12 start-page: 1161 year: 2005 ident: ref_36 article-title: Metals, toxicity and oxidative stress publication-title: Curr. Med. Chem. doi: 10.2174/0929867053764635 contributor: fullname: Valko – volume: 56 start-page: 171 year: 2001 ident: ref_133 article-title: Is Parkinson’s disease the heterozygote form of Wilson’s disease: PD = 1/2 WD? publication-title: Med. Hypotheses doi: 10.1054/mehy.2000.1134 contributor: fullname: Johnson – volume: 219 start-page: 111424 year: 2021 ident: ref_98 article-title: Ceruloplasmin as a source of Cu for a fungal pathogen publication-title: J. Inorg. Biochem. doi: 10.1016/j.jinorgbio.2021.111424 contributor: fullname: Besold – volume: 296 start-page: G433 year: 2009 ident: ref_124 article-title: Apical targeting and Golgi retention signals reside within a 9-amino acid sequence in the copper-ATPase, ATP7B publication-title: Am. J. Physiol. Gastrointest. Liver Physiol. doi: 10.1152/ajpgi.90489.2008 contributor: fullname: Braiterman – volume: 255 start-page: 1957 year: 2008 ident: ref_274 article-title: Lower serum ceruloplasmin levels correlate with younger age of onset in Parkinson’s disease publication-title: J. Neurol. doi: 10.1007/s00415-009-0063-7 contributor: fullname: Bharucha – ident: ref_71 doi: 10.3390/biomedicines9040391 – volume: 753 start-page: 135873 year: 2021 ident: ref_41 article-title: Metals associated neurodegeneration in Parkinson’s disease: Insight to physiological, pathological mechanisms and management publication-title: Neurosci. Lett. doi: 10.1016/j.neulet.2021.135873 contributor: fullname: Raj – volume: 116 start-page: 88 year: 2012 ident: ref_228 article-title: Serum depletion of holo-ceruloplasmin induced by silver ions in vivo reduces uptake of cisplatin publication-title: J. Inorg. Biochem. doi: 10.1016/j.jinorgbio.2012.07.003 contributor: fullname: Zatulovskiy – volume: 2016 start-page: 3612589 year: 2016 ident: ref_233 article-title: Extracellular superoxide dismutase: Growth promoter or tumor suppressor? publication-title: Oxid. Med. Cell. Longev. doi: 10.1155/2016/3612589 contributor: fullname: Laukkanen – volume: 59 start-page: 296 year: 1994 ident: ref_121 article-title: Biosynthesis and secretion of ceruloplasmin by rat mammary cells during lactation publication-title: Biokhimiia contributor: fullname: Puchkova – volume: 91 start-page: 1031 year: 2002 ident: ref_234 article-title: Regulation of the brain’s vascular responses to oxygen publication-title: Circ. Res. doi: 10.1161/01.RES.0000043500.03647.81 contributor: fullname: Demchenko – volume: 5 start-page: 37 year: 2013 ident: ref_287 article-title: Effects of hemochromatosis and transferrin gene mutations on peripheral iron dyshomeostasis in mild cognitive impairment and Alzheimer’s and Parkinson’s diseases publication-title: Front. Aging Neurosci. doi: 10.3389/fnagi.2013.00037 contributor: fullname: Mariani – ident: ref_90 doi: 10.3390/ijms232213850 – ident: ref_109 doi: 10.20944/preprints202207.0464.v1 – volume: 116 start-page: 33 year: 2014 ident: ref_248 article-title: Metabolism and functions of copper in brain publication-title: Prog. Neurobiol. doi: 10.1016/j.pneurobio.2014.01.002 contributor: fullname: Scheiber – volume: 27 start-page: 1514 year: 2018 ident: ref_270 article-title: Alpha-synuclein inhibits Snx3-retromer-mediated retrograde recycling of iron transporters in S. cerevisiae and C. elegans models of Parkinson’s disease publication-title: Hum. Mol. Genet. doi: 10.1093/hmg/ddy059 contributor: fullname: Patel – volume: 139 start-page: 179 year: 2016 ident: ref_179 article-title: Iron neurochemistry in Alzheimer’s disease and Parkinson’s disease: Targets for therapeutics publication-title: J. Neurochem. doi: 10.1111/jnc.13425 contributor: fullname: Belaidi – volume: 276 start-page: 2045 year: 1997 ident: ref_42 article-title: Mutation in the alpha-synuclein gene identified in families with Parkinson’s disease publication-title: Science doi: 10.1126/science.276.5321.2045 contributor: fullname: Polymeropoulos – volume: 294 start-page: 5562 year: 2019 ident: ref_82 article-title: The copper-sensing transcription factor Mac1, the histone deacetylase Hst1, and nicotinic acid regulate de novo NAD+ biosynthesis in budding yeast publication-title: J. Biol. Chem. doi: 10.1074/jbc.RA118.006987 contributor: fullname: Croft – volume: 52 start-page: 325 year: 2020 ident: ref_44 article-title: The contribution of Parkin, PINK1 and DJ-1 genes to selective neuronal degeneration in Parkinson’s disease publication-title: Eur. J. Neurosci. contributor: fullname: Havekes – volume: 94 start-page: 335 year: 2018 ident: ref_118 article-title: Wilson disease: More than meets the eye publication-title: Postgrad. Med. J. doi: 10.1136/postgradmedj-2017-135381 contributor: fullname: Kelly – volume: 687 start-page: 88 year: 2018 ident: ref_152 article-title: Elevated microRNA-520d-5p in the serum of patients with Parkinson’s disease, possibly through regulation of ceruloplasmin expression publication-title: Neurosci. Lett. doi: 10.1016/j.neulet.2018.09.034 contributor: fullname: Jin – volume: 434 start-page: 212 year: 2005 ident: ref_210 article-title: Peptidylglycine-alpha-amidating monooxygenase activity and protein are lower in copper-deficient rats and suckling copper-deficient mice publication-title: Arch. Biochem. Biophys. doi: 10.1016/j.abb.2004.10.030 contributor: fullname: Prohaska – volume: 20 start-page: 1177 year: 2014 ident: ref_139 article-title: Serum microRNA-133b is associated with low ceruloplasmin levels in Parkinson’s disease publication-title: Park. Relat. Disord. doi: 10.1016/j.parkreldis.2014.08.016 contributor: fullname: Zhao – volume: 14 start-page: 103 year: 2015 ident: ref_217 article-title: Wilson’s disease and other neurological copper disorders publication-title: Lancet Neurol. doi: 10.1016/S1474-4422(14)70190-5 contributor: fullname: Bandmann – volume: 96 start-page: 100105 year: 2021 ident: ref_266 article-title: The essential elements of Alzheimer’s disease publication-title: J. Biol. Chem. doi: 10.1074/jbc.REV120.008207 contributor: fullname: Lei – ident: ref_143 doi: 10.3390/biom12050714 – volume: 34 start-page: 1 year: 2023 ident: ref_154 article-title: Missing heritability of Wilson disease: A search for the uncharacterized mutations publication-title: Mamm. Genome doi: 10.1007/s00335-022-09971-y contributor: fullname: Roy – volume: 91 start-page: 402 year: 2013 ident: ref_273 article-title: Serum copper, zinc and selenium levels in Tunisian patients with Parkinson’s disease publication-title: Tunis Med. contributor: fullname: Aissi – ident: ref_138 doi: 10.3390/jpm9030041 – volume: 5 start-page: 204 year: 2014 ident: ref_188 article-title: Ceruloplasmin-ferroportin system of iron traffic in vertebrates publication-title: World J. Biol. Chem. doi: 10.4331/wjbc.v5.i2.204 contributor: fullname: Musci – volume: 291 start-page: 220 year: 2002 ident: ref_100 article-title: Characterization of a cytochrome b(558) ferric/cupric reductase from rabbit duodenal brush border membranes. Biochem publication-title: Biophys. Res. Commun. doi: 10.1006/bbrc.2002.6423 contributor: fullname: Solioz – volume: 22 start-page: 102 year: 2022 ident: ref_261 article-title: Connecting copper and cancer: From transition metal signalling to metalloplasia publication-title: Nat. Rev. Cancer doi: 10.1038/s41568-021-00417-2 contributor: fullname: Ge – volume: 14 start-page: 797833 year: 2021 ident: ref_231 article-title: Mitochondrial function and Parkinson’s disease: From the perspective of the electron transport chain publication-title: Front. Mol. Neurosci. doi: 10.3389/fnmol.2021.797833 contributor: fullname: Li – volume: 40 start-page: 430 year: 2003 ident: ref_196 article-title: Clinical Investigations Standing Committee of the Association of Clinical Biochemists. Wilson’s disease: The importance of measuring serum caeruloplasmin non-immunologically publication-title: Ann. Clin. Biochem. doi: 10.1258/000456303763046021 contributor: fullname: Walshe – volume: 249 start-page: E77 year: 1985 ident: ref_245 article-title: Copper transport in rats involving a new plasma protein