Carried Meningococci in the Czech Republic: a Diverse Recombining Population

Author's Correction ( vol. 40 , p. 3549 ) Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue JCM About JCM Subscribers Authors Reviewers Advertisers...

Full description

Saved in:

Bibliographic Details
Published in:	Journal of Clinical Microbiology Vol. 38; no. 12; pp. 4492 - 4498
Main Authors:	JOLLEY, K. A, KALMUSOVA, J, FEIL, E. J, GUPTA, S, MUSILEK, M, KRIZ, P, MAIDEN, M. C. J
Format:	Journal Article
Language:	English
Published:	Washington, DC American Society for Microbiology 01-12-2000
Subjects:	Adolescent Adult Bacteriology Biological and medical sciences Carrier State - microbiology Czech Rep Czech Republic Epidemiology Fundamental and applied biological sciences. Psychology Humans Microbiology Neisseria meningitidis Neisseria meningitidis - classification Neisseria meningitidis - genetics Serotyping Czech Republic Europe Human Recombination Genetic variability Healthy subject Neisseriaceae Molecular epidemiology Bacteria Micrococcales Genotype Neisseria meningitidis Phylogeny Genetic transfer
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Abstract	Author's Correction ( vol. 40 , p. 3549 ) Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue JCM About JCM Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy JCM RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0095-1137 Online ISSN: 1098-660X Copyright © 2014 by the American Society for Microbiology. For an alternate route to JCM .asm.org, visit: JCM
AbstractList	Author's Correction ( vol. 40 , p. 3549 ) Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue JCM About JCM Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy JCM RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0095-1137 Online ISSN: 1098-660X Copyright © 2014 by the American Society for Microbiology. For an alternate route to JCM .asm.org, visit: JCM Population and evolutionary analyses of pathogenic bacteria are frequently hindered by sampling strategies that concentrate on isolates from patients with invasive disease. This is especially so for the gram-negative diplococcus Neisseria meningitidis, a cause of septicemia and meningitis worldwide. Meningococcal isolate collections almost exclusively comprise organisms originating from patients with invasive meningococcal disease, although this bacterium is a commensal inhabitant of the human nasopharynx and very rarely causes pathological effects. In the present study, molecular biology-based techniques were used to establish the genetic relationships of 156 meningococci isolated from healthy young adults in the Czech Republic during 1993. None of the individuals sampled had known links to patients with invasive disease. Multilocus sequence typing (MLST) showed that the bacterial population was highly diverse, comprising 71 different sequence types (STs) which were assigned to 34 distinct complexes or lineages. Three previously identified hyperinvasive lineages were present: 26 isolates (17%) belonged to the ST-41 complex (lineage 3); 4 (2.6%) belonged to the ST-11 (electrophoretic type [ET-37]) complex, and 1 (0.6%) belonged to the ST-32 (ET-5) complex. The data were consistent with the view that most nucleotide sequence diversity resulted from the reassortment of alleles by horizontal genetic exchange. Population and evolutionary analyses of pathogenic bacteria are frequently hindered by sampling strategies that concentrate on isolates from patients with invasive disease. This is especially so for the gram-negative diplococcus Neisseria meningitidis , a cause of septicemia and meningitis worldwide. Meningococcal isolate collections almost exclusively comprise organisms originating from patients with invasive meningococcal disease, although this bacterium is a commensal inhabitant of the human nasopharynx and very rarely causes pathological effects. In the present study, molecular biology-based techniques were used to establish the genetic relationships of 156 meningococci isolated from healthy young adults in the Czech Republic during 1993. None of the individuals sampled had known links to patients with invasive disease. Multilocus sequence typing (MLST) showed that the bacterial population was highly diverse, comprising 71 different sequence types (STs) which were assigned to 34 distinct complexes or lineages. Three previously identified hyperinvasive lineages were present: 26 isolates (17%) belonged to the ST-41 complex (lineage 3); 4 (2.6%) belonged to the ST-11 (electrophoretic type [ET-37]) complex, and 1 (0.6%) belonged to the ST-32 (ET-5) complex. The data were consistent with the view that most nucleotide sequence diversity resulted from the reassortment of alleles by horizontal genetic exchange. ABSTRACT Population and evolutionary analyses of pathogenic bacteria are frequently hindered by sampling strategies that concentrate on isolates from patients with invasive disease. This is especially so for the gram-negative diplococcus Neisseria meningitidis , a cause of septicemia and meningitis worldwide. Meningococcal isolate collections almost exclusively comprise organisms originating from patients with invasive meningococcal disease, although this bacterium is a commensal inhabitant of the human nasopharynx and very rarely causes pathological effects. In the present study, molecular biology-based techniques were used to establish the genetic relationships of 156 meningococci isolated from healthy young adults in the Czech Republic during 1993. None of the individuals sampled had known links to patients with invasive disease. Multilocus sequence typing (MLST) showed that the bacterial population was highly diverse, comprising 71 different sequence types (STs) which were assigned to 34 distinct complexes or lineages. Three previously identified hyperinvasive lineages were present: 26 isolates (17%) belonged to the ST-41 complex (lineage 3); 4 (2.6%) belonged to the ST-11 (electrophoretic type [ET-37]) complex, and 1 (0.6%) belonged to the ST-32 (ET-5) complex. The data were consistent with the view that most nucleotide sequence diversity resulted from the reassortment of alleles by horizontal genetic exchange.
