Preservation of the hyperdirect pathway of basal ganglia in a rodent brain slice

• Published in: Neuroscience Vol. 215; pp. 31 - 41
• Main Authors: Bosch, C, Mailly, P, Degos, B, Deniau, J.-M, Venance, L
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier Ltd 26-07-2012; Elsevier; Elsevier - International Brain Research Organization
• Subjects: 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology; Animals; Animals, Newborn; basal ganglia; Basal Ganglia - anatomy & histology; Basal Ganglia - cytology; Basal Ganglia - physiology; Biological and medical sciences; Computer Simulation; Electric Stimulation; Excitatory Amino Acid Antagonists - pharmacology; Food and Nutrition; Frontal Lobe - physiology; Fundamental and applied biological sciences. Psychology; hyperdirect pathway; In Vitro Techniques; Life Sciences; Membrane Potentials - drug effects; Membrane Potentials - physiology; Models, Neurological; Neural Pathways - physiology; Neurobiology; Neurology; Neurons and Cognition; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Reaction Time - drug effects; Substantia Nigra - physiology; substantia nigra pars reticulata; subthalamic nucleus; synaptic transmission; Synaptic Transmission - drug effects; Valine - analogs & derivatives; Valine - pharmacology; Vertebrates: nervous system and sense organs; substantia nigra pars reticulata; basal ganglia; inhibitory post-synaptic current; excitatory post-synaptic current; hyperdirect pathway; STN; 3D; three-dimensional; CV; IPSC; SNr; subthalamic nucleus; synaptic transmission; EPSC; coefficient of variation; Vertebrata; Mammalia; Locus niger; Synaptic transmission; Central nervous system; Rodentia; Basal ganglion; Subthalamic nucleus; Encephalon
• ISSN: 0306-4522; 1873-7544
• DOI: 10.1016/j.neuroscience.2012.04.033

Highlights ► We established a rat brain slice preserving the hyperdirect pathway of basal ganglia. ► We analyzed transmission and short-term plasticity in the hyperdirect pathway. ► This new brain slice allows transmission and plasticity in the hyperdirect pathway to be studied.