publication-title: Am. J. Physiol. contributor: fullname: Weiss – volume: 1012 start-page: 299 year: 2004 ident: ref_144 article-title: Aceruloplasminemia: An inherited neurodegenerative disease with impairment of iron homeostasis publication-title: Ann. N. Y. Acad. Sci. doi: 10.1196/annals.1306.024 contributor: fullname: Xu – volume: 134 start-page: 50 year: 2011 ident: ref_284 article-title: Decreased serum ceruloplasmin levels characteristically aggravate nigral iron deposition in Parkinson’s disease publication-title: Brain doi: 10.1093/brain/awq319 contributor: fullname: Jin – volume: 120 start-page: 1297 year: 2020 ident: ref_25 article-title: Genetics of Parkinson’s disease publication-title: Acta Neurol. Belg. doi: 10.1007/s13760-020-01473-5 contributor: fullname: Cherian – volume: 4 start-page: 176 year: 2013 ident: ref_63 article-title: Discovery of human zinc deficiency: Its impact on human health and disease publication-title: Adv. Nutr. doi: 10.3945/an.112.003210 contributor: fullname: Prasad – volume: 15 start-page: 695 year: 2022 ident: ref_181 article-title: Molecular functions of ceruloplasmin in metabolic disease pathology publication-title: Diabetes Metab. Syndr. Obes. doi: 10.2147/DMSO.S346648 contributor: fullname: Liu – volume: 284 start-page: 1873 year: 2009 ident: ref_148 article-title: Reactive oxygen species regulate ceruloplasmin by a novel mRNA decay mechanism involving its 3′-untranslated region: Implications in neurodegenerative diseases publication-title: J. Biol. Chem. doi: 10.1074/jbc.M804079200 contributor: fullname: Tapryal – volume: 23 start-page: 1509 year: 2003 ident: ref_147 article-title: Transcript-selective translational silencing by gamma interferon is directed by a novel structural element in the ceruloplasmin mRNA 3′ untranslated region publication-title: Mol. Cell. Biol. doi: 10.1128/MCB.23.5.1509-1519.2003 contributor: fullname: Sampath – volume: 329 start-page: 1663 year: 2010 ident: ref_43 article-title: Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro publication-title: Science doi: 10.1126/science.1195227 contributor: fullname: Burre – volume: 109 start-page: 4760 year: 2009 ident: ref_92 article-title: Structural biology of copper trafficking publication-title: Chem. Rev. doi: 10.1021/cr900104z contributor: fullname: Boal – volume: 73 start-page: 554 year: 2013 ident: ref_220 article-title: Ceruloplasmin dysfunction and therapeutic potential for Parkinson disease publication-title: Ann. Neurol. doi: 10.1002/ana.23817 contributor: fullname: Ayton – volume: 42 start-page: 675 year: 2017 ident: ref_283 article-title: Serum ceruloplasmin and striatal dopamine transporter density in Parkinson disease: Comparison with 123I-FP-CIT spect publication-title: Clin. Nucl. Med. doi: 10.1097/RLU.0000000000001734 contributor: fullname: Song – volume: 24 start-page: 55 year: 2018 ident: ref_39 article-title: Competition between abiogenic Al3+ and native Mg2+, Fe2+ and Zn2+ ions in protein binding sites: Implications for aluminum toxicity publication-title: J. Mol. Model. doi: 10.1007/s00894-018-3592-0 contributor: fullname: Dudev – volume: 24 start-page: 234 year: 2021 ident: ref_290 article-title: Evidence-Based Discriminant Analysis: A New Insight into Iron Profile for the Diagnosis of Parkinson’s Disease publication-title: Ann.Indian Acad. Neurol. doi: 10.4103/aian.AIAN_419_20 contributor: fullname: Tripathi – ident: ref_12 doi: 10.3390/ijerph13090881 – volume: 26 start-page: 80 year: 2019 ident: ref_178 article-title: Pathophysiology and classification of iron overload diseases; update 2018 publication-title: Transfus. Clin. Biol. doi: 10.1016/j.tracli.2018.08.006 contributor: fullname: Brissot – volume: 62 start-page: 1484 year: 2023 ident: ref_269 article-title: Biochemical characterization of Caenorhabditis elegans ferritins publication-title: Biochemistry doi: 10.1021/acs.biochem.3c00005 contributor: fullname: Mubarak – volume: 33 start-page: 527 year: 2013 ident: ref_79 article-title: The effect of zinc and the role of p53 in copper-induced cellular stress responses publication-title: J. Appl. Toxicol. doi: 10.1002/jat.2854 contributor: fullname: Formigari – volume: 134 start-page: jcs240523 year: 2021 ident: ref_57 article-title: Dynamic and cell-specific transport networks for intracellular copper ions publication-title: J. Cell Sci. doi: 10.1242/jcs.240523 contributor: fullname: Lutsenko – volume: 126 start-page: 354 year: 2016 ident: ref_280 article-title: Association between sex, systemic iron variation and probability of Parkinson’s disease publication-title: Int. J. Neurosci. doi: 10.3109/00207454.2015.1020113 contributor: fullname: Mariani – volume: 3 start-page: 14 year: 1993 ident: ref_256 article-title: Isolation of a candidate gene for Menkes disease that encodes a potential heavy metal binding protein publication-title: Nat. Genet. doi: 10.1038/ng0193-14 contributor: fullname: Chelly – volume: 281 start-page: 341 year: 1999 ident: ref_33 article-title: Parkinson disease in twins: 476 an etiologic study publication-title: JAMA doi: 10.1001/jama.281.4.341 contributor: fullname: Tanner – volume: 6 start-page: 1970 year: 2014 ident: ref_208 article-title: The effects of silver ions on copper metabolism in rats publication-title: Metallomics doi: 10.1039/C4MT00107A contributor: fullname: Ilyechova – volume: 499 start-page: 329 year: 1977 ident: ref_246 article-title: Plasma ceruloplasmin. Evidence for its presence in and uptake by heart and other organs of the rat publication-title: Biochim. Biophys. Acta doi: 10.1016/0304-4165(77)90064-2 contributor: fullname: Linder – volume: 401 start-page: 1 year: 2019 ident: ref_47 article-title: Contributions of VPS35 Mutations to Parkinson’s Disease publication-title: Neuroscience doi: 10.1016/j.neuroscience.2019.01.006 contributor: fullname: Rahman – volume: 380 start-page: 240 year: 2004 ident: ref_249 article-title: Regional distribution of manganese, iron, copper, and zinc in the rat brain during development publication-title: Anal. Bioanal. Chem. doi: 10.1007/s00216-004-2697-8 contributor: fullname: Tarohda – volume: 51 start-page: 14 year: 2021 ident: ref_103 article-title: Kinetics of Cu(II) complexation by ATCUN/NTS and related peptides: A gold mine of novel ideas for copper biology publication-title: Dalton Trans. doi: 10.1039/D1DT02878B contributor: fullname: Kotuniak – volume: 4 start-page: 75 year: 2015 ident: ref_95 article-title: A review on role of essential trace elements in health and disease publication-title: J. Dr. NTR Univ. Health Sci. doi: 10.4103/2277-8632.158577 contributor: fullname: Prashanth – volume: 109 start-page: 1979 year: 1979 ident: ref_226 article-title: A conspectus of research on copper metabolism and requirements of man publication-title: J. Nutr. doi: 10.1093/jn/109.11.1979 contributor: fullname: Mason – ident: ref_202 doi: 10.3390/biom11070960 – volume: 17 start-page: 432 year: 2018 ident: ref_176 article-title: Ceruloplasmin and hephaestin jointly protect the exocrine pancreas against oxidative damage by facilitating iron efflux publication-title: Redox Biol. doi: 10.1016/j.redox.2018.05.013 contributor: fullname: Chen – ident: ref_182 doi: 10.20944/preprints201809.0161.v1 – volume: 15 start-page: 177 year: 2010 ident: ref_37 article-title: A thallium transport FLIPR-based assay for the identification of KCC2-positive modulators publication-title: J. Biomol. Screen. doi: 10.1177/1087057109355708 contributor: fullname: Zhang – volume: 17 start-page: 745 year: 2016 ident: ref_222 article-title: Integrins in synapse regulation publication-title: Nat. Rev. Neurosci. doi: 10.1038/nrn.2016.138 contributor: fullname: Park – volume: 36 start-page: 263 year: 2023 ident: ref_119 article-title: The biology of mammalian multi-copper ferroxidases publication-title: Biometals doi: 10.1007/s10534-022-00370-z contributor: fullname: Helman – volume: 39 start-page: 59 year: 2006 ident: ref_149 article-title: Translational control of ceruloplasmin gene expression: Beyond the IRE publication-title: Biol. Res. doi: 10.4067/S0716-97602006000100007 contributor: fullname: Mazumder – volume: 738 start-page: 265 year: 1996 ident: ref_215 article-title: Increased regional brain concentrations of ceruloplasmin in neurodegenerative disorders publication-title: Brain Res. doi: 10.1016/S0006-8993(96)00782-2 contributor: fullname: Loeffler – volume: 5 start-page: 14 year: 2017 ident: ref_21 article-title: Epidemiology of Parkinson’s disease-east versus west publication-title: Mov. Disord. Clin. Pract. doi: 10.1002/mdc3.12568 contributor: fullname: Abbas – volume: 108 start-page: 140 year: 2002 ident: ref_239 article-title: Mutations in the dopamine beta-hydroxylase gene are associated with human norepinephrine deficiency publication-title: Am. J. Med. Genet. doi: 10.1002/ajmg.10196 contributor: fullname: Kim – volume: 31 start-page: R421 year: 2021 ident: ref_76 article-title: Copper biology publication-title: Curr. Biol. doi: 10.1016/j.cub.2021.03.054 contributor: fullname: Tsang – ident: ref_116 doi: 10.3390/ijms21155536 – volume: 80 start-page: 630 year: 2020 ident: ref_195 article-title: Assay in serum of exchangeable copper and total copper using inductively coupled plasma mass spectrometry (ICP-MS): Development, optimisation and evaluation of a routine procedure publication-title: Scand. J. Clin. Lab. Investig. doi: 10.1080/00365513.2020.1821397 contributor: fullname: Daymond – volume: 7 start-page: 10640 year: 2016 ident: ref_254 article-title: Neuronal differentiation is associated with a redox-regulated increase of copper flow to the secretory pathway publication-title: Nat. Commun. doi: 10.1038/ncomms10640 contributor: fullname: Hatori – volume: 18 start-page: 299 year: 2019 ident: ref_235 article-title: Superoxide dismutase coding of gene polymorphisms associated with susceptibility to Parkinson’s disease publication-title: J. Integr. Neurosci. doi: 10.31083/j.jin.2019.03.127 contributor: fullname: Liu – volume: 370 start-page: 673 year: 1989 ident: ref_105 article-title: A redetermination of the concentration of alpha 2-macroglobulin in human plasma publication-title: Biol. Chem. Hoppe Seyler doi: 10.1515/bchm3.1989.370.2.673 contributor: fullname: Coan – volume: 18 start-page: 533 year: 2021 ident: ref_199 article-title: Non-ceruloplasmin copper as a stratification biomarker of Alzheimer’s disease patients: How to measure and use it publication-title: Curr. Alzheimer Res. doi: 10.2174/1567205018666211022085755 contributor: fullname: Squitti – volume: 54 start-page: 7096 year: 2017 ident: ref_13 article-title: Relationship between obesity, Alzheimer’s disease, and Parkinson’s disease: An astrocentric View publication-title: Mol. Neurobiol. doi: 10.1007/s12035-016-0193-8 contributor: fullname: Echeverria – volume: 46 start-page: 279 year: 2012 ident: ref_141 article-title: MicroRNAs in Parkinson’s disease publication-title: Neurobiol. Dis. doi: 10.1016/j.nbd.2011.12.046 contributor: fullname: Mouradian – volume: 14 start-page: mfac039 year: 2022 ident: ref_40 article-title: Nanomolar affinity of EF-hands in neuronal calcium sensor 1 for bivalent cations Pb2+, Mn2+, and Hg2 publication-title: Metallomics doi: 10.1093/mtomcs/mfac039 contributor: fullname: Alam – volume: 13 start-page: 122 year: 2007 ident: ref_134 article-title: Three sisters with very-late-onset major depression and parkinsonism publication-title: Park. Relat. Disord. doi: 10.1016/j.parkreldis.2006.03.009 contributor: fullname: Sechi – volume: 54 start-page: 265 year: 2020 ident: ref_183 article-title: Moonlighting Proteins publication-title: Annu. Rev. Genet. doi: 10.1146/annurev-genet-030620-102906 contributor: fullname: Singh – volume: 66 start-page: 123 year: 2011 ident: ref_286 article-title: Reduced serum caeruloplasmin levels in non-wilsonian movement disorders publication-title: Eur. Neurol. doi: 10.1159/000330538 contributor: fullname: Ling – ident: ref_56 doi: 10.3390/ijms22094591 – volume: 14 start-page: 888942 year: 2022 ident: ref_30 article-title: Polymorphisms of Cytochromes P450 and Glutathione S-Transferases Synergistically Modulate Risk for Parkinson’s Disease publication-title: Front. Aging Neurosci. doi: 10.3389/fnagi.2022.888942 contributor: fullname: Fan – ident: ref_6 doi: 10.20944/preprints202203.0274.v1 – volume: 10 start-page: 15507 year: 2020 ident: ref_219 article-title: Ceruloplasmin oxidized and deamidated by Parkinson’s disease cerebrospinal fluid induces epithelial cells proliferation arrest and apoptosis publication-title: Sci. Rep. doi: 10.1038/s41598-020-72447-z contributor: fullname: Barbariga – volume: 13 start-page: e13275 year: 2021 ident: ref_5 article-title: Spectrum of non-motor symptoms in Parkinson’s disease publication-title: Cureus contributor: fullname: Kumaresan – volume: 3 start-page: 7 year: 1993 ident: ref_257 article-title: Isolation of a candidate gene for Menkes disease and evidence that it encodes a copper-transporting ATPase publication-title: Nat. Genet. doi: 10.1038/ng0193-7 contributor: fullname: Vulpe – volume: 289 start-page: 13726 year: 2014 ident: ref_236 article-title: Reaction mechanism of the bicopper enzyme peptidylglycine α-hydroxylating monooxygenase publication-title: J. Biol. Chem. doi: 10.1074/jbc.M114.558494 contributor: fullname: Abad – volume: 2020 start-page: 4293071 year: 2020 ident: ref_19 article-title: What and how can physical activity prevention function on Parkinson’s disease? publication-title: Oxid. Med. Cell. Longev. doi: 10.1155/2020/4293071 contributor: fullname: Fan – volume: 85 start-page: 779 year: 2015 ident: ref_230 article-title: Review of Amyotrophic Lateral Sclerosis, Parkinson’s and Alzheimer’s diseases helps further define pathology of the novel paradigm for Alzheimer’s with heavy metals as primary disease cause publication-title: Med. Hypotheses doi: 10.1016/j.mehy.2015.10.009 contributor: fullname: Cavaleri – volume: 115 start-page: 39 year: 1981 ident: ref_169 article-title: Intracellular distribution of rat-liver polyribosomes synthesizing coeruloplasmin publication-title: Eur. J. Biochem. doi: 10.1111/j.1432-1033.1981.tb06194.x contributor: fullname: Gaitskhoki – volume: 1248 start-page: 14 year: 2009 ident: ref_247 article-title: Copper transport to the brain by the blood-brain barrier and blood-CSF barrier publication-title: Brain Res. doi: 10.1016/j.brainres.2008.10.056 contributor: fullname: Choi – volume: 11 start-page: 165 year: 2002 ident: ref_155 article-title: Identification of a new copper metabolism gene by positional cloning in a purebred dog population publication-title: Hum. Mol. Genet. doi: 10.1093/hmg/11.2.165 contributor: fullname: Rothuizen – volume: 55 start-page: 117 year: 2018 ident: ref_279 article-title: Association of metals with the risk and clinical characteristics of Parkinson’s disease publication-title: Park. Relat. Disord. doi: 10.1016/j.parkreldis.2018.05.022 contributor: fullname: Kim – volume: 43 start-page: 517 year: 2018 ident: ref_55 article-title: Zinc Transporter Proteins publication-title: Neurochem. Res. doi: 10.1007/s11064-017-2454-y contributor: fullname: Baltaci – volume: 9 start-page: 501 year: 2019 ident: ref_17 article-title: Parkinson’s Disease in women and men: What’s the difference? publication-title: J. Park. Dis. contributor: fullname: Cerri – volume: 25 start-page: 2198 year: 2018 ident: ref_35 article-title: Metals and Parkinson’s Disease: Mechanisms and Biochemical Processes publication-title: Curr. Med. Chem. doi: 10.2174/0929867325666171129124616 contributor: fullname: Bjorklund – volume: 375 start-page: 1254 year: 2022 ident: ref_88 article-title: Copper induces cell death by targeting lipoylated TCA cycle proteins publication-title: Science doi: 10.1126/science.abf0529 contributor: fullname: Tsvetkov – volume: 397 start-page: 254 year: 2004 ident: ref_166 article-title: Expression of ceruloplasmin pseudogene in cultured human cells publication-title: Dokl. Biochem. Biophys. doi: 10.1023/B:DOBI.0000039476.31868.bc contributor: fullname: Vasin – volume: 300 start-page: C588 year: 2011 ident: ref_96 article-title: Acquisition of dietary copper: A role for anion transporters in intestinal apical copper uptake publication-title: Am. J. Physiol. Cell