Author	M. Musilek S. Gupta P. Kriz E. J. Feil K. A. Jolley M. C. J. Maiden J. Kalmusova
AuthorAffiliation	Wellcome Trust Centre for the Epidemiology of Infectious Disease, Department of Zoology, University of Oxford, Oxford, OX1 3FY, United Kingdom, 1 and National Reference Laboratory for Meningococcal Infections, National Institute of Public Health, Prague, Czech Republic 2
AuthorAffiliation_xml	– name: Wellcome Trust Centre for the Epidemiology of Infectious Disease, Department of Zoology, University of Oxford, Oxford, OX1 3FY, United Kingdom, 1 and National Reference Laboratory for Meningococcal Infections, National Institute of Public Health, Prague, Czech Republic 2
Author_xml	– sequence: 1 givenname: K. A surname: JOLLEY fullname: JOLLEY, K. A organization: Wellcome Trust Centre for the Epidemiology of Infectious Disease, Department of Zoology, University of Oxford, Oxford, OX1 3FY, United Kingdom – sequence: 2 givenname: J surname: KALMUSOVA fullname: KALMUSOVA, J organization: National Reference Laboratory for Meningococcal Infections, National Institute of Public Health, Prague, Czech Republic – sequence: 3 givenname: E. J surname: FEIL fullname: FEIL, E. J organization: Wellcome Trust Centre for the Epidemiology of Infectious Disease, Department of Zoology, University of Oxford, Oxford, OX1 3FY, United Kingdom – sequence: 4 givenname: S surname: GUPTA fullname: GUPTA, S organization: Wellcome Trust Centre for the Epidemiology of Infectious Disease, Department of Zoology, University of Oxford, Oxford, OX1 3FY, United Kingdom – sequence: 5 givenname: M surname: MUSILEK fullname: MUSILEK, M organization: National Reference Laboratory for Meningococcal Infections, National Institute of Public Health, Prague, Czech Republic – sequence: 6 givenname: P surname: KRIZ fullname: KRIZ, P organization: National Reference Laboratory for Meningococcal Infections, National Institute of Public Health, Prague, Czech Republic – sequence: 7 givenname: M. C. J surname: MAIDEN fullname: MAIDEN, M. C. J organization: Wellcome Trust Centre for the Epidemiology of Infectious Disease, Department of Zoology, University of Oxford, Oxford, OX1 3FY, United Kingdom
BackLink	http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=842791$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/11101585$$D View this record in MEDLINE/PubMed
BookMark	eNqFkU1v1DAQhi1URLeFv4AikLgljO3YcRAXFL61FQj1wM3yOpNdV4m92Nki-PU42lUpJy5jyX4ez4zeC3Lmg0dCCgoVpUy9_NxdVVxVlFV13bIyF1UxAHhAVhRaVUoJ38_ICqAVJaW8OScXKd0A0LoW4hE5p5QCFUqsyLozMTrsiyv0zm-DDda6wvli3mHR_Ua7K77h_rAZnX1VmOKtu8WYMN_ZMG3cohRfw_4wmtkF_5g8HMyY8MnpvCTX799ddx_L9ZcPn7o369IKgLnc1NBwaZpewEZZydtBtIazegBmpG0FN4OABlA2qpfY570MB6okA6GGAfkleX38Ns81YW_Rz9GMeh_dZOIvHYzT_754t9PbcKtVI5nM-ouTHsOPA6ZZTy5ZHEfjMRySblhdg5DivyBVwFgDkEF1BG0MKUUc7mahoJfAdA5Mc6Up00tgS1F6CSyrT-_v8lc8JZSB5yfAJGvGIRpvXbrjVM2almbq2ZHaue3up4uoTZr0jZ3udeV_AB3fq30
CODEN	JCMIDW
