Salivary adenoid cystic carcinoma in Denmark 1990–2005: Outcome and independent prognostic factors including the benefit of radiotherapy. Results of the Danish Head and Neck Cancer Group (DAHANCA)

• Published in: Oral oncology Vol. 51; no. 12; pp. 1138 - 1142
• Main Authors: Bjørndal, Kristine, Krogdahl, Annelise, Therkildsen, Marianne H, Charabi, Birgitte, Kristensen, Claus A, Andersen, Elo, Schytte, Sten, Primdahl, Hanne, Johansen, Jørgen, Pedersen, Henrik B, Andersen, Lisbeth J, Godballe, Christian
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01-12-2015
• Subjects: Adenoid cystic carcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Carcinoma, Adenoid Cystic - mortality; Carcinoma, Adenoid Cystic - therapy; Child; Denmark - epidemiology; Female; Hematology, Oncology and Palliative Medicine; Humans; Male; Middle Aged; National; Neoplasm Recurrence, Local - mortality; Otolaryngology; Prognosis; Radiotherapy; Radiotherapy, Adjuvant; Salivary Gland Neoplasms - mortality; Salivary Gland Neoplasms - therapy; Survival Analysis; Treatment; Young Adult; Prognosis; Treatment; National; Radiotherapy; Adenoid cystic carcinoma
• ISSN: 1368-8375; 1879-0593
• DOI: 10.1016/j.oraloncology.2015.10.002

Highlights • A national Danish study presenting 201 patients with adenoid cystic carcinoma. • 10-year disease specific survival was 75%. • 36% experienced recurrence during follow-up (median 7.5 years). • The treatment of choice is surgery with free margins. • Adjuvant radiotherapy should be considered in selected patients.