Physiol. doi: 10.1152/ajpcell.00054.2010 contributor: fullname: Zimnicka – volume: 18 start-page: 35 year: 2017 ident: ref_64 article-title: Inherited Disorders of Manganese Metabolism publication-title: Adv. Neurobiol. doi: 10.1007/978-3-319-60189-2_3 contributor: fullname: Zogzas – volume: 21 start-page: 6440 year: 2001 ident: ref_150 article-title: Translational silencing of ceruloplasmin requires the essential elements of mRNA circularization: Poly(A) tail, poly(A)-binding protein, and eukaryotic translation initiation factor 4G publication-title: Mol. Cell. Biol. doi: 10.1128/MCB.21.19.6440-6449.2001 contributor: fullname: Mazumder – volume: 472 start-page: 1415 year: 2020 ident: ref_94 article-title: The molecular mechanisms of copper metabolism and its roles in human diseases publication-title: Pflugers Arch. doi: 10.1007/s00424-020-02412-2 contributor: fullname: Chen – volume: 112 start-page: 30 year: 1992 ident: ref_282 article-title: Serum levels of zinc and copper in patients with Parkinson’s disease publication-title: J. Neurol. Sci. doi: 10.1016/0022-510X(92)90127-7 contributor: fullname: Herrero – volume: 135 start-page: 54 year: 2018 ident: ref_131 article-title: A low blood copper concentration is a co-morbidity burden factor in Parkinson’s disease development publication-title: Neurosci. Res. doi: 10.1016/j.neures.2017.11.011 contributor: fullname: Ilyechova – volume: 158 start-page: 105474 year: 2021 ident: ref_224 article-title: Oxidized/deamidated-ceruloplasmin dysregulates choroid plexus epithelial cells functionality and barrier properties via RGD-recognizing integrin binding publication-title: Neurobiol. Dis. doi: 10.1016/j.nbd.2021.105474 contributor: fullname: Zanardi – volume: 36 start-page: 33 year: 2017 ident: ref_142 article-title: New insights in the neurological phenotype of aceruloplasminemia in Caucasian patients publication-title: Park. Relat. Disord. doi: 10.1016/j.parkreldis.2016.12.010 contributor: fullname: Vroegindeweij – volume: 30 start-page: 31 year: 1999 ident: ref_250 article-title: A comparative study of the transport dynamics of the peptide moiety of the milk ceruloplasmin molecule in the body of rats with embryonic and adult types of copper metabolism publication-title: Ontogenez contributor: fullname: Puchkova – volume: 8 start-page: 515 year: 2012 ident: ref_130 article-title: Ceruloplasmin and iron in Alzheimer’s disease and Parkinson’s disease: A synopsis of recent studies publication-title: Neuropsychiatr. Dis. Treat. contributor: fullname: Kristinsson – volume: 1 start-page: 54 year: 2007 ident: ref_189 article-title: Docking study on mammalian CTR1 copper importer motifs publication-title: BMC Syst. Biol. doi: 10.1186/1752-0509-1-S1-P54 contributor: fullname: Zatulovskiy – volume: 142 start-page: 19 year: 2017 ident: ref_264 article-title: The genetics of Wilson disease publication-title: Handb. Clin. Neurol. doi: 10.1016/B978-0-444-63625-6.00003-3 contributor: fullname: Chang – volume: 397 start-page: 2284 year: 2021 ident: ref_14 article-title: Parkinson’s disease publication-title: Lancet doi: 10.1016/S0140-6736(21)00218-X contributor: fullname: Bloem – volume: 31 start-page: 178 year: 2015 ident: ref_110 article-title: The role of Ctr1 and Ctr2 in mammalian copper homeostasis and platinum-based chemotherapy publication-title: J. Trace Elem. Med. Biol. doi: 10.1016/j.jtemb.2014.03.006 contributor: fullname: Thiele – volume: 30 start-page: 1063 year: 1998 ident: ref_129 article-title: ATP7B (WND) protein publication-title: Int. J. Biochem. Cell Biol. doi: 10.1016/S1357-2725(98)00073-9 contributor: fullname: Terada – volume: 4 start-page: 21 year: 2018 ident: ref_117 article-title: Wilson disease publication-title: Nat. Rev. Dis. Primers doi: 10.1038/s41572-018-0018-3 contributor: fullname: Litwin – volume: 40 start-page: 357 year: 2020 ident: ref_272 article-title: PARK2 and PARK7 Gene Polymorphisms as Risk Factors Associated with Serum Element Concentrations and Clinical Symptoms of Parkinson’s Disease publication-title: Cell. Mol. Neurobiol. doi: 10.1007/s10571-019-00734-z contributor: fullname: Sanyal – volume: 2 start-page: a009258 year: 2012 ident: ref_2 article-title: Parkinson’s disease and parkinsonism: Neuropathology publication-title: Cold Spring Harb. Perspect. Med. doi: 10.1101/cshperspect.a009258 contributor: fullname: Dickson – ident: ref_69 doi: 10.3390/ijms21239259 – volume: 180 start-page: 266 year: 2019 ident: ref_145 article-title: Clinical relevance of heterozygosis for aceruloplasminemia publication-title: Am. J. Med. Genet. B Neuropsychiatr. Genet. doi: 10.1002/ajmg.b.32723 contributor: fullname: Borges – volume: 37 start-page: 1207 year: 2012 ident: ref_151 article-title: Altered microRNAs expression profiling in experimental silicosis rats publication-title: J. Toxicol. Sci. doi: 10.2131/jts.37.1207 contributor: fullname: Faxuan – volume: 46 start-page: 3307 year: 2019 ident: ref_156 article-title: In-silico analysis of novel p.(Gly14Ser) variant of ATOX1 gene: Plausible role in modulating ATOX1-ATP7B interaction publication-title: Mol. Biol. Rep. doi: 10.1007/s11033-019-04791-x contributor: fullname: Kumari – volume: 261 start-page: 259 year: 2014 ident: ref_22 article-title: Recent advances in Parkinson’s disease genetics publication-title: J. Neurol. doi: 10.1007/s00415-013-7003-2 contributor: fullname: Lubbe – volume: 221 start-page: 111478 year: 2021 ident: ref_203 article-title: A luminescent ATCUN peptide variant with enhanced properties for copper(II) sensing in biological media publication-title: J. Inorg. Biochem. doi: 10.1016/j.jinorgbio.2021.111478 contributor: fullname: Falcone – volume: 6 start-page: 89 year: 2014 ident: ref_268 article-title: Caenorhabditis elegans: A model to investigate oxidative stress and metal dyshomeostasis in Parkinson’s disease publication-title: Front. Aging Neurosci. doi: 10.3389/fnagi.2014.00089 contributor: fullname: Chege – volume: 41 start-page: 1233 year: 2009 ident: ref_77 article-title: ATOX1: A novel copper-responsive transcription factor in mammals? publication-title: Int. J. Biochem. Cell Biol. doi: 10.1016/j.biocel.2008.08.001 contributor: fullname: Muller – ident: ref_126 doi: 10.1371/journal.pone.0149516 – volume: 30 start-page: 823 year: 2017 ident: ref_115 article-title: The six metal binding domains in human copper transporter, ATP7B: Molecular biophysics and disease-causing mutations publication-title: Biometals doi: 10.1007/s10534-017-0058-2 contributor: fullname: Li – ident: ref_204 doi: 10.3390/ijms24076377 – volume: 8 start-page: 1433 year: 2018 ident: ref_68 article-title: Intersection of Iron and Copper Metabolism in the Mammalian Intestine and Liver publication-title: Compr. Physiol. doi: 10.1002/cphy.c170045 contributor: fullname: Doguer – volume: 284 start-page: 805 year: 1999 ident: ref_93 article-title: Undetectable intracellular free copper: The requirement of a copper chaperone for superoxide dismutase publication-title: Science doi: 10.1126/science.284.5415.805 contributor: fullname: Rae – volume: 9 start-page: 612476 year: 2021 ident: ref_27 article-title: PARK Genes link mitochondrial dysfunction and alpha-synuclein pathology in sporadic Parkinson’s disease publication-title: Front. Cell. Dev. Biol. doi: 10.3389/fcell.2021.612476 contributor: fullname: Li – volume: 21 start-page: 195 year: 1999 ident: ref_174 article-title: Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse publication-title: Nat. Genet. doi: 10.1038/5979 contributor: fullname: Vulpe – volume: 26 start-page: 612 year: 2021 ident: ref_80 article-title: High-dose copper activates p53-independent apoptosis through the induction of nucleolar stress in human cell lines publication-title: Apoptosis doi: 10.1007/s10495-021-01692-y contributor: fullname: Chen – volume: 14 start-page: mfac006 year: 2022 ident: ref_207 article-title: Secretion and uptake of copper via a small copper carrier in blood fluid publication-title: Metallomics doi: 10.1093/mtomcs/mfac006 contributor: fullname: Gioilli – volume: 31 start-page: 4121 year: 2022 ident: ref_157 article-title: Newly