CitedBy_id	crossref_primary_10_1098_rsif_2007_0229 crossref_primary_10_1084_jem_20050112 crossref_primary_10_3201_eid1005_030572 crossref_primary_10_1371_journal_ppat_1009992 crossref_primary_10_1128_CMR_19_1_142_164_2006 crossref_primary_10_1096_fj_11_183590 crossref_primary_10_1371_journal_pcbi_1000455 crossref_primary_10_1038_srep41126 crossref_primary_10_1111_j_1758_2229_2009_00131_x crossref_primary_10_1099_mic_0_2007_014761_0 crossref_primary_10_1016_j_micinf_2005_12_013 crossref_primary_10_1186_1741_7007_5_35 crossref_primary_10_1128_JCM_43_9_4865_4867_2005 crossref_primary_10_1371_journal_ppat_1000020 crossref_primary_10_1128_JCM_42_4_1764_1765_2004 crossref_primary_10_1128_JCM_00038_12 crossref_primary_10_1128_JCM_44_3_1127_1131_2006 crossref_primary_10_1016_S1473_3099_10_70251_6 crossref_primary_10_1128_IAI_02001_14 crossref_primary_10_1128_IAI_00293_06 crossref_primary_10_1016_j_ijmm_2004_12_005 crossref_primary_10_1099_mic_0_28620_0 crossref_primary_10_3201_eid0805_010227 crossref_primary_10_1371_journal_ppat_1000405 crossref_primary_10_1099_mic_0_046946_0 crossref_primary_10_1586_eri_11_89 crossref_primary_10_1080_14787210_2017_1333422 crossref_primary_10_1086_527401 crossref_primary_10_1111_j_1600_0463_2005_apm1130305_x crossref_primary_10_2217_fmb_14_24 crossref_primary_10_1017_S0950268811001865 crossref_primary_10_1016_j_meegid_2009_08_008 crossref_primary_10_1073_pnas_0400695101 crossref_primary_10_1016_j_vaccine_2009_04_063 crossref_primary_10_1186_1471_2334_10_175 crossref_primary_10_1016_j_vaccine_2009_04_061 crossref_primary_10_1128_JCM_43_9_4649_4653_2005 crossref_primary_10_3390_microorganisms9030519 crossref_primary_10_1099_00221287_148_6_1813 crossref_primary_10_1371_journal_ppat_1001055 crossref_primary_10_1016_S0213_005X_04_73045_1 crossref_primary_10_1007_s00112_004_0922_3 crossref_primary_10_1099_mic_0_031534_0 crossref_primary_10_1128_mSphere_00060_20 crossref_primary_10_1111_j_1469_0691_2008_01955_x crossref_primary_10_1128_JB_186_20_6970_6982_2004 crossref_primary_10_1371_journal_ppat_1004160 crossref_primary_10_1016_S0966_842X_02_02402_2 crossref_primary_10_1128_IAI_72_1_559_569_2004 crossref_primary_10_1128_IAI_73_4_2424_2432_2005 crossref_primary_10_1016_j_tim_2003_08_006 crossref_primary_10_1016_j_patbio_2005_09_002 crossref_primary_10_1371_journal_pone_0017145 crossref_primary_10_1073_pnas_0406993102 crossref_primary_10_1099_acmi_0_000157 crossref_primary_10_1146_annurev_micro_59_030804_121325 crossref_primary_10_1016_j_tim_2004_06_003 crossref_primary_10_1007_s00430_010_0149_y crossref_primary_10_1016_j_vaccine_2007_04_041 crossref_primary_10_1097_INF_0000000000000853 crossref_primary_10_1128_JCM_00005_08 crossref_primary_10_1128_JCM_42_11_5146_5153_2004 crossref_primary_10_1128_JB_01947_07 crossref_primary_10_1371_journal_pone_0003885 crossref_primary_10_3390_pathogens9010010 crossref_primary_10_1371_journal_pone_0022685 crossref_primary_10_1098_rspb_2009_2033 crossref_primary_10_1016_j_meegid_2014_12_027 crossref_primary_10_1099_jmm_0_45529_0 