Carpal tunnel syndrome: clinical features, diagnosis, and management

Summary Carpal tunnel syndrome is the most common peripheral nerve entrapment syndrome worldwide. The clinical symptoms and physical examination findings in patients with this syndrome are recognised widely and various treatments exist, including non-surgical and surgical options. Despite these adva...

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Published in:Lancet neurology Vol. 15; no. 12; pp. 1273 - 1284
Main Authors: Padua, Luca, Prof, Coraci, Daniele, MD, Erra, Carmen, MD, Pazzaglia, Costanza, MD, Paolasso, Ilaria, MD, Loreti, Claudia, BS, Caliandro, Pietro, MD, Hobson-Webb, Lisa D, MD
Format: Journal Article
Language:English
Published: England Elsevier Ltd 01-11-2016
Elsevier Limited
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Abstract Summary Carpal tunnel syndrome is the most common peripheral nerve entrapment syndrome worldwide. The clinical symptoms and physical examination findings in patients with this syndrome are recognised widely and various treatments exist, including non-surgical and surgical options. Despite these advantages, there is a paucity of evidence about the best approaches for assessment of carpal tunnel syndrome and to guide treatment decisions. More objective methods for assessment, including electrodiagnostic testing and nerve imaging, provide additional information about the extent of axonal involvement and structural change, but their exact benefit to patients is unknown. Although the best means of integrating clinical, functional, and anatomical information for selecting treatment choices has not yet been identified, patients can be diagnosed quickly and respond well to treatment. The high prevalence of carpal tunnel syndrome, its effects on quality of life, and the cost that disease burden generates to health systems make it important to identify the research priorities that will be resolved in clinical trials.
AbstractList Carpal tunnel syndrome is the most common peripheral nerve entrapment syndrome worldwide. The clinical symptoms and physical examination findings in patients with this syndrome are recognised widely and various treatments exist, including non-surgical and surgical options. Despite these advantages, there is a paucity of evidence about the best approaches for assessment of carpal tunnel syndrome and to guide treatment decisions. More objective methods for assessment, including electrodiagnostic testing and nerve imaging, provide additional information about the extent of axonal involvement and structural change, but their exact benefit to patients is unknown. Although the best means of integrating clinical, functional, and anatomical information for selecting treatment choices has not yet been identified, patients can be diagnosed quickly and respond well to treatment. The high prevalence of carpal tunnel syndrome, its effects on quality of life, and the cost that disease burden generates to health systems make it important to identify the research priorities that will be resolved in clinical trials.
Summary Carpal tunnel syndrome is the most common peripheral nerve entrapment syndrome worldwide. The clinical symptoms and physical examination findings in patients with this syndrome are recognised widely and various treatments exist, including non-surgical and surgical options. Despite these advantages, there is a paucity of evidence about the best approaches for assessment of carpal tunnel syndrome and to guide treatment decisions. More objective methods for assessment, including electrodiagnostic testing and nerve imaging, provide additional information about the extent of axonal involvement and structural change, but their exact benefit to patients is unknown. Although the best means of integrating clinical, functional, and anatomical information for selecting treatment choices has not yet been identified, patients can be diagnosed quickly and respond well to treatment. The high prevalence of carpal tunnel syndrome, its effects on quality of life, and the cost that disease burden generates to health systems make it important to identify the research priorities that will be resolved in clinical trials.
Author Padua, Luca, Prof
Erra, Carmen, MD
Paolasso, Ilaria, MD
Coraci, Daniele, MD
Caliandro, Pietro, MD
Pazzaglia, Costanza, MD
Hobson-Webb, Lisa D, MD
Loreti, Claudia, BS
Author_xml – sequence: 1
  fullname: Padua, Luca, Prof
– sequence: 2
  fullname: Coraci, Daniele, MD
– sequence: 3
  fullname: Erra, Carmen, MD
– sequence: 4
  fullname: Pazzaglia, Costanza, MD
– sequence: 5
  fullname: Paolasso, Ilaria, MD
– sequence: 6
  fullname: Loreti, Claudia, BS
– sequence: 7
  fullname: Caliandro, Pietro, MD
– sequence: 8
  fullname: Hobson-Webb, Lisa D, MD
BackLink https://www.ncbi.nlm.nih.gov/pubmed/27751557$$D View this record in MEDLINE/PubMed
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Snippet Summary Carpal tunnel syndrome is the most common peripheral nerve entrapment syndrome worldwide. The clinical symptoms and physical examination findings in...
Carpal tunnel syndrome is the most common peripheral nerve entrapment syndrome worldwide. The clinical symptoms and physical examination findings in patients...
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SubjectTerms Arthritis
Carpal tunnel syndrome
Carpal Tunnel Syndrome - diagnosis
Carpal Tunnel Syndrome - physiopathology
Carpal Tunnel Syndrome - therapy
Diabetes
Edema
Entrapment
Epidemiology
Humans
Hypothyroidism
Insurance claims
Neurology
Obesity
Pregnancy
Risk factors
Womens health
Title Carpal tunnel syndrome: clinical features, diagnosis, and management
URI https://www.clinicalkey.es/playcontent/1-s2.0-S1474442216302319
https://dx.doi.org/10.1016/S1474-4422(16)30231-9
https://www.ncbi.nlm.nih.gov/pubmed/27751557
https://www.proquest.com/docview/1828223306
https://search.proquest.com/docview/1835454037
Volume 15
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