identified disorder of copper metabolism caused by variants in CTR1, a high-affinity copper transporter publication-title: Hum. Mol. Genet. doi: 10.1093/hmg/ddac156 contributor: fullname: Batzios – volume: 143 start-page: 360 year: 2006 ident: ref_212 article-title: Plasma peptidylglycine alpha-amidating monooxygenase (PAM) and ceruloplasmin are affected by age and copper status in rats and mice publication-title: Comp. Biochem. Physiol. B Biochem. Mol. Biol. doi: 10.1016/j.cbpb.2005.12.010 contributor: fullname: Prohaska – volume: 107 start-page: 129 year: 2012 ident: ref_91 article-title: Coordination chemistry of copper proteins: How nature handles a toxic cargo for essential function publication-title: J. Inorg. Biochem. doi: 10.1016/j.jinorgbio.2011.11.024 contributor: fullname: Rubino – volume: 6 start-page: 49 year: 2016 ident: ref_70 article-title: Copper containing enzymes: Site types and low-molecular-weight model compounds publication-title: Rev. J. Chem. doi: 10.1134/S2079978016010027 contributor: fullname: Tishchenko – volume: 123 start-page: 261 year: 2008 ident: ref_198 article-title: Ceruloplasmin, an indicator of copper status publication-title: Biol. Trace Elem. Res. doi: 10.1007/s12011-008-8110-2 contributor: fullname: Arredondo – volume: 1868 start-page: 118867 year: 2021 ident: ref_112 article-title: Getting out what you put in: Copper in mitochondria and its impacts on human disease publication-title: Biochim. Biophys. Acta Mol. Cell Res. doi: 10.1016/j.bbamcr.2020.118867 contributor: fullname: Cobine – volume: 22 start-page: 439 year: 2002 ident: ref_120 article-title: Ceruloplasmin metabolism and function publication-title: Annu. Rev. Nutr. doi: 10.1146/annurev.nutr.22.012502.114457 contributor: fullname: Hellman – volume: 2014 start-page: 147251 year: 2014 ident: ref_67 article-title: Copper and copper proteins in Parkinson’s disease publication-title: Oxid. Med. Cell. Longev. doi: 10.1155/2014/147251 contributor: fullname: Montes – volume: 105 start-page: 419 year: 2012 ident: ref_192 article-title: Serum ‘free’ copper in Wilson disease publication-title: QJM doi: 10.1093/qjmed/hcr229 contributor: fullname: Walshe – volume: 33 start-page: 309 year: 2016 ident: ref_170 article-title: Human plasma protein N-glycosylation publication-title: Glycoconj. J. doi: 10.1007/s10719-015-9626-2 contributor: fullname: Clerc – volume: 14 start-page: 105 year: 2023 ident: ref_262 article-title: Copper homeostasis and copper-induced cell death in the pathogenesis of cardiovascular disease and therapeutic strategies publication-title: Cell Death Dis. doi: 10.1038/s41419-023-05639-w contributor: fullname: Chen – volume: 17 start-page: 523 year: 2022 ident: ref_16 article-title: Diabetes mellitus and Parkinson’s disease: Dangerous liaisons between insulin and dopamine publication-title: Neural Regen. Res. doi: 10.4103/1673-5374.320965 contributor: fullname: Montinaro – volume: 196 start-page: 101890 year: 2021 ident: ref_66 article-title: Ferroptosis and its potential role in the physiopathology of Parkinson’s Disease publication-title: Prog. Neurobiol. doi: 10.1016/j.pneurobio.2020.101890 contributor: fullname: Bouchaoui – volume: 1840 start-page: 1771 year: 2014 ident: ref_187 article-title: Iron uptake and transfer from ceruloplasmin to transferrin publication-title: Biochim. Biophys. Acta doi: 10.1016/j.bbagen.2014.01.011 contributor: fullname: Eid – volume: 42 start-page: 640 year: 2021 ident: ref_62 article-title: Iron metabolism: Pathophysiology and pharmacology publication-title: Trends Pharmacol. Sci. doi: 10.1016/j.tips.2021.05.001 contributor: fullname: Roemhild – volume: 9 start-page: 1169 year: 2017 ident: ref_81 article-title: Copper-finger protein of Sp1: The molecular basis of copper sensing publication-title: Metallomics doi: 10.1039/C7MT00184C contributor: fullname: Yuan – volume: 103 start-page: 585 year: 2023 ident: ref_158 article-title: Fatal congenital copper transport defect caused by a homozygous likely pathogenic variant of SLC31A1 publication-title: Clin. Genet. doi: 10.1111/cge.14289 contributor: fullname: Dame – volume: 131 start-page: 160 year: 2009 ident: ref_191 article-title: Direct measurement of free copper in serum or plasma ultrafiltrate publication-title: Am. J. Clin. Pathol. doi: 10.1309/AJCP7Z9KBFINVGYF contributor: fullname: McMillin – volume: 18 start-page: 435 year: 2017 ident: ref_4 article-title: Non-motor features of Parkinson disease publication-title: Nat. Rev. Neurosci. doi: 10.1038/nrn.2017.62 contributor: fullname: Schapira – volume: 231 start-page: 1459 year: 2006 ident: ref_99 article-title: Metallothionein redox cycle and function publication-title: Exp. Biol. Med. doi: 10.1177/153537020623100903 contributor: fullname: Kang – volume: 69 start-page: 1904 year: 1997 ident: ref_108 article-title: Alpha2-macroglobulin complexes with and mediates the endocytosis of beta-amyloid peptide via cell surface low-density lipoprotein receptor-related protein publication-title: J. Neurochem. doi: 10.1046/j.1471-4159.1997.69051904.x contributor: fullname: Narita – volume: 54 start-page: 147 year: 1998 ident: ref_164 article-title: Ran-2, a glial lineage marker, is a GPI-anchored form of ceruloplasmin publication-title: J. Neurosci. Res. doi: 10.1002/(SICI)1097-4547(19981015)54:2<147::AID-JNR3>3.0.CO;2-E contributor: fullname: Salzer – volume: 60 start-page: 25346 year: 2021 ident: ref_114 article-title: APEX2-based proximity labeling of Atox1 identifies CRIP2 as a nuclear copper-binding protein that regulates autophagy activation publication-title: Angew. Chem. Int. Ed. Engl. doi: 10.1002/anie.202108961 contributor: fullname: Chen – volume: 41 start-page: 487 year: 2016 ident: ref_83 article-title: Copper transporters and chaperones: Their function on angiogenesis and cellular signalling publication-title: J. Biosci. doi: 10.1007/s12038-016-9629-6 contributor: fullname: Dhivya – volume: 62 start-page: 2050 year: 2005 ident: ref_173 article-title: Function and molecular evolution of multicopper blue proteins publication-title: Cell. Mol. Life Sci. doi: 10.1007/s00018-004-5076-x contributor: fullname: Nakamura – volume: 77 start-page: 2157 year: 2020 ident: ref_85 article-title: Copper-mediated thiol potentiation and mutagenesis-guided modeling suggest a highly conserved copper-binding motif in human OR2M3 publication-title: Cell. Mol. Life Sci. doi: 10.1007/s00018-019-03279-y contributor: fullname: Haag – volume: 8 start-page: 607 year: 2021 ident: ref_10 article-title: Metal elements and pesticides as risk factors for Parkinson’s disease—A review publication-title: Toxicol. Rep. doi: 10.1016/j.toxrep.2021.03.009 contributor: fullname: Ullah – volume: 293 start-page: 4628 year: 2018 ident: ref_75 article-title: Copper signaling in the brain and beyond publication-title: J. Biol. Chem. doi: 10.1074/jbc.R117.000176 contributor: fullname: Ackerman – volume: 85 start-page: 600 year: 2019 ident: ref_34 article-title: Concordance for Parkinson’s disease in twins: A 20-year update publication-title: Ann. Neurol. doi: 10.1002/ana.25441 contributor: fullname: Goldman – volume: 62 start-page: 4021 year: 2023 ident: ref_97 article-title: Exploration of the potential role of serum albumin in the delivery of Cu(I) to Ctr1 publication-title: Inorg. Chem. doi: 10.1021/acs.inorgchem.2c03753 contributor: fullname: Schulte – volume: 10 start-page: 973 year: 2019 ident: ref_214 article-title: Brain tyrosinase overexpression implicates age-dependent neuromelanin production in Parkinson’s disease pathogenesis publication-title: Nat. Commun. doi: 10.1038/s41467-019-08858-y contributor: fullname: Laguna – volume: 280 start-page: 9640 year: 2005 ident: ref_251 article-title: The copper-transporting ATPases, Menkes and Wilson disease proteins, have distinct roles in adult and developing cerebellum publication-title: J. Biol. Chem. doi: 10.1074/jbc.M413840200 contributor: fullname: Barnes – volume: 8 start-page: 711227 year: 2021 ident: ref_74 article-title: Role of Copper on Mitochondrial Function and Metabolism publication-title: Front. Mol. Biosci. doi: 10.3389/fmolb.2021.711227 