crossref_primary_10_1111_1469_0691_12647 crossref_primary_10_1586_14760584_2015_1004317 crossref_primary_10_1371_journal_ppat_1002403 crossref_primary_10_1128_JB_186_5_1518_1530_2004 crossref_primary_10_1128_JCM_01079_12 crossref_primary_10_1371_journal_ppat_1005078 crossref_primary_10_1128_JCM_43_10_5129_5135_2005 crossref_primary_10_1128_JB_00883_10 crossref_primary_10_1371_journal_pone_0073066 crossref_primary_10_1093_molbev_msi041 crossref_primary_10_1098_rstb_2006_1918 crossref_primary_10_1073_pnas_0704152104 crossref_primary_10_1128_JCM_39_1_14_23_2001 crossref_primary_10_1016_j_meegid_2008_04_002 crossref_primary_10_1128_CVI_00133_14 crossref_primary_10_1128_JCM_00019_06 crossref_primary_10_1111_j_1574_6976_2006_00056_x crossref_primary_10_1073_pnas_0712019105 crossref_primary_10_1371_journal_ppat_1000297 crossref_primary_10_1073_pnas_0402000101 crossref_primary_10_1111_j_1574_6976_2006_00052_x crossref_primary_10_3201_eid0809_02_0122 crossref_primary_10_1038_nrmicro1236 crossref_primary_10_1016_j_diagmicrobio_2005_06_015 crossref_primary_10_1128_JCM_44_4_1509_1518_2006 crossref_primary_10_2165_00148581_200406040_00004 crossref_primary_10_1128_JCM_39_4_1235_1240_2001 crossref_primary_10_1128_JB_185_11_3307_3316_2003 crossref_primary_10_1016_S0264_410X_01_00410_8 crossref_primary_10_1179_2047773213Y_0000000119 crossref_primary_10_1128_IAI_72_7_4217_4223_2004 crossref_primary_10_1016_j_mimet_2015_10_009 crossref_primary_10_1016_j_ijantimicag_2006_11_002 crossref_primary_10_1038_srep21015 crossref_primary_10_1099_jmm_0_45541_0 crossref_primary_10_1186_1471_2105_5_86 crossref_primary_10_1016_j_ijmm_2004_06_027 crossref_primary_10_1186_s12864_017_3616_7 crossref_primary_10_1097_MRM_0000000000000016 crossref_primary_10_1128_JCM_01653_09 crossref_primary_10_1046_j_1432_1033_2003_03535_x crossref_primary_10_1534_genetics_105_044917 crossref_primary_10_1073_pnas_0800151105 crossref_primary_10_1080_15275920490887968 crossref_primary_10_1016_j_jtbi_2005_08_037 crossref_primary_10_1016_j_meegid_2005_02_003 crossref_primary_10_1128_JCM_42_7_2898_2901_2004 crossref_primary_10_1093_infdis_jir466 crossref_primary_10_3201_eid0809_020122 crossref_primary_10_1016_S0161_5890_03_00162_7
Cites_doi	10.1093/infdis/169.3.673 10.1007/BF00415492 10.1093/oxfordjournals.molbev.a026159 10.1017/S0950268898001496 10.1128/JCM.37.12.3883-3887.1999 10.1093/jac/18.Supplement_A.25 10.1093/oxfordjournals.molbev.a026061 10.1073/pnas.90.10.4384 10.1093/clinids/5.1.71 10.1016/S1438-4221(00)80089-2 10.1001/jama.1995.03520290042027 10.1046/j.1365-2958.1996.981457.x 10.1007/BF02900361 10.1017/S0950268898008930 10.1017/S0950268898001769 10.1016/S0140-6736(99)00252-4 10.1128/jb.169.6.2781-2792.1987 10.1128/JB.181.18.5551-5556.1999 10.1111/j.1699-0463.1998.tb01379.x 10.1017/S0950268800050196 10.1128/iai.56.8.2060-2068.1988 10.1093/genetics/154.4.1439 10.1086/515622 10.1017/S0950268896007261 10.1093/bioinformatics/14.1.68 10.1111/j.1574-6968.1988.tb02366.x 10.1073/pnas.83.13.4927 10.1016/S0923-2508(99)80052-7 10.1073/pnas.95.6.3140
