Dynamics of an asymmetric bilayer lipid membrane in a viscous solvent
Bilayer lipid membranes (BLMs) are an essential component of many biological systems, forming a functional barrier between the cell and the surrounding environment. When the membrane relaxes from a structural perturbation, the dynamics of the relaxation depends on the bilayer structure. We present a...
Saved in:
| Published in: | Europhysics letters Vol. 111; no. 1; pp. 18004 - p1-18004-p6 |
|---|---|
| Main Authors: | , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
Les Ulis
EDP Sciences, IOP Publishing and Società Italiana di Fisica
01-07-2015
IOP Publishing |
| Subjects: | |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Abstract | Bilayer lipid membranes (BLMs) are an essential component of many biological systems, forming a functional barrier between the cell and the surrounding environment. When the membrane relaxes from a structural perturbation, the dynamics of the relaxation depends on the bilayer structure. We present a model of a BLM in a viscous solvent, including an explicit description of a "thick" membrane, where the fluctuations in the thickness of a monolayer leaflet are coupled to changes in the lipid density within that monolayer. We find dispersion relations describing three intuitive forms of bilayer motion, including a mode describing motion of the intermonolayer surface not noted previously in the literature. Two intrinsic length scales emerge that help characterise the dynamics; the well-known Saffman-Delbrück length and another, , resulting from the intermonolayer friction. The framework also allows for asymmetry in the BLM parameters between the monolayer leaflets, which is found to couple dynamic modes of bilayer motion. |
|---|---|
| AbstractList | Bilayer lipid membranes (BLMs) are an essential component of many biological systems, forming a functional barrier between the cell and the surrounding environment. When the membrane relaxes from a structural perturbation, the dynamics of the relaxation depends on the bilayer structure. We present a model of a BLM in a viscous solvent, including an explicit description of a "thick" membrane, where the fluctuations in the thickness of a monolayer leaflet are coupled to changes in the lipid density within that monolayer. We find dispersion relations describing three intuitive forms of bilayer motion, including a mode describing motion of the intermonolayer surface not noted previously in the literature. Two intrinsic length scales emerge that help characterise the dynamics; the well-known Saffman-Delbrück length and another, , resulting from the intermonolayer friction. The framework also allows for asymmetry in the BLM parameters between the monolayer leaflets, which is found to couple dynamic modes of bilayer motion. Bilayer lipid membranes (BLMs) are an essential component of many biological systems, forming a functional barrier between the cell and the surrounding environment. When the membrane relaxes from a structural perturbation, the dynamics of the relaxation depends on the bilayer structure. We present a model of a BLM in a viscous solvent, including an explicit