contributor: fullname: Ruiz – volume: 736 start-page: 135297 year: 2020 ident: ref_276 article-title: Dysregulation of body antioxidant content is related to initiation and progression of Parkinson’s disease publication-title: Neurosci. Lett. doi: 10.1016/j.neulet.2020.135297 contributor: fullname: Fattah – volume: 2 start-page: 141 year: 2005 ident: ref_122 article-title: [In vivo expression of copper transporting proteins in rat brain sections] publication-title: Izv. Akad. Nauk. Ser. Biol. contributor: fullname: Platonova – volume: 4 start-page: 579 year: 1999 ident: ref_171 article-title: An X-ray crystallographic study of the binding sites of the azide inhibitor and organic substrates to ceruloplasmin, a multi-copper oxidase in the plasma publication-title: J. Biol. Inorg. Chem. doi: 10.1007/s007750050380 contributor: fullname: Zaitsev – volume: 77 start-page: 3208 year: 2005 ident: ref_243 article-title: Imaging of copper, zinc, and other elements in thin section of human brain samples (hippocampus) by laser ablation inductively coupled plasma mass spectrometry publication-title: Anal. Chem. doi: 10.1021/ac040184q contributor: fullname: Becker – ident: ref_225 doi: 10.3390/ijms22020663 – volume: 1823 start-page: 1594 year: 2012 ident: ref_146 article-title: Role of metal in folding and stability of copper proteins in vitro publication-title: Biochim. Biophys. Acta doi: 10.1016/j.bbamcr.2012.01.013 contributor: fullname: Niemiec – volume: 31 start-page: 13301 year: 2011 ident: ref_185 article-title: Iron efflux from oligodendrocytes is differentially regulated in gray and white matter publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.2838-11.2011 contributor: fullname: Schulz – volume: 3 start-page: 1647 year: 1994 ident: ref_260 article-title: Characterization of the Wilson disease gene encoding a P-type copper transporting ATPase: Genomic organization, alternative splicing, and structure/function predictions publication-title: Hum. Mol. Genet. doi: 10.1093/hmg/3.9.1647 contributor: fullname: Petrukhin – volume: 140 start-page: 1728 year: 2010 ident: ref_175 article-title: Identification of zyklopen, a new member of the vertebrate multicopper ferroxidase family, and characterization in rodents and human cells publication-title: J. Nutr. doi: 10.3945/jn.109.117531 contributor: fullname: Chen – ident: ref_137 doi: 10.3390/genes13122361 – volume: 16 start-page: 394 year: 2013 ident: ref_45 article-title: Interplay of LRRK2 with chaperone-mediated autophagy publication-title: Nat. Neurosci. doi: 10.1038/nn.3350 contributor: fullname: Orenstein – volume: 61 start-page: 1042 year: 1999 ident: ref_163 article-title: Glycosyl phosphatidylinositol-anchored ceruloplasmin is expressed by rat Sertoli cells and is concentrated in detergent-insoluble membrane fractions publication-title: Biol. Reprod. doi: 10.1095/biolreprod61.4.1042 contributor: fullname: Fortna – volume: 17 start-page: 66 year: 2017 ident: ref_24 article-title: new genes causing hereditary Parkinson’s disease or parkinsonism publication-title: Curr. Neurol. Neurosci. Rep. doi: 10.1007/s11910-017-0780-8 contributor: fullname: Puschmann – volume: 111 start-page: 567 year: 2006 ident: ref_89 article-title: Zinc and copper: Pharmacological probes and endogenous modulators of neuronal excitability publication-title: Pharmacol. Ther. doi: 10.1016/j.pharmthera.2005.11.004 contributor: fullname: Mathie – volume: 36 start-page: 1 year: 2020 ident: ref_1 article-title: Parkinson disease epidemiology, pathology, genetics, and pathophysiology publication-title: Clin. Geriatr. Med. doi: 10.1016/j.cger.2019.08.002 contributor: fullname: Simon – volume: 17 start-page: 1187 year: 2012 ident: ref_177 article-title: Functional role of the putative iron ligands in the ferroxidase activity of recombinant human hephaestin publication-title: J. Biol. Inorg. Chem. doi: 10.1007/s00775-012-0932-x contributor: fullname: Vashchenko – volume: 63 start-page: 1427 year: 2018 ident: ref_201 article-title: Serum copper is not altered in frontotemporal lobar degeneration publication-title: J. Alzheimers Dis. doi: 10.3233/JAD-171074 contributor: fullname: Squitti – volume: 5 start-page: 327 year: 1993 ident: ref_259 article-title: The Wilson disease gene is a putative copper transporting P-type ATPase similar to the Menkes gene publication-title: Nat. Genet. doi: 10.1038/ng1293-327 contributor: fullname: Bull – volume: 31 start-page: 763 year: 2010 ident: ref_23 article-title: Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: A mutation update publication-title: Hum. Mutat. doi: 10.1002/humu.21277 contributor: fullname: Nuytemans – ident: ref_267 doi: 10.3390/biom10020195 – volume: 220 start-page: e202012095 year: 2021 ident: ref_28 article-title: The cell biology of Parkinson’s disease publication-title: J. Cell Biol. doi: 10.1083/jcb.202012095 contributor: fullname: Panicker – volume: 1319 start-page: 118 year: 2010 ident: ref_205 article-title: Clinical utility of copper, ceruloplasmin, and metallothionein plasma determinations in human neurodegenerative patients and their first-degree relatives publication-title: Brain Res. doi: 10.1016/j.brainres.2009.11.085 contributor: fullname: Arnal – volume: 706 start-page: 75 year: 2019 ident: ref_238 article-title: Dopamine β Hydroxylase (DBH) is a potential modifier gene associated with Parkinson’s disease in Eastern India publication-title: Neurosci. Lett. doi: 10.1016/j.neulet.2019.05.015 contributor: fullname: Ghosh – volume: 88 start-page: 2535 year: 2010 ident: ref_213 article-title: Peptidylgycine α-amidating monooxygenase and copper: A gene-nutrient interaction critical to nervous system function publication-title: J. Neurosci. Res. doi: 10.1002/jnr.22404 contributor: fullname: Mains – volume: 18 start-page: 597 year: 2007 ident: ref_104 article-title: Transcuprein is a macroglobulin regulated by copper and iron availability publication-title: J. Nutr. Biochem. doi: 10.1016/j.jnutbio.2006.11.005 contributor: fullname: Liu – volume: 7 start-page: S70 year: 2019 ident: ref_194 article-title: New tools for Wilson’s disease diagnosis: Exchangeable copper fraction publication-title: Ann. Transl. Med. doi: 10.21037/atm.2019.03.02 contributor: fullname: Woimant – volume: 367 start-page: 110173 year: 2022 ident: ref_72 article-title: Essential metals in health and disease publication-title: Chem. Biol. Interact. doi: 10.1016/j.cbi.2022.110173 contributor: fullname: Jomova – volume: 317 start-page: 1220 year: 2007 ident: ref_140 article-title: A microRNA feedback circuit in midbrain dopamine neurons publication-title: Science doi: 10.1126/science.1140481 contributor: fullname: Kim – volume: 37 start-page: 1 year: 2021 ident: ref_9 article-title: Environmental and occupational exposure to metals (manganese, mercury, iron) and Parkinson’s disease in low and middle-income countries: A narrative review publication-title: Rev. Environ. Health contributor: fullname: Rosselli – ident: ref_125 doi: 10.1186/s13104-018-3324-7 – volume: 89 start-page: 2009S year: 2009 ident: ref_127 article-title: Methods of assessment of copper status in humans: A systematic review publication-title: Am. J. Clin. Nutr. doi: 10.3945/ajcn.2009.27230E contributor: fullname: Harvey – volume: 34 start-page: 339 year: 2002 ident: ref_128 article-title: Structural and functional insights of Wilson disease copper-transporting ATPase publication-title: J. Bioenerg. Biomembr. doi: 10.1023/A:1021245902195 contributor: fullname: Fatemi – volume: 2016 start-page: 9646057 year: 2016 ident: ref_278 article-title: Outlining a population “at risk” of Parkinson’s disease: Evidence from a case-control study publication-title: Parkinson’s Disease contributor: fullname: Schirinzi – volume: 83 start-page: 13 year: 2016 ident: ref_50 article-title: Gaucher Disease: Clinical, Biological and Therapeutic Aspects publication-title: Pathobiology doi: 10.1159/000440865 contributor: fullname: Dandana – volume: 45 start-page: 181 year: 2018 ident: ref_200 article-title: Copper dyshomeostasis in Wilson disease and Alzheimer’s disease as shown by serum and