ContentType	Journal Article
Copyright	2001 INIST-CNRS Copyright © 2000, American Society for Microbiology 2000
Copyright_xml	– notice: 2001 INIST-CNRS – notice: Copyright © 2000, American Society for Microbiology 2000
DBID	IQODW CGR CUY CVF ECM EIF NPM AAYXX CITATION 7QL C1K 7X8 5PM
DOI	10.1128/JCM.38.12.4492-4498.2000
DatabaseName	Pascal-Francis Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef Bacteriology Abstracts (Microbiology B) Environmental Sciences and Pollution Management MEDLINE - Academic PubMed Central (Full Participant titles)
DatabaseTitle	MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef Bacteriology Abstracts (Microbiology B) Environmental Sciences and Pollution Management MEDLINE - Academic
DatabaseTitleList	MEDLINE Bacteriology Abstracts (Microbiology B) CrossRef
Database_xml	– sequence: 1 dbid: ECM name: MEDLINE url: https://search.ebscohost.com/login.aspx?direct=true&db=cmedm&site=ehost-live sourceTypes: Index Database
DeliveryMethod	fulltext_linktorsrc
Discipline	Medicine Biology
EISSN	1098-660X
EndPage	4498
ExternalDocumentID	10_1128_JCM_38_12_4492_4498_2000 11101585 842791 jcm_38_12_4492
Genre	Research Support, Non-U.S. Gov't Journal Article
GeographicLocations	Czech Republic Europe
GeographicLocations_xml	– name: Czech Republic
GrantInformation_xml	– fundername: Wellcome Trust
GroupedDBID	--- .55 .GJ 08R 0R~ 18M 29K 2WC 39C 3O- 4.4 41~ 53G 5GY 5RE 5VS AAUGY AAYOK ABOCM ABPPZ ACGFO ADBBV AENEX AFMIJ AGCDD AI. ALMA_UNASSIGNED_HOLDINGS AOIJS BAWUL BTFSW CS3 D-I DIK DU5 E3Z EBS EJD F5P FRP GX1 H13 HF~ HYE HZ~ H~9 IQODW KQ8 L7B O9- OHT OK1 P2P P6G RHF RHI RNS RPM RSF TR2 UCJ VH1 W8F WHG WOQ X7M ZA5 ZCA ZGI ZXP ~KM AGVNZ CGR CUY CVF ECM EIF NPM AAYXX CITATION 7QL C1K 7X8 5PM
ID	FETCH-LOGICAL-c500t-b40736a7d50b8c639f59a324f02a6c953af5070e678d6ed000a301862058ffe3
IEDL.DBID	RPM
ISSN	0095-1137
IngestDate	Tue Sep 17 21:28:22 EDT 2024 Fri Oct 25 03:23:52 EDT 2024 Fri Oct 25 02:16:11 EDT 2024 Thu Sep 12 17:24:17 EDT 2024 Sat Sep 28 08:22:08 EDT 2024 Sun Oct 22 16:09:32 EDT 2023 Wed May 18 15:27:01 EDT 2016
IsDoiOpenAccess	false
IsOpenAccess	true
IsPeerReviewed	true
IsScholarly	true
Issue	12
Keywords	Human Recombination Genetic variability Healthy subject Neisseriaceae Molecular epidemiology Bacteria Micrococcales Genotype Neisseria meningitidis Phylogeny Genetic transfer
Language	English
License	CC BY 4.0
LinkModel	DirectLink
MergedId	FETCHMERGED-LOGICAL-c500t-b40736a7d50b8c639f59a324f02a6c953af5070e678d6ed000a301862058ffe3
Notes	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Article-1 ObjectType-Feature-2 Corresponding author. Mailing address: Wellcome Trust Centre for the Epidemiology of Infectious Disease, Department of Zoology, University of Oxford, South Parks Road, Oxford, OX1 3FY, United Kingdom. Phone: 44 (1865) 271284. Fax: 44 (1865) 271284. E-mail: martin.maiden@zoo.ox.ac.uk.