description of a “thick” membrane, where the fluctuations in the thickness of a monolayer leaflet are coupled to changes in the lipid density within that monolayer. We find dispersion relations describing three intuitive forms of bilayer motion, including a mode describing motion of the intermonolayer surface not noted previously in the literature. Two intrinsic length scales emerge that help characterise the dynamics; the well-known Saffman-Delbrück length and another, $\ell_{r}$ , resulting from the intermonolayer friction. The framework also allows for asymmetry in the BLM parameters between the monolayer leaflets, which is found to couple dynamic modes of bilayer motion. Bilayer lipid membranes (BLMs) are an essential component of many biological systems, forming a functional barrier between the cell and the surrounding environment. When the membrane relaxes from a structural perturbation, the dynamics of the relaxation depends on the bilayer structure. We present a model of a BLM in a viscous solvent, including an explicit description of a "thick" membrane, where the fluctuations in the thickness of a monolayer leaflet are coupled to changes in the lipid density within that monolayer. We find dispersion relations describing three intuitive forms of bilayer motion, including a mode describing motion of the intermonolayer surface not noted previously in the literature. Two intrinsic length scales emerge that help characterise the dynamics; the well-known Saffman-Delbruck length and another, lr, resulting from the intermonolayer friction. The framework also allows for asymmetry in the BLM parameters between the monolayer leaflets, which is found to couple dynamic modes of bilayer motion. |
| Author | Smye, S. W. Olmsted, P. D. Bingham, R. J. |
| Author_xml | – sequence: 1 givenname: R. J. surname: Bingham fullname: Bingham, R. J. organization: University of York York Centre for Complex Systems Analysis, - York, YO10 5GE, UK – sequence: 2 givenname: S. W. surname: Smye fullname: Smye, S. W. organization: University of Leeds Academic Division of Medical Physics, - Leeds, LS2 9JT, UK – sequence: 3 givenname: P. D. surname: Olmsted fullname: Olmsted, P. D. organization: Georgetown University Washington DC Institute for Soft Matter Synthesis & Metrology, Department of Physics, USA |
| BookMark | eNp9kEtLAzEUhYNUsK3-AjcBN27G3ttJZpKl1vqAilAUlyEzk4HUedRkWpx_b2qLggtXd_Odew7fiAyatjGEnCNc4RTkBKaSRxxSPkHECQoAdkSGOBVJxARnAzL8IU7IyPsVAKLAZEjmt32ja5t72pZUN1T7vq5N52xOM1vp3jha2bUtaG3qzOnGUBsgurU-bzee-rbamqY7Jcelrrw5O9wxeb2bv8weosXz_ePsehHlTMou9JusKGUJBUjMMpYUsQYuGPIEU0hy1CzjqZCapajLqTBJxpkopEGGOsc4HpPL_d-1az82xneqDkNMVYVhYY7ClMccJDAW0Is_6KrduCasUzEiICShNVDxnspd670zpVo7W2vXKwS1U6t24tROnApq1bfakIr2Kes78_kT0e5dJWkcUAFvahbfLHApl-op8JMD365_Z_zX8AXbwYho |
| CODEN | EULEEJ |