urine copper indicators publication-title: J. Trace Elem. Med. Biol. doi: 10.1016/j.jtemb.2017.11.005 contributor: fullname: Squitti – volume: 6 start-page: 34158 year: 2015 ident: ref_73 article-title: Copper activates HIF-1α/GPER/VEGF signalling in cancer cells publication-title: Oncotarget doi: 10.18632/oncotarget.5779 contributor: fullname: Rigiracciolo – volume: 23 start-page: 1655 year: 2018 ident: ref_58 article-title: Manganese metabolism in humans publication-title: Front. Biosci. doi: 10.2741/4665 contributor: fullname: Chen – volume: 83 start-page: 3257 year: 1986 ident: ref_160 article-title: Characterization, mapping, and expression of the human ceruloplasmin gene publication-title: Proc. Natl. Acad. Sci. USA doi: 10.1073/pnas.83.10.3257 contributor: fullname: Yang – volume: 275 start-page: 7455 year: 2000 ident: ref_227 article-title: Brain copper content and cuproenzyme activity do not vary with prion protein expression level publication-title: J. Biol. Chem. doi: 10.1074/jbc.275.11.7455 contributor: fullname: Waggoner – volume: 1005 start-page: 63 year: 2017 ident: ref_52 article-title: Trace elements and healthcare: A bioinformatics perspective publication-title: Adv. Exp. Med. Biol. doi: 10.1007/978-981-10-5717-5_4 contributor: fullname: Zhang – volume: 44 start-page: 215 year: 2017 ident: ref_135 article-title: Coexisting Parkinson’s and Wilson’s disease: Chance or connection? publication-title: Can. J. Neurol. Sci. doi: 10.1017/cjn.2016.327 contributor: fullname: Alonso – volume: 275 start-page: 4305 year: 2000 ident: ref_162 article-title: Alternative RNA splicing generates a glycosylphosphatidylinositol-anchored form of ceruloplasmin in mammalian brain publication-title: J. Biol. Chem. doi: 10.1074/jbc.275.6.4305 contributor: fullname: Patel – volume: 125 start-page: 1027 year: 2018 ident: ref_285 article-title: Correlations between abnormal iron metabolism and non-motor symptoms in Parkinson’s disease publication-title: J. Neural Transm. doi: 10.1007/s00702-018-1889-x contributor: fullname: Xu – volume: 18 start-page: 511 year: 2010 ident: ref_101 article-title: Menkes disease publication-title: Eur. J. Hum. Genet. doi: 10.1038/ejhg.2009.187 – volume: 20 start-page: 627 year: 2007 ident: ref_123 article-title: Hepatic copper-transporting ATPase ATP7B: Function and inactivation at the molecular and cellular level publication-title: Biometals doi: 10.1007/s10534-006-9074-3 contributor: fullname: Bartee – volume: 26 start-page: 7760 year: 1987 ident: ref_165 article-title: Isolation and characterization of a processed gene for human ceruloplasmin publication-title: Biochemistry doi: 10.1021/bi00398a034 contributor: fullname: Koschinsky – volume: 306 start-page: 98 year: 2011 ident: ref_60 article-title: Dietary intake of metals and risk of Parkinson’s disease: A case-control study in Japan publication-title: J. Neurol. Sci. doi: 10.1016/j.jns.2011.03.035 contributor: fullname: Miyake – ident: ref_180 doi: 10.3390/ijms221910704 – ident: ref_229 doi: 10.20944/preprints201811.0279.v1 – volume: 23 start-page: 24 year: 1983 ident: ref_59 article-title: Possible contributions of nutritional interactions to copper deficiency in ruminants in South Australia publication-title: Aust. J. Exp. Agric. Anim. Husb. doi: 10.1071/EA9830024 contributor: fullname: Merry – volume: 164 start-page: 596 year: 2018 ident: ref_132 article-title: Role of copper dyshomeostasis in the pathogenesis of Parkinson’s disease publication-title: Bull. Exp. Biol. Med. doi: 10.1007/s10517-018-4039-4 contributor: fullname: Karpenko – volume: 96 start-page: 137 year: 2020 ident: ref_11 article-title: New markers in Parkinson’s disease publication-title: Adv. Clin. Chem. doi: 10.1016/bs.acc.2019.12.001 contributor: fullname: Bougea – volume: 11 start-page: 429 year: 2019 ident: ref_78 article-title: Copper affects the binding of HIF-1α to the critical motifs of its target genes publication-title: Metallomics doi: 10.1039/C8MT00280K contributor: fullname: Wu – volume: 74 start-page: 230 year: 2019 ident: ref_54 article-title: The role of zinc, copper, manganese and iron in neurodegenerative diseases publication-title: Neurotoxicology doi: 10.1016/j.neuro.2019.07.007 contributor: fullname: Mezzaroba – volume: 10 start-page: 1723 year: 2018 ident: ref_107 article-title: The N-terminal 14-mer model peptide of human Ctr1 can collect Cu(ii) from albumin. Implications for copper uptake by Ctr1 publication-title: Metallomics doi: 10.1039/C8MT00274F contributor: fullname: Stefaniak – volume: 243 start-page: G226 year: 1982 ident: ref_159 article-title: A comparison of copper-loading disease in Bedlington terriers and Wilson’s disease in humans publication-title: Am. J. Physiol. contributor: fullname: Su – volume: 40 start-page: 749 year: 2007 ident: ref_197 article-title: Percentage non-ceruloplasmin bound copper publication-title: Clin. Biochem. doi: 10.1016/j.clinbiochem.2007.04.002 contributor: fullname: Twoney – volume: 476 start-page: 22 year: 2008 ident: ref_102 article-title: Cellular multitasking: The dual role of human Cu-ATPases in cofactor delivery and intracellular copper balance publication-title: Arch. Biochem. Biophys. doi: 10.1016/j.abb.2008.05.005 contributor: fullname: Lutsenko – volume: 15 start-page: 1257 year: 2016 ident: ref_8 article-title: The epidemiology of Parkinson’s disease: Risk factors and prevention publication-title: Lancet Neurol. doi: 10.1016/S1474-4422(16)30230-7 contributor: fullname: Ascherio – volume: 46 start-page: S30 year: 2018 ident: ref_7 article-title: Neuropathology of Parkinson disease publication-title: Parkinsonism Relat. Disord. doi: 10.1016/j.parkreldis.2017.07.033 contributor: fullname: Dickson – volume: 14 start-page: 36 year: 2019 ident: ref_49 article-title: Glucocerebrosidase and its relevance to Parkinson disease publication-title: Mol. Neurodegeer. doi: 10.1186/s13024-019-0336-2 contributor: fullname: Do – volume: 50 start-page: 94 year: 2020 ident: ref_111 article-title: Modular biogenesis of mitochondrial respiratory complexes publication-title: Mitochondrion doi: 10.1016/j.mito.2019.10.008 contributor: fullname: Barros – volume: 31 start-page: 18568 year: 2011 ident: ref_221 article-title: Ceruloplasmin oxidation, a feature of Parkinson’s disease CSF, inhibits ferroxidase activity and promotes cellular iron retention publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.3768-11.2011 contributor: fullname: Olivieri – volume: 9 start-page: 371 year: 2016 ident: ref_265 article-title: Menkes disease: What a multidisciplinary approach can do publication-title: J. Multidiscip. Healthc. doi: 10.2147/JMDH.S93454 contributor: fullname: Ojha – ident: ref_29 doi: 10.3390/genes12071006 – volume: 22 start-page: 277 year: 2010 ident: ref_241 article-title: The interlobular distribution of copper in the liver of beef calves on a high-copper diet publication-title: J. Vet. Diagn. Investig. doi: 10.1177/104063871002200221 contributor: fullname: Miranda – volume: 208 start-page: 1028 year: 1995 ident: ref_161 article-title: Fine structure of the human ceruloplasmin gene publication-title: Biochem. Biophys. Res. Commun. doi: 10.1006/bbrc.1995.1437 contributor: fullname: Daimon – volume: 8 start-page: 1012 year: 2016 ident: ref_237 article-title: Copper, zinc and calcium: Imaging and quantification in anterior pituitary secretory granules publication-title: Metallomics doi: 10.1039/C6MT00079G contributor: fullname: Bonnemaison – ident: ref_223 doi: 10.3390/ijms23031435 – ident: ref_281 doi: 10.1007/978-3-211-33328-0_24 – volume: 8 start-page: 887 year: 2016 ident: ref_106 article-title: Ceruloplasmin and other copper binding components of blood plasma and their functions: An update publication-title: Metallomics doi: 10.1039/C6MT00103C contributor: fullname: Linder – volume: 47 start-page: 351 year: 2004 ident: ref_53 article-title: What are trace elements? Their deficiency and excess states publication-title: JMAJ contributor: fullname: Wada – volume: 42 start-page: 1321 year: 2022 ident: ref_46 article-title: Mitophagy, a Form of Selective Autophagy, Plays an Essential Role in