OpenAccessLink	https://jcm.asm.org/content/jcm/38/12/4492.full.pdf
PMID	11101585
PQID	18022700
PQPubID	23462
PageCount	7
ParticipantIDs	pubmedcentral_primary_oai_pubmedcentral_nih_gov_87626 proquest_miscellaneous_18022700 proquest_miscellaneous_72440565 highwire_asm_jcm_38_12_4492 pubmed_primary_11101585 crossref_primary_10_1128_JCM_38_12_4492_4498_2000 pascalfrancis_primary_842791
PublicationCentury	2000
PublicationDate	2000-12-01
PublicationDateYYYYMMDD	2000-12-01
PublicationDate_xml	– month: 12 year: 2000 text: 2000-12-01 day: 01
PublicationDecade	2000
PublicationPlace	Washington, DC
PublicationPlace_xml	– name: Washington, DC – name: United States
PublicationTitle	Journal of Clinical Microbiology
PublicationTitleAlternate	J Clin Microbiol
PublicationYear	2000
Publisher	American Society for Microbiology
Publisher_xml	– name: American Society for Microbiology
References	e_1_3_2_29_2 e_1_3_2_20_2 e_1_3_2_21_2 e_1_3_2_22_2 e_1_3_2_24_2 Kremastinou J. (e_1_3_2_23_2) 1999; 23 Krizova P. (e_1_3_2_26_2) 1997; 5 e_1_3_2_9_2 e_1_3_2_15_2 e_1_3_2_38_2 e_1_3_2_8_2 e_1_3_2_16_2 e_1_3_2_37_2 e_1_3_2_7_2 e_1_3_2_17_2 Kuzemenska P. (e_1_3_2_28_2) 1987 e_1_3_2_6_2 e_1_3_2_18_2 e_1_3_2_39_2 e_1_3_2_19_2 e_1_3_2_30_2 e_1_3_2_32_2 e_1_3_2_10_2 e_1_3_2_31_2 e_1_3_2_5_2 e_1_3_2_11_2 e_1_3_2_34_2 e_1_3_2_4_2 e_1_3_2_12_2 Krizova P. (e_1_3_2_25_2) 1995; 3 e_1_3_2_33_2 e_1_3_2_3_2 e_1_3_2_13_2 e_1_3_2_36_2 e_1_3_2_2_2 e_1_3_2_14_2 e_1_3_2_35_2 Kumar S. (e_1_3_2_27_2) 1994; 10
References_xml	– ident: e_1_3_2_37_2 doi: 10.1093/infdis/169.3.673 – ident: e_1_3_2_13_2 doi: 10.1007/BF00415492 – ident: e_1_3_2_20_2 doi: 10.1093/oxfordjournals.molbev.a026159 – volume: 10 start-page: 189 year: 1994 ident: e_1_3_2_27_2 article-title: MEGA: molecular evolutionary genetics analysis software for microcomputers publication-title: Comput. Appl. Biosci. contributor: fullname: Kumar S. – ident: e_1_3_2_36_2 doi: 10.1017/S0950268898001496 – ident: e_1_3_2_17_2 doi: 10.1128/JCM.37.12.3883-3887.1999 – ident: e_1_3_2_9_2 – volume: 23 start-page: 13 year: 1999 ident: e_1_3_2_23_2 article-title: Carriage of Neisseria meningitidis and Neisseria lactamica among ethnic Greek school children from Russian immigrant families in Athens publication-title: FEMS Immunol. Med. Microbiol. contributor: fullname: Kremastinou J. – ident: e_1_3_2_7_2 doi: 10.1093/jac/18.Supplement_A.25 – ident: e_1_3_2_18_2 doi: 10.1093/oxfordjournals.molbev.a026061 – ident: e_1_3_2_34_2 doi: 10.1073/pnas.90.10.4384 – volume: 3 start-page: 189 year: 1995 ident: e_1_3_2_25_2 article-title: Changing epidemiology of meningococcal invasive disease in the Czech Republic caused by new clone Neisseria meningitidis C:2a:P1.2(P1.5), ET-15/37 publication-title: Cent. Eur. J. Public Health contributor: fullname: Krizova P. – ident: e_1_3_2_3_2 – ident: e_1_3_2_31_2 – ident: e_1_3_2_35_2 doi: 10.1093/clinids/5.1.71 – ident: e_1_3_2_29_2 doi: 10.1016/S1438-4221(00)80089-2 – ident: e_1_3_2_39_2 doi: 10.1001/jama.1995.03520290042027 – ident: e_1_3_2_32_2 doi: 10.1046/j.1365-2958.1996.981457.x – volume: 5 start-page: 214 year: 1997 ident: e_1_3_2_26_2 article-title: Development of the epidemiological situation in invasive meningococcal disease in the Czech Republic caused by emerging Neisseria meningitidis clone ET-15/37 publication-title: Cent. Eur. J. Public Health contributor: fullname: Krizova P. – ident: e_1_3_2_38_2 doi: 10.1007/BF02900361 – ident: e_1_3_2_4_2 doi: 10.1017/S0950268898008930 – ident: e_1_3_2_5_2 doi: 10.1017/S0950268898001769 – ident: e_1_3_2_33_2 doi: 10.1016/S0140-6736(99)00252-4 – ident: e_1_3_2_16_2 doi: 10.1128/jb.169.6.2781-2792.1987 – ident: e_1_3_2_8_2 doi: 10.1128/JB.181.18.5551-5556.1999 – ident: e_1_3_2_11_2 doi: 10.1111/j.1699-0463.1998.tb01379.x – ident: e_1_3_2_14_2 doi: 10.1017/S0950268800050196 – ident: e_1_3_2_15_2 doi: 10.1128/iai.56.8.2060-2068.1988 – ident: e_1_3_2_19_2 doi: 10.1093/genetics/154.4.1439 – start-page: 103 year: 1987 ident: e_1_3_2_28_2 article-title: Epidemiology of meningococcal disease in central and eastern Europe publication-title: Evolution of meningococcal disease contributor: fullname: Kuzemenska P. – ident: e_1_3_2_22_2 doi: 10.1086/515622 – ident: e_1_3_2_6_2 doi: 10.1017/S0950268896007261 – ident: e_1_3_2_10_2 – ident: e_1_3_2_21_2 doi: 10.1093/bioinformatics/14.1.68 – ident: e_1_3_2_2_2 doi: 10.1111/j.1574-6968.1988.tb02366.x – ident: e_1_3_2_12_2 doi: 10.1073/pnas.83.13.4927 – ident: e_1_3_2_24_2 doi: 10.1016/S0923-2508(99)80052-7 – ident: e_1_3_2_30_2 doi: 10.1073/pnas.95.6.3140
SSID	ssj0014455
Score	2.111637
Snippet	Author's Correction ( vol. 40 , p. 3549 ) Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike... Population and evolutionary analyses of pathogenic bacteria are frequently hindered by sampling strategies that concentrate on isolates from patients with... ABSTRACT Population and evolutionary analyses of pathogenic bacteria are frequently hindered by sampling strategies that concentrate on isolates from patients...
SourceID	pubmedcentral proquest crossref pubmed pascalfrancis highwire
SourceType	Open Access Repository Aggregation Database Index Database Publisher
StartPage	4492
SubjectTerms	Adolescent Adult Bacteriology Biological and medical sciences Carrier State - microbiology Czech Rep Czech Republic Epidemiology Fundamental and applied biological sciences. Psychology Humans Microbiology Neisseria meningitidis Neisseria meningitidis - classification Neisseria meningitidis - genetics Serotyping
Title	Carried Meningococci in the Czech Republic: a Diverse Recombining Population
URI	http://jcm.asm.org/content/38/12/4492.abstract https://www.ncbi.nlm.nih.gov/pubmed/11101585 https://search.proquest.com/docview/18022700 https://search.proquest.com/docview/72440565 https://pubmed.ncbi.nlm.nih.gov/PMC87626
Volume	38
hasFullText	1
inHoldings	1
isFullTextHit
isPrint