| CitedBy_id | crossref_primary_10_3389_fchem_2021_642851 crossref_primary_10_1073_pnas_2004807117 crossref_primary_10_1134_S106377611706005X crossref_primary_10_1021_acs_jpclett_7b01830 crossref_primary_10_1134_S0006350917040236 crossref_primary_10_1016_j_cocis_2019_05_003 crossref_primary_10_1016_j_plipres_2022_101179 crossref_primary_10_3389_fphy_2023_1279007 crossref_primary_10_1039_D1SM00646K crossref_primary_10_1016_j_bbamem_2024_184349 crossref_primary_10_1063_5_0144544 crossref_primary_10_1142_S0219887817500621 crossref_primary_10_1103_PhysRevE_104_044405 crossref_primary_10_1039_C6SM01686C crossref_primary_10_1063_4_0000041 crossref_primary_10_1038_s42254_019_0128_1 crossref_primary_10_1039_C9CP06059F crossref_primary_10_3390_membranes11090655 crossref_primary_10_1039_C9NR07977G crossref_primary_10_1073_pnas_2008789117 crossref_primary_10_1140_epje_i2018_11607_x crossref_primary_10_1134_S1063776118030111 crossref_primary_10_1016_j_colsurfb_2023_113396 crossref_primary_10_1039_C9SM02111F crossref_primary_10_1140_epje_s10189_023_00400_9 |
| Cites_doi | 10.1063/1.1676380 10.1073/pnas.72.8.3111 10.1038/nature04394 10.1051/jphys:0197500360110103500 10.1103/PhysRevE.52.4251 10.1021/la00011a012 10.1209/0295-5075/95/28008 10.1103/PhysRevLett.96.178302 10.1103/PhysRevLett.82.221 10.1039/C5CC00712G 10.1103/PhysRevE.81.051909 10.1209/epl/i2002-00163-6 10.1529/biophysj.105.075838 10.1016/0301-4622(93)E0077-I 10.1103/PhysRevE.79.031915 10.1063/1.3660673 10.1103/PhysRevLett.102.128101 10.1016/S0006-3495(86)83550-0 10.1140/epje/i2010-10551-1 10.1209/0295-5075/23/6/013 10.1039/a807883a 10.1209/0295-5075/97/68010 10.1016/S0006-3495(00)76304-1 10.1016/0005-2736(73)90143-0 10.1080/00018739700101488 10.1209/0295-5075/23/1/012 10.1038/349475a0 10.1039/c1sm05477e 10.1103/PhysRevLett.93.108103 10.1529/biophysj.107.105395 10.1103/PhysRevLett.102.018102 10.1016/0021-9797(81)90200-9 10.1103/PhysRevLett.109.058102 |
| ContentType | Journal Article |
| Copyright | Copyright © EPLA, 2015 |
| Copyright_xml | – notice: Copyright © EPLA, 2015 |
| DBID | BSCLL AAYXX CITATION 7U5 8FD H8D L7M |
| DOI | 10.1209/0295-5075/111/18004 |
| DatabaseName | Istex CrossRef Solid State and Superconductivity Abstracts Technology Research Database Aerospace Database Advanced Technologies Database with Aerospace |
| DatabaseTitle | CrossRef Aerospace Database Solid State and Superconductivity Abstracts Technology Research Database Advanced Technologies Database with Aerospace |
| DatabaseTitleList | Aerospace Database Aerospace Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Physics |
| DocumentTitleAlternate | Dynamics of an asymmetric bilayer lipid membrane in a viscous solvent |
| EISSN | 1286-4854 |
| EndPage | p1-18004-p6 |
| ExternalDocumentID | 10_1209_0295_5075_111_18004 ark_67375_80W_C3BL1R9R_M epl17203 |
| GroupedDBID | -~X 1JI 4.4 5B3 5GY 5VS 5ZH 6TJ 7.M 7.Q AAFWJ AAGCD AAGID AAJIO AAJKP AALHV AATNI ABCXL ABGRX ABQJV ABVAM ABZDU ACACO ACAFW ACBEA ACGFS ACHIP ACNCT ADACN AEFHF AENEX AFYNE AKPSB ALMA_UNASSIGNED_HOLDINGS AOAED ATQHT AZPVJ CBCFC CEBXE CJUJL CRLBU CS3 DU5 EBS EDWGO EJD EMSAF EPQRW EQZZN F5P HAK H~9 IHE IJHAN IOP IZVLO KOT LAP M45 MV1 N5L N9A NS0 NT- NT. P2P PIG PJBAE R4D RED REP RID RIN RNS ROL RPA SJN SY9 TN5 UCJ UPT ZMT ~02 02O 042 186 1PV 1WK ABTAH AERVB AFFNX AHSEE AI. BBWZM BSCLL FEDTE HVGLF JCGBZ MVM Q02 S3P T37 VH1 XOL ZE2 ZY4 AAYXX CITATION 7U5 8FD H8D L7M |
| ID | FETCH-LOGICAL-c499t-50ebdf9f0d091bb46d3a05841561706c1a4b5789a471af28e6b548d9e141ac133 |
| ISSN | 0295-5075 |