Mitochondrial Dynamics of Parkinson’s Disease publication-title: Cell. Mol. Neurobiol. doi: 10.1007/s10571-021-01039-w contributor: fullname: Wang – volume: 32 start-page: 353 year: 2017 ident: ref_271 article-title: Role of Iron and Copper in the Pathogenesis of Parkinson’s Disease publication-title: Indian J. Clin. Biochem. doi: 10.1007/s12291-016-0614-5 contributor: fullname: Gangania – volume: 317 start-page: 51 year: 1996 ident: ref_232 article-title: Human extracellular superoxide dismutase is a tetramer composed of two disulphide-linked dimers: A simplified, high-yield purification of extracellular superoxide dismutase publication-title: Biochem. J. doi: 10.1042/bj3170051 contributor: fullname: Oury – volume: 113 start-page: 1745 year: 2013 ident: ref_61 article-title: Inborn errors of copper metabolism publication-title: Handb. Clin. Neurol. doi: 10.1016/B978-0-444-59565-2.00045-9 contributor: fullname: Kaler – volume: 210 start-page: 107 year: 1995 ident: ref_211 article-title: Alterations of rat brain peptidylglycine alpha-amidating monooxygenase and other cuproenzyme activities following perinatal copper deficiency publication-title: Proc. Soc. Exp. Biol. Med. doi: 10.3181/00379727-210-43929 contributor: fullname: Prohaska – volume: 55 start-page: 73 year: 2018 ident: ref_3 article-title: Genetics of Parkinson’s disease and related disorders publication-title: J. Med. Genet. doi: 10.1136/jmedgenet-2017-105047 contributor: fullname: Zhang – ident: ref_206 doi: 10.1371/journal.pone.0038327 – ident: ref_172 doi: 10.1371/currents.tol.574bcb0f133fe52835911abc4e296141 – volume: 59 start-page: 76 year: 2013 ident: ref_277 article-title: Heavy metals in blood and urine and its relation to depressive symptoms in Parkinson’s disease patients publication-title: Fukushima J. Med. Sci. doi: 10.5387/fms.59.76 contributor: fullname: Fukushima – volume: 25 start-page: 302 year: 2000 ident: ref_26 article-title: Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase publication-title: Nat. Genet. doi: 10.1038/77060 contributor: fullname: Shimura – volume: 43 start-page: 126 year: 2017 ident: ref_168 article-title: Ceruloplasmin gene expression profile changes in the rat mammary gland during pregnancy, lactation and involution publication-title: J. Trace Elem. Med. Biol. doi: 10.1016/j.jtemb.2016.12.013 contributor: fullname: Platonova – volume: 115 start-page: 247 year: 2005 ident: ref_167 article-title: The revelation of expressing region in the processed ceruloplasmin gene in human genome by biocomputational and biochemical methods publication-title: Biophys. Chem. doi: 10.1016/j.bpc.2004.12.014 contributor: fullname: Platonova – volume: 68 start-page: 125 year: 2023 ident: ref_18 article-title: Molecular genetics of Parkinson’s disease: Contributions and global trends publication-title: J. Hum. Genet. doi: 10.1038/s10038-022-01058-5 contributor: fullname: Funayama |
| SSID | ssj0000913809 |
| Score | 2.3088903 |
| SecondaryResourceType | review_article |
| Snippet | In the last 15 years, among the many reasons given for the development of idiopathic forms of Parkinson’s disease (PD), copper imbalance has been identified as... |
| SourceID | doaj pubmedcentral proquest gale crossref |
| SourceType | Open Website Open Access Repository Aggregation Database |
| StartPage | 1654 |
| SubjectTerms | Alzheimer's disease Cerebrospinal fluid Ceruloplasmin Copper CP protein Endoplasmic reticulum Enzymes Genes Genetic aspects Genotype & phenotype Homeostasis Inborn errors of metabolism Kinases Meta-analysis Metabolism Mitochondria Movement disorders Mutation Nervous system Neurodegenerative diseases Neurons Organisms Oxidases Oxidative stress Parkinson's disease Phenotypes Physiological aspects Physiology Proteins Quality control Review serum ceruloplasmin serum copper level |
| SummonAdditionalLinks | – databaseName: Directory of Open Access Journals dbid: DOA link: http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Li9swEBZtTu2h9Emzj6JCoSezsmJJ1jGbZsmplD6gNyHrQUIXOazXyx73b_Tv7S_ZGdsJcXvopVdJYGlG0nwjz3xDyAcwQVXOPM-C5TIrVCWySsaYFQAOnM1nsq9FsPqmPv8sPy2RJmdf6gtjwnp64F5wZ1JwJxzTrIKLFO1XoSKTHgxv7rXwvePD5IEz1d3BOp-VTPcsjTPw688sBg_eYqYo5u-MrFBH1v_3lfxnmOSB3bl4Tp4NgJHO-4m-II9CekmeHtAIviJxXiWEnpcdOyrdJLqot9twRRFJtg3dqSB4is-u1Ca6vAw3XcPXTfOL1pFi9nOXCHZ_97uhX9Yh1fg6Sw-Cil6THxfL74tVNtRPyJxg-XXmVRHz6CwTlQMk4Z123CldORBpwbwTQXqOdey8t1p6wWQANSltAQaBbOPsDZmkOoW3hHKw8lXJrUQ2eLhbSxm0jj46dGsBgU3Jx508zbanyTDgXqDkzVjyU3KO4t6PQnrrrgGUbgalm38pHT6HyjJ4CEE1zg65BDBZpLMycyWlBnCnyik52enTDKezMbyEXoSSckre77vhXOHPEptC3eIYhdSHgsPaytE-GE193JM2646hO0epykIc_Y_FHpMnWOMeH7I5PyGT66s2nJLHjW_fdZv-AYySB1Q priority: 102 providerName: Directory of Open Access Journals |
| Title | Abnormalities in Copper Status Associated with an Elevated Risk of Parkinson’s Phenotype Development |
| URI | https://www.proquest.com/docview/2869223246 https://search.proquest.com/docview/2870143520 https://pubmed.ncbi.nlm.nih.gov/PMC10525645 https://doaj.org/article/652c5c090b284081947f06d6171d95d1 |
| Volume | 12 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwELbYnuCAKA-xpVRGQuKUruONnfi4bLfqBVTxkLhFftIVW2e16SKO_A3-Xn9JZ7xJtYEbV9tRJjO25_Nk5jMhb8EFmZw5nnnNZVaURmRGhpAVAA6szqdydxfBxefy47fqbIE0ObKvhUlJ-9YsT-Pq-jQur1Ju5fraTvo8scnlh3mOl6_JQkxGZATgcO-MnvZflU8rpnYMjVM40080Jg7-wipRrN0ZeKBE1P_vdvx3iuSezzl_Qh53YJHOdkIdkgc-PiWP9igEn5EwMxFh5yoxo9JlpPNmvfYbiihy29Je_d5RDLlSHeli5X-mhk_L9gdtAsXK51QEdvv7T0svr3xsMDJL9xKKnpOv54sv84usuzshs4LlN5kri5AHq5kwFlCEs8pyWypjBbcFc1Z46Tiq0TmtpBNMejBRqTQo1ikRpi_IQWyif0koBw9vKq4lMsHDvlpJr1RwweKRFtDXmLzr9VmvdxQZNRwtUPP1UPNj8h7VfT8Kqa1TQ7P5XncGriVIKCxTzIDnRMBSlIFJB0grB8FcDq9DY9W4AME0Vnd1BCAsUlnVs1JKBcCurMbkuLdn3a3MtuYV9CKMlGPy5r4b1hT-KNHRN1scUyLtoeDwbdVgHgxEH_bAZE3s3P3kPPr_R1-Rh3irPYauOT8mBzebrX9NRq3bnqSYwUma8HfwmAkx |
| link.rule.ids | 230,315,729,782,786,866,887,2106,27933,27934,53800,53802 |
| linkProvider | National Library of Medicine |
| linkToHtml | http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3NbtQwELZoOUAP_CO2FDASEqd0E2_sxMdl2WoRbVVBkbhZjn_oiq2z2nQRR16D1-NJmPEm1QZuvdqOMs54PN84M58JeQMuqMpSyxKnmUjyouJJJbxPcgAHRmcjsbmLYPa5OP1avp8iTY7oamFi0r6p5odhcXkY5hcxt3J5aYZdntjw7GSS4eVrIufDHXIbDDZNt6L0uAPLDFrlhqNxBFH9UGPq4E-sE8XqnZ4PilT9_2_I_yZJbnmdo_s3lfcBudfiTDre9D8kt1x4RPa22AcfEz-uAiLWRSRVpfNAJ_Vy6VYUAei6oZ3mnKV4Wkt1oNOF-xEbPs2b77T2FIumY_3Yn1-_G3p24UKNh7p0KxfpCflyND2fzJL22oXE8DS7SmyR-8wbnfLKAACxRhpmClkZzkyeWsOdsAxnZK2WwvJUONBuITXM0UruR0_JbqiDe0YoA3BQlUwLJJGHLbkUTkpvvcFoGIDbgLztFKGWG3YNBVEJqkz1VTYg71BP16OQFTs21Ktvqv3WSoCE3KQyrcDpItbJC58KCyAtA8FsBq9DLSu0XdCp0W0JAgiLLFhqXAghARMW5YAcdAtBtUbdKFZCLyJQMSCvr7vBHPEfiw6uXuOYAhkTOYO5lb0F1BO93wPrJhJ7d-tk_-aPviJ3Zucnx-r4w-nH5-QuA0iGJ-CMHZDdq9XavSA7jV2_jPbyF8mUHfE |
| linkToPdf | http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Lj9MwELbYRUJw4L2isICRkDhlk7iJE3Mr3VaLgFXFQ-JmOX6wFV0naraII3-Dv8cvYcZNVg3c4Go7yjgz4_nszHwm5DmEoCpNDIusYjzKiiqPKu5clAE40Cod8-1dBCcfitPP5fEMaXJe9rUwIWlfV8sjvzo_8suzkFvZnOu4zxOLF--mKV6-xrM8boyL98hVcNqE7ezUwyosUmgVW57GMezsY4Xpg9-xVhQreAZxKND1_70o_5kouRN55rf-R-bb5GaHN-lkO-YOuWL9XXJjh4XwHnGTyiNyXQVyVbr0dFo3jV1TBKKblvYatIbiqS1Vns5W9ltoeL9sv9LaUSyeDnVkv378bOnizPoaD3fpTk7SffJpPvs4PYm66xcinSfpRWSKzKVOqySvNAARo4VmuhCVzpnOEqNzyw3DWRmjBDd5wi1ouRAK5mlE7sYHZN_X3j4glAFIqEqmOJLJw9JcciuEM07jrhgA3Ii86JUhmy3LhoTdCapNDtU2Iq9QV5ejkB07NNTrL7L73pKDhLlORFJB8EXMkxUu4QbAWgqCmRReh5qW6MOgV626UgQQFtmw5KTgXAA2LMoROeyNQXbO3UpWQi8iUT4izy67wS3xX4vytt7gmAKZE3MGcysHRjQQfdgDthMIvntbefjvjz4l1xbHc_n29embR-Q6A2SGB-GMHZL9i_XGPiZ7rdk8CS7zG6jZIHE |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Abnormalities+in+Copper+Status+Associated+with+an+Elevated+Risk+of+Parkinson%E2%80%99s+Phenotype+Development&rft.jtitle=Antioxidants&rft.au=Karpenko%2C+Marina+N&rft.au=Muruzheva%2C+Zamira+M&rft.au=Ekaterina+Yu+Ilyechova&rft.au=Babich%2C+Polina+S&rft.date=2023-08-22&rft.pub=MDPI+AG&rft.eissn=2076-3921&rft.volume=12&rft.issue=9&rft.spage=1654&rft_id=info:doi/10.3390%2Fantiox12091654&rft.externalDBID=HAS_PDF_LINK |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2076-3921&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2076-3921&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2076-3921&client=summon |