link	http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwEB6xlUBcEC2v0BZ84JrdxLEThxtKW1WIRRX0wM3yU92KZKtu9wC_nrGTbHcruHDxJU7kzIw939jjbwA-oBFpSm2VWnQAKXOKploVKs1dZcvcoJeIZNXn36uvP8TJaaDJKca7MDFp3-jFtPvZTrvFVcytvGnNbMwTm13MmzCDy9kEJogMxwB9ODhgjPdFC2qe5nlRjck7VMw-N_NpIcLmH2M1TbER8aJK4A1FJ5jzUE952zmNhMEhX1KtUGS-r3XxNzD6MKdyy0mdPYdnA7okn_q_2IdHrjuAx329yV8H8GQ-nKS_gC-NusUo2ZK5CzsjS1wXzYIsOoKAkDS_nbki31zPgf2RKHIS0zccCdFqq2NRCXKxqf31Ei7PTi-b83SorJAanmV3qcYwrihVZXmmhUGQ4nmtEFr5jKrS1LxQHnFi5tCT2dJZFJLChQCDn4wL713xCva6ZefeANFc1Z76jLnMM6adsNYIzRF2Ms2E4gnko0TlTc-fIWPcQYVEhchCyJzKoJDQiFAVM0vgcBS9VKtWXpt2q18CRzva2HxWMFrVeQLvR-VInCnh-EN1brleycB1F47Z_92jQqyDgBAH_bpX5v2QBwNJgO-oedMhsHTvPkHjjWzd0Vjf_ud7h_A03v2P-TNHsHd3u3bHMFnZ9bto938AZE8DSg
link.rule.ids	230,315,729,782,786,887,27935,27936,53803,53805
linkProvider	National Library of Medicine
linkToHtml	http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lc9MwEN6hZXhceJSXaaE6cHUiy1Isc2PcdgLEnQ7kwE0jyfI0DHY6TXOAX89KtkPCwKUXXyR7ZO1K-6129S3AO1Qiw1iVxRUagJg7zWKjUx0nLqsmiUUrEciqp1-z82_y5NTT5KTDXZiQtG_NYtT-aEbt4jLkVl41djzkiY0vysKv4Ml4D-7iaqXp4KL3oQPORVe2IBdxkqTZkL7D5PhTUY5S6Y__OM9ZjA8Zrqp45lA0g4nwFZW3zdNAGewzJvUKJ63uql38C47-nVW5ZabOHt_qB5_Aox6Vkg9d41O449oDuNfVqfx5APfLPgL_DGaFvkbvuiKl8ycqS9xP7YIsWoJAkhS_nL0kX1zHnf2eaHIS0j4c8V5uY0IxCnKxqRn2HOZnp_NiGvcVGWIrKL2JDbp_6URnlaBGWgQ3tcg1QrKaMj2xuUh1jfiSOrSA1cRVOLUaNxB0mqiQde3SF7DfLlv3CogROq9ZTbmjNefGyaqy0giEq9xwqUUEySAHddXxbqjgrzCpUIwqlSphyovRP6SvpkkjOBwEpvSqUd9ts9UvgqMdGW4-KznL8iSC40GkCleYD5vo1i3XK-U58nx4_v89MsRICCRx0C87Ffgz5F6tIhA7yrHp4Nm9d1tQJwLLd9CB17d87xgeTOflTM0-nn8-hIeBPyDk4BzB_s312r2BvVW1fhtWzm-XlRhw
linkToPdf	http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwELZoEVUvPMqjoYX6wDWbxLEThxvKdlWgW62gB26Wn-oikl11uwf49YydZNlFcOnFlziR4xl7vvGMv0HoHSiRIsSUsQEDEFMrSaxkLuPMlqbINFiJQFZ98bW8-sbH554mpxzuwoSkfa3mo_ZHM2rnNyG3ctnoZMgTS2bT2q_gIlkal-yhh7BiUza46X34gFLWlS6oWJxleTmk8BCefKqno5z7I0BKKxJDw8N1Fc8eCqYwY76q8raJGmiDfdakXMHEua7ixb8g6d-ZlVumavLk3j_5FD3u0Sn-0HV4hh7Y9gg96upV_jxCB9M-Ev8cXdbyFrxsg6fWn6wsYF_VczxvMQBKXP-y-gZ_sR2H9nss8Tikf1jsvd1GhaIUeLapHfYCXU_Or-uLuK_MEGuWpnexAjcwL2RpWKq4BpDjWCUBmrmUyEJXLJcOcGZqwRKawhqYXgkbCThPKePO2fwl2m8XrT1GWDFZOeJSalNHqbLcGM0VA9hKFeWSRSgbZCGWHf-GCH4L4QJEKXIuMiK8KH3DfVXNNEIng9CEXDXiu262-kXodEeOm89ySsoqi9DZIFYBK82HT2RrF-uV8Fx5Pkz__x4lYCUAlDDoV50a_Blyr1oRYjsKsungWb53n4BeBLbvoAev7_neGTqYjSfi8uPV5xN0GGgEQirOKdq_u13bN2hvZdZvw-L5DXylGvA
openUrl	ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Carried+Meningococci+in+the+Czech+Republic%3A+a+Diverse+Recombining+Population&rft.jtitle=Journal+of+clinical+microbiology&rft.au=Jolley%2C+KA&rft.au=Kalmusova%2C+J&rft.au=Feil%2C+E+J&rft.au=Gupta%2C+S&rft.date=2000-12-01&rft.issn=0095-1137&rft.volume=38&rft.issue=12&rft.spage=4492&rft.epage=4498&rft_id=info:doi/10.1128%2FJCM.38.12.4492-4498.2000&rft.externalDBID=NO_FULL_TEXT
thumbnail_l	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0095-1137&client=summon
thumbnail_m	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0095-1137&client=summon
thumbnail_s	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0095-1137&client=summon