| IngestDate | Fri Aug 16 01:19:14 EDT 2024 Thu Oct 10 21:12:34 EDT 2024 Fri Aug 23 02:32:19 EDT 2024 Wed Oct 30 09:30:24 EDT 2024 Wed Aug 21 03:41:02 EDT 2024 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 1 |
| Language | English |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c499t-50ebdf9f0d091bb46d3a05841561706c1a4b5789a471af28e6b548d9e141ac133 |
| Notes | ark:/67375/80W-C3BL1R9R-M istex:25DDE939398F0CB8192355311A2495A9C9C1873A publisher-ID:epl17203 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| OpenAccessLink | http://eprints.whiterose.ac.uk/88234/1/1507.00023v1.pdf |
| PQID | 3110106156 |
| PQPubID | 1806341 |
| PageCount | 6 |
| ParticipantIDs | iop_journals_10_1209_0295_5075_111_18004 crossref_primary_10_1209_0295_5075_111_18004 proquest_miscellaneous_1753509044 proquest_journals_3110106156 istex_primary_ark_67375_80W_C3BL1R9R_M |
| PublicationCentury | 2000 |
| PublicationDate | 2015-07-01 |
| PublicationDateYYYYMMDD | 2015-07-01 |
| PublicationDate_xml | – month: 07 year: 2015 text: 2015-07-01 day: 01 |
| PublicationDecade | 2010 |
| PublicationPlace | Les Ulis |
| PublicationPlace_xml | – name: Les Ulis |
| PublicationTitle | Europhysics letters |
| PublicationTitleAbbrev | EPL |
| PublicationTitleAlternate | EPL |
| PublicationYear | 2015 |
| Publisher | EDP Sciences, IOP Publishing and Società Italiana di Fisica IOP Publishing |
| Publisher_xml | – name: EDP Sciences, IOP Publishing and Società Italiana di Fisica – name: IOP Publishing |
| References | 22 23 24 Pott T. (25) 2002; 59 27 28 Boal D. (29) 2002 Schmid F. (26) 2011; 95 30 31 10 32 11 33 34 13 35 15 16 Pfeiffer W. (14) 1993; 23 17 Hömberg M. (18) 2012; 97 19 Seifert U. (12) 1993; 23 1 2 3 5 6 7 8 9 Nelson P. (4) 2004 20 21 |
| References_xml | – ident: 8 doi: 10.1063/1.1676380 – ident: 31 doi: 10.1073/pnas.72.8.3111 – ident: 1 doi: 10.1038/nature04394 – ident: 10 doi: 10.1051/jphys:0197500360110103500 – ident: 9 doi: 10.1103/PhysRevE.52.4251 – ident: 11 doi: 10.1021/la00011a012 – volume: 95 issn: 0295-5075 year: 2011 ident: 26 publication-title: EPL doi: 10.1209/0295-5075/95/28008 contributor: fullname: Schmid F. – ident: 20 doi: 10.1103/PhysRevLett.96.178302 – ident: 33 doi: 10.1103/PhysRevLett.82.221 – ident: 35 doi: 10.1039/C5CC00712G – ident: 7 doi: 10.1103/PhysRevE.81.051909 – volume: 59 start-page: 87 issn: 0295-5075 year: 2002 ident: 25 publication-title: Europhys. Lett. doi: 10.1209/epl/i2002-00163-6 contributor: fullname: Pott T. – ident: 27 doi: 10.1529/biophysj.105.075838 – ident: 13 doi: 10.1016/0301-4622(93)E0077-I – year: 2004 ident: 4 publication-title: Biological Physics contributor: fullname: Nelson P. – ident: 28 doi: 10.1103/PhysRevE.79.031915 – ident: 22 doi: 10.1063/1.3660673 – ident: 17 doi: 10.1103/PhysRevLett.102.128101 – ident: 34 doi: 10.1016/S0006-3495(86)83550-0 – year: 2002 ident: 29 publication-title: Mechanics of the Cell contributor: fullname: Boal D. – ident: 15 doi: 10.1140/epje/i2010-10551-1 – volume: 23 start-page: 457 issn: 0295-5075 year: 1993 ident: 14 publication-title: Europhys. Lett. doi: 10.1209/0295-5075/23/6/013 contributor: fullname: Pfeiffer W. – ident: 16 doi: 10.1039/a807883a – volume: 97 issn: 0295-5075 year: 2012 ident: 18 publication-title: EPL doi: 10.1209/0295-5075/97/68010 contributor: fullname: Hömberg M. – ident: 21 doi: 10.1016/S0006-3495(00)76304-1 – ident: 3 doi: 10.1016/0005-2736(73)90143-0 – ident: 30 doi: 10.1080/00018739700101488 – volume: 23 start-page: 71 issn: 0295-5075 year: 1993 ident: 12 publication-title: Europhys. Lett. doi: 10.1209/0295-5075/23/1/012 contributor: fullname: Seifert U. – ident: 2 doi: 10.1038/349475a0 – ident: 24 doi: 10.1039/c1sm05477e – ident: 6 doi: 10.1103/PhysRevLett.93.108103 – ident: 19 doi: 10.1529/biophysj.107.105395 – ident: 5 doi: 10.1103/PhysRevLett.102.018102 – ident: 32 doi: 10.1016/0021-9797(81)90200-9 – ident: 23 doi: 10.1103/PhysRevLett.109.058102 |
| SSID | ssj0011816 |
| Score | 2.3508546 |
| Snippet | Bilayer lipid membranes (BLMs) are an essential component of many biological systems, forming a functional barrier between the cell and the surrounding... |
| SourceID | proquest crossref istex iop |
| SourceType | Aggregation Database Publisher |
| StartPage | 18004 |
| SubjectTerms | 87.15.A 87.16.D 87.16.dj Asymmetry Coupled modes Density Dynamics Joining Lipids Mathematical models Membranes Monolayers Solvents |
| Title | Dynamics of an asymmetric bilayer lipid membrane in a viscous solvent |
| URI | https://iopscience.iop.org/article/10.1209/0295-5075/111/18004 https://api.istex.fr/ark:/67375/80W-C3BL1R9R-M/fulltext.pdf https://www.proquest.com/docview/3110106156 https://search.proquest.com/docview/1753509044 |
| Volume | 111 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3db9MwELfaISReEJ-iMJCREEIyyfJhp8kjrJ3GBFvVDY23yIltFJGk1dJNwF_P2U7SwCQ0HniJKse6Wnfny93vzmeEXjGmEhpx5gjFmANffOlkksVOFqowFDyKldAHhQ9Pp8df4tmczkejn13U34_9V0nDGMhan5z9B2n3RGEAfoPM4QlSh-eN5D6zV8ybCg3Yu7z5UVX61qycZEXJwcEmZbEuBKlkBYGy7RnCyVXR5LoYFtZ21ZXCDPF6I82GlObwzwBZr7-256yXLjlyB4ipRbZdct4PnpRVB60uXDJzh3iDz_ra1BYEmy06s2PN2MliiJht601Not8jHzYGr-FEFOSgaLoCJGvhgoQ54JDatLa0FjiII4fGtrN0b6JbgzzQxWumPzCdU3uSGpEwHwM_9uwFx3_01Zbr0tc56DG6FYCR0uWgp0fHfQYKPB-T5-7otR2r4F_2-rE9XRNm6P_m1YyL1RpiHb1Nv1_7xBu_5eweutsGHPid1ZT7aCTrB-j2wgr0IZp3-oJXCvMab_UFt_qCjb7gTl9wAZNwqy-41ZdH6PPB_Gz_0Gmv1nByCHE3sHqZCZUoT4C_mGU0EiH3wBeFaF73U8p9TjOw5QkH34WrIJZRBqGtSKRPfZ77YfgY7dSrWj5BmMopjyIII4SfUxbnsZRyGimRRZRn_lRN0NuONenadlBJdeQJnEw1J1PNSR2IpoaTE_QG2Je2O6r5-9TXhsc9WX7xTdcpwpzYO0_3w_cf_WWyTD9N0G4nhC3hEBxfjYewaIJe9q_BuOqMGbATmJjqNrbgUXuUPr35sp6hO9t9s4t2NheX8jkaN-LyhVGxX0_DjhM |
| link.rule.ids | 315,782,786,27935,27936 |
| linkProvider | Multiple Vendors |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Dynamics+of+an+asymmetric+bilayer+lipid+membrane+in+a+viscous+solvent&rft.jtitle=Europhysics+letters&rft.au=Bingham%2C+R.+J.&rft.au=Smye%2C+S.+W.&rft.au=Olmsted%2C+P.+D.&rft.date=2015-07-01&rft.pub=EDP+Sciences%2C+IOP+Publishing+and+Societ%C3%A0+Italiana+di+Fisica&rft.issn=0295-5075&rft.eissn=1286-4854&rft.volume=111&rft.issue=1&rft_id=info:doi/10.1209%2F0295-5075%2F111%2F18004&rft.externalDocID=epl17203 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0295-5075&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0295-5075&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